4.7 Review

Plant-Based Diets and Lipid, Lipoprotein, and Inflammatory Biomarkers of Cardiovascular Disease: A Review of Observational and Interventional Studies

Related references

Note: Only part of the references are listed.
Review Cardiac & Cardiovascular Systems

High-density lipoprotein revisited: biological functions and clinical relevance

Arnold von Eckardstein et al.

Summary: Previous interest in HDL focused on its role in atherosclerotic cardiovascular disease, but recent studies show that HDL has broader physiological functions and is associated with various diseases.

EUROPEAN HEART JOURNAL (2023)

Article Cardiac & Cardiovascular Systems

2021 ESC Guidelines on cardiovascular disease prevention in clinical practice

Frank L. J. Visseren et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2022)

Article Cardiac & Cardiovascular Systems

Association of Apolipoprotein B-Containing Lipoproteins and Risk of Myocardial Infarction in Individuals With and Without Atherosclerosis Distinguishing Between Particle Concentration, Type, and Content

Nicholas A. Marston et al.

Summary: This study found that the number of apoB-containing lipoproteins plays a crucial role in predicting cardiovascular risk independently of cholesterol or TG content. Lowering the concentration of all apoB-containing lipoproteins should be the primary focus of therapeutic strategies.

JAMA CARDIOLOGY (2022)

Article Nutrition & Dietetics

Pro-vegetarian food patterns and cardiometabolic risk in the PREDIMED-Plus study: a cross-sectional baseline analysis

Alejandro Oncina-Canovas et al.

Summary: The study found that higher adherence to general and healthful PVG food patterns was associated with lower cardiovascular risk, while higher adherence to unhealthful PVG was associated with higher cardiovascular risk.

EUROPEAN JOURNAL OF NUTRITION (2022)

Article Nutrition & Dietetics

A healthy plant-based diet is favorably associated with cardiometabolic risk factors among participants of South Asian ancestry

Shilpa N. Bhupathiraju et al.

Summary: This study evaluated the association between plant-based diet quality and cardiometabolic risks among participants of South Asian ancestry living in the United States. The results showed that a higher intake of healthful plant-based foods was associated with a lower cardiometabolic risk profile.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)

Article Cardiac & Cardiovascular Systems

Practical, Evidence-Based Approaches to Nutritional Modifications to Reduce Atherosclerotic Cardiovascular Disease: An American Society For Preventive Cardiology Clinical Practice Statement

Danielle Belardo et al.

Summary: Despite advancements in cardiovascular care, cardiovascular disease remains the leading cause of death in the US. Evidence shows that dietary interventions can effectively prevent cardiovascular disease. This statement emphasizes the importance of evidence-based dietary patterns in preventing atherosclerotic cardiovascular disease and its risk factors. A diet rich in fruits, vegetables, legumes, nuts, seeds, plant protein, and fatty fish is optimal for preventing atherosclerotic cardiovascular disease.

AMERICAN JOURNAL OF PREVENTIVE CARDIOLOGY (2022)

Article Green & Sustainable Science & Technology

The carbon opportunity cost of animal-sourced food production on land

Matthew N. Hayek et al.

Summary: The shift in global food production towards plant-based diets by 2050 could sequester 332-547 GtCO(2), equivalent to 99-163% of the CO(2) emissions budget consistent with a 66% chance of limiting warming to 1.5 degrees C. This represents a significant opportunity for carbon sequestration through ecosystem restoration, highlighting the potential benefits of dietary changes for mitigating climate change.

NATURE SUSTAINABILITY (2021)

Review Cardiac & Cardiovascular Systems

2021 Dietary Guidance to Improve Cardiovascular Health: A Scientific Statement From the American Heart Association

Alice H. Lichtenstein et al.

Summary: Poor diet quality is closely linked to the increased risk of cardiovascular disease, and this scientific statement underscores the importance of healthy dietary patterns. Evidence-based dietary guidance includes principles such as energy balance, consuming a variety of fruits and vegetables, and choosing healthy sources of protein. Challenges to adhering to heart-healthy dietary patterns include targeted marketing of unhealthy foods and structural racism.

CIRCULATION (2021)

Article Biochemistry & Molecular Biology

Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake

Kevin D. Hall et al.

Summary: In an inpatient, randomized controlled crossover trial, participants consumed 550-700 fewer calories per day when following a plant-based, low-fat diet with a high glycemic load compared with an animal-based, low-carbohydrate diet with a low glycemic load; weight loss was comparable between the two diets and there were no significant differences in hunger or enjoyment of the meals.

NATURE MEDICINE (2021)

Article Nutrition & Dietetics

Association between Different Types of Plant-Based Diets and Risk of Dyslipidemia: A Prospective Cohort Study

Kyueun Lee et al.

