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COVID-19 surveillance in wastewater: An epidemiological tool for the monitoring of SARS-CoV-2

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Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fcimb.2022.978643

Keywords

wastewater surveillance; point-of-care diagnostics; COVID-19 pandemic; COVID-19 surveillance system; early warning system

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The COVID-19 pandemic has sparked global interest in understanding the virus's transmission routes, diagnostics, and therapeutics. Studies have shown that viral RNA from SARS-CoV-2 can be detected in human feces present in wastewater, offering the potential for effective monitoring and early detection. However, there are limitations to wastewater surveillance.
The coronavirus disease 2019 (COVID-19) pandemic has prompted a lot of questions globally regarding the range of information about the virus's possible routes of transmission, diagnostics, and therapeutic tools. Worldwide studies have pointed out the importance of monitoring and early surveillance techniques based on the identification of viral RNA in wastewater. These studies indicated the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in human feces, which is shed via excreta including mucus, feces, saliva, and sputum. Subsequently, they get dumped into wastewater, and their presence in wastewater provides a possibility of using it as a tool to help prevent and eradicate the virus. Its monitoring is still done in many regions worldwide and serves as an early warning signal; however, a lot of limitations of wastewater surveillance have also been identified.

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