4.4 Review

The treatment of functional dyspepsia: present and future

Related references

Note: Only part of the references are listed.
Article Gastroenterology & Hepatology

Curcuma longa Linn versus omeprazole in treatment of functional dyspepsia: A randomized, double-blind, placebo-controlled trial

Kachonsak Yongwatana et al.

Summary: The study showed that Curcuma longa Linn can improve dyspeptic symptoms, enhance quality of life, and provide satisfaction comparable to omeprazole in the treatment of functional dyspepsia.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2022)

Article Gastroenterology & Hepatology

Pilot Study of a Self-Administered Hypnosis Intervention for Functional Dyspepsia

Sarah W. Kinsinger et al.

Summary: The fully automated gut-directed hypnosis intervention showed significant improvement in symptoms, quality of life, and emotional well-being in FD patients, demonstrating high feasibility and effectiveness as a potential adjunctive therapy.

DIGESTIVE DISEASES AND SCIENCES (2022)

Article Gastroenterology & Hepatology

A novel duodenal-release formulation of caraway oil and L-menthol is a safe, effective and well tolerated therapy for functional dyspepsia

Brian E. Lacy et al.

Summary: This study investigated the efficacy and safety of a novel formulation of caraway oil and L-menthol (COLM-SST) in patients with functional dyspepsia (FD) through a series of clinical trials and surveys. The results showed that COLM-SST provided rapid relief of FD symptoms and was well-tolerated in long-term use.

BMC GASTROENTEROLOGY (2022)

Article Nutrition & Dietetics

A Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Comparative Clinical Study to Evaluate the Efficacy and Safety of OLNP-06 versus Placebo in Subjects with Functional Dyspepsia

Sanjib Kumar Panda et al.

Summary: OLNP-06, a standardized ginger extract product with higher amount of total gingerols formulated with proprietary Aqueosome technology, was evaluated in a clinical study on patients with functional dyspepsia. The study showed significant improvements in clinical outcomes and demonstrated excellent safety profile.

JOURNAL OF DIETARY SUPPLEMENTS (2022)

Article Gastroenterology & Hepatology

Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study

Ami D. Sperber et al.

Summary: FGIDs have a high prevalence globally, especially among women. Individuals with FGIDs experience lower quality of life and require more frequent medical visits. The proportion of irritable bowel syndrome patients diagnosed using the Rome IV criteria is lower compared to the Rome III criteria.

GASTROENTEROLOGY (2021)

Review Gastroenterology & Hepatology

Diagnostic Evaluation of Gastric Motor and Sensory Disorders

Brian E. Lacy et al.

Summary: Disorders of gastric motor and sensory function affect 10%-20% of the world's population, impacting nutrition and quality of life. Accurate diagnosis relies on understanding epidemiology, risk factors, and careful clinical history focused on symptoms.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2021)

Review Gastroenterology & Hepatology

Small Intestinal Bacterial Overgrowth in Functional Dyspepsia: A Systematic Review and Meta-Analysis

Saravana Ruban Gurusamy et al.

Summary: This systematic review and meta-analysis found a significant association between functional dyspepsia (FD) and small intestinal bacterial overgrowth (SIBO), with SIBO prevalence higher in FD patients compared to controls. The quality of evidence was low due to heterogeneity in breath test types and clinical factors. Further well-designed studies are needed to confirm the link between SIBO and FD.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2021)

Article Gastroenterology & Hepatology

Efficacy and safety of spore-forming probiotics in the treatment of functional dyspepsia: a pilot randomised, double-blind, placebo-controlled trial

Lucas Wauters et al.

Summary: In this study, probiotics were shown to be effective and safe in the treatment of functional dyspepsia, with potentially beneficial impacts on immune and microbial changes.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2021)

Review Gastroenterology & Hepatology

Meta-Analysis: Placebo Response and Its Determinants in Functional Dyspepsia

Xinyi Huang et al.

Summary: Placebo response rates in double-blinded RCTs of functional dyspepsia depend on efficacy criteria. Trials assessing complete symptom relief show stable low placebo response rates in the short term.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2021)

Article Gastroenterology & Hepatology

Novel concepts in the pathophysiology and treatment of functional dyspepsia

Lucas Wauters et al.

Article Gastroenterology & Hepatology

Acupuncture of different treatment frequency in postprandial distress syndrome: A pilot randomized clinical trial

Yu Wang et al.

NEUROGASTROENTEROLOGY AND MOTILITY (2020)

Review Gastroenterology & Hepatology

Diet and functional dyspepsia: Clinical correlates and therapeutic perspectives

Marcella Pesce et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2020)

Review Gastroenterology & Hepatology

Gastroparesis and functional dyspepsia: different diseases or different ends of the spectrum?

David J. Cangemi et al.

CURRENT OPINION IN GASTROENTEROLOGY (2020)

Article Gastroenterology & Hepatology

Epigastric pain syndrome: What can traditional Chinese medicine do? A randomized controlled trial of Biling Weitong Granules

Yan-Dong Wen et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2020)

Review Medicine, General & Internal

Functional Gastrointestinal Disorders 3 Functional dyspepsia

Alexander C. Ford et al.

LANCET (2020)

Article Gastroenterology & Hepatology

The efficacy of oral Zhizhu Kuanzhong, a traditional Chinese medicine, in patients with postprandial distress syndrome

Yinglian Xiao et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2019)

Letter Gastroenterology & Hepatology

Iberogast-Induced Acute Liver Failure-Reexposure and In Vitro Assay Support Causality

Florian Gerhardt et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2019)

Review Gastroenterology & Hepatology

Prokinetics for Functional Dyspepsia: A Systematic Review and Meta-Analysis of Randomized Control Trials

Rapat Pittayanon et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2019)

Review Gastroenterology & Hepatology

Complementary and alternative treatment in functional dyspepsia

Giuseppe Chiarioni et al.