Summary: The study found that different types of plant-based diets are associated with dyslipidemia in Asian populations, and different dietary patterns can affect the development of individual lipid disorders. High-quality plant-based foods are important for preventing dyslipidemia in populations with high plant food consumption.

NUTRIENTS (2021)

Article Nutrition & Dietetics

Adherence to a Plant-Based Diet and Consumption of Specific Plant Foods-Associations with 3-Year Weight-Loss Maintenance and Cardiometabolic Risk Factors: A Secondary Analysis of the PREVIEW Intervention Study

Ruixin Zhu et al.

Summary: Long-term consumption of nuts, fruits, and vegetables may be beneficial for weight management and cardiometabolic health, whereas an overall plant-based diet may improve weight management only.

NUTRIENTS (2021)

Review Nutrition & Dietetics

Association between Plant-Based Dietary Patterns and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies

Zuo Hua Gan et al.

Summary: Plant-based diets with higher adherence are associated with lower risks of cardiovascular disease and coronary heart disease. However, the association with stroke risk remains inconclusive. Higher plant-based diet index and healthful PDI scores are related to reduced cardiovascular disease risk.

NUTRIENTS (2021)

Review Biochemistry & Molecular Biology

Confounders in Identification and Analysis of Inflammatory Biomarkers in Cardiovascular Diseases

Qurrat Ul Ain et al.

Summary: Proinflammatory biomarkers are increasingly used in epidemiological and intervention studies to evaluate the association of systemic inflammation with cardiovascular diseases. While elevated levels of these biomarkers are strongly correlated with various cardiovascular diseases, the underlying mechanisms are still unclear. Factors such as age, sex, socioeconomic status, BMI, medication usage, methodological inconsistencies, and other confounding factors may contribute to variations in study results.

BIOMOLECULES (2021)

Review Biochemistry & Molecular Biology

Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target

Jennifer Behbodikhah et al.

Summary: Apolipoprotein B plays a crucial role in atherogenic lipoproteins, with two major isoforms: apoB48 and apoB100. ApoB concentration serves as a direct measure of circulating atherogenic lipoproteins, independent of particle cholesterol content, making it a more accurate indicator of cardiovascular risk than total cholesterol or LDL cholesterol.

METABOLITES (2021)

Article Medicine, General & Internal

Association of plant-based diet index with inflammatory markers and sleep quality in overweight and obese female adults: A cross-sectional study

Sanaz Pourreza et al.

Summary: Adherence to a healthful plant-based diet is associated with lower levels of hs-CRP, while adherence to an unhealthful plant-based diet is associated with higher concentrations of hs-CRP. Adherence to an unhealthful plant-based diet is associated with lower sleep quality.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2021)

Article Geriatrics & Gerontology

Association Between Dietary Patterns in Midlife and Healthy Ageing in Chinese Adults: The Singapore Chinese Health Study

Yan-Feng Zhou et al.

Summary: This study found that adherence to various healthy dietary patterns in midlife is associated with a higher likelihood of healthy ageing in later life among Chinese older adults.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2021)

Article Food Science & Technology

Effects of a dietary intervention with Mediterranean and vegetarian diets on hormones that influence energy balance: results from the CARDIVEG study

Monica Dinu et al.

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2020)

Article Nutrition & Dietetics

Genetic susceptibility, plant-based dietary patterns, and risk of cardiovascular disease

Yoriko Heianza et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2020)

Article Biochemistry & Molecular Biology

Dyslipidemia and cardiovascular disease risk among the MASHAD study population

Mahshad Hedayatnia et al.

LIPIDS IN HEALTH AND DISEASE (2020)

Article Medicine, General & Internal

Association Between Healthy Eating Patterns and Risk of Cardiovascular Disease

Zhilei Shan et al.

JAMA INTERNAL MEDICINE (2020)

Article Urology & Nephrology

Plant-based diets, insulin sensitivity and inflammation in elderly men with chronic kidney disease

Ailema Gonzalez-Ortiz et al.

JOURNAL OF NEPHROLOGY (2020)

Article Cardiac & Cardiovascular Systems

VLDL Cholesterol Accounts for One-Half of the Risk of Myocardial Infarction Associated With apoB-Containing Lipoproteins

Mie Balling et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

Review Cardiac & Cardiovascular Systems

Inflammation and cardiovascular disease: From mechanisms to therapeutics

Abdulhamied Alfaddagh et al.

AMERICAN JOURNAL OF PREVENTIVE CARDIOLOGY (2020)

Article Medicine, General & Internal

Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease

Brian A. Ference et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2019)

Article Cardiac & