Association of body composition fat parameters and breast density in mammography by menopausal status

Article Multidisciplinary Sciences

Association between body fat parameters and arterial stiffness

Hack-Lyoung Kim et al.

Summary: This study found that baPWV was associated with WHR and VFA, but not with BMI and WC. This suggests that arterial stiffness may have a stronger connection to abdominal obesity than overall obesity.

SCIENTIFIC REPORTS (2021)

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Article Medicine, General & Internal

Association of the Interaction Between Mammographic Breast Density, Body Mass Index, and Menopausal Status With Breast Cancer Risk Among Korean Women

Thi Xuan Mai Tran et al.

Summary: This study investigates the interactive association of mammographic breast density and BMI with breast cancer risks among premenopausal and postmenopausal women, highlighting a synergistic effect on breast cancer risk for women with high breast density and high BMI, particularly among postmenopausal women. Incorporating both factors into risk stratification for population-based screening may be beneficial in detecting breast cancer early in women with overweight or obesity and dense breast tissue.

JAMA NETWORK OPEN (2021)

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Review Oncology

Obese Adipose Tissue as a Driver of Breast Cancer Growth and Development: Update and Emerging Evidence

Priya Bhardwaj et al.

Summary: This review examines the interaction between obesity and breast cancer, focusing on estrogen, inflammatory mediators, and adipokines derived from breast adipose tissue, and how they are linked to oxidative stress, DNA damage, and pro-oncogenic transcriptional programs. Strategies targeting these factors for decreasing the risk of obesity-induced breast epithelial cell transformation and breast cancer development are evaluated for feasibility and efficacy.

FRONTIERS IN ONCOLOGY (2021)

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Article Multidisciplinary Sciences

Association between skeletal muscle mass and mammographic breast density

Kwan Ho Lee et al.

Summary: The study found a relationship between skeletal muscle mass index (SMI) and mammographic density (MD), suggesting SMI as an independent predictor for dense breast. SMI may influence breast tissue through similar growth mechanisms, further research is needed to confirm its causal link with breast cancer risk.

SCIENTIFIC REPORTS (2021)

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Article Medicine, General & Internal

Association of Breast Density With Breast Cancer Risk Among Women Aged 65 Years or Older by Age Group and Body Mass Index

Shailesh M. Advani et al.

Summary: The study found that breast density is associated with an increased risk of invasive breast cancer among women aged 65 years or older, and body mass index (BMI) does not modify this association. Therefore, when discussing screening mammography in this age group, both breast density and life expectancy should be taken into consideration.

JAMA NETWORK OPEN (2021)

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Article Medicine, General & Internal