UNITED EUROPEAN GASTROENTEROLOGY JOURNAL (2018)

Review Clinical Neurology

Virtual Reality as a Clinical Tool for Pain Management

Ali Pourmand et al.

CURRENT PAIN AND HEADACHE REPORTS (2018)

Article Gastroenterology & Hepatology

Efficacy and safety of nortriptyline in functional dyspepsia in Asians: A randomized double-blind placebo-controlled trial

Uayporn Kaosombatwattana et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2018)

Article Gastroenterology & Hepatology

Effects of Antidepressants on Gastric Function in Patients with Functional Dyspepsia

B. E. Lacy et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2018)

Article Gastroenterology & Hepatology

Low-dose imipramine for refractory functional dyspepsia: a randomised, double-blind, placebo-controlled trial

Pui Kuan Cheong et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2018)

Review Gastroenterology & Hepatology

Efficacy of psychotropic drugs in functional dyspepsia: systematic review and meta-analysis

Alexander C. Ford et al.

Article Gastroenterology & Hepatology

Pathophysiological Abnormalities in Functional Dyspepsia Subgroups According to the Rome III Criteria

H. Vanheel et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2017)

Review Gastroenterology & Hepatology

Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis

James K. Y. Hooi et al.

GASTROENTEROLOGY (2017)

Article Gastroenterology & Hepatology

Prevalence of Gastric Motility Disorders in Patients with Functional Dyspepsia

Haruki Asano et al.

JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY (2017)

Review Gastroenterology & Hepatology

ACG and CAG Clinical Guideline: Management of Dyspepsia

Paul M. Moayyedi et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2017)

Article Gastroenterology & Hepatology

Functional dyspepsia is associated with duodenal eosinophilia in an Australian paediatric cohort

L. Wauters et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2017)

Article Gastroenterology & Hepatology

Randomised clinical trial: rifaximin versus placebo for the treatment of functional dyspepsia

V. P. Y. Tan et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2017)

Article Gastroenterology & Hepatology

Efficacy of Mirtazapine in Patients With Functional Dyspepsia and Weight Loss

Jan Tack et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2016)

Article Gastroenterology & Hepatology

Gastroduodenal Disorders

Vincenzo Stanghellini et al.

GASTROENTEROLOGY (2016)

Article Gastroenterology & Hepatology

Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: A Multicenter, Randomized Controlled Study

Nicholas J. Talley et al.

GASTROENTEROLOGY (2015)

Article Gastroenterology & Hepatology

Medication Risk-Taking Behavior in Functional Dyspepsia Patients

Brian E. Lacy et al.

CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2015)

Article Gastroenterology & Hepatology

Duodenal eosinophilia and early satiety in functional dyspepsia: Confirmation of a positive association in an Australian cohort

Marjorie M. Walker et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2014)

Article Gastroenterology & Hepatology

Xiaoyao pill for treatment of functional dyspepsia in perimenopausal women with depression

Han-Guang Du et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Article Gastroenterology & Hepatology

Functional dyspepsia: the economic impact to patients

B. E. Lacy et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2013)

Article Gastroenterology & Hepatology

Overlap of functional dyspepsia and GERD-diagnostic and treatment implications

Eamonn M. M. Quigley et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2013)

Article Gastroenterology & Hepatology

A survey of pharmacological and nonpharmacological treatment of functional gastrointestinal disorders

Edith Lahner et al.

UNITED EUROPEAN GASTROENTEROLOGY JOURNAL (2013)

Article Gastroenterology & Hepatology

Efficacy of Buspirone, a Fundus-Relaxing Drug, in Patients With Functional Dyspepsia

Jan Tack et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2012)

Article Gastroenterology & Hepatology

Functional dyspepsia impairs quality of life in the adult population

P. Aro et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2011)

Article Medicine, General & Internal

Helicobacter pylori Eradication in Functional Dyspepsia HEROES Trial

Luiz Edmundo Mazzoleni et al.

ARCHIVES OF INTERNAL MEDICINE (2011)

Article Gastroenterology & Hepatology

Factors influencing dyspepsia-related consultation: differences between a rural and an urban population

S. Mahadeva et al.

NEUROGASTROENTEROLOGY AND MOTILITY (2011)

Article Gastroenterology & Hepatology

Effect of ginger on gastric motility and symptoms of functional dyspepsia

Ming-Luen Hu et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2011)

Article Gastroenterology & Hepatology

Epidemiology of Functional Dyspepsia and Subgroups in the Italian General Population: An Endoscopic Study

Rocco Maurizio Zagari et al.

GASTROENTEROLOGY (2010)

Review Psychology, Clinical

The effectiveness of virtual reality distraction for pain reduction: A systematic review

Kevin M. Malloy et al.

CLINICAL PSYCHOLOGY REVIEW (2010)

Article Gastroenterology & Hepatology

Non-ulcer dyspepsia and duodenal eosinophilia:: An adult endoscopic population-based case-control study

Nicholas J. Talley et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2007)

Article Gastroenterology & Hepatology

Who consults with dyspepsia? Results from a longitudinal 10-yr follow-up study

Alexander C. Ford et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2007)

Article Gastroenterology & Hepatology

Prokinetic effect of gut-oriented hypnosis on gastric emptying

G Chiarioni et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2006)

Article Gastroenterology & Hepatology

Long-term improvement in functional dyspepsia using hypnotherapy

EL Calvert et al.

GASTROENTEROLOGY (2002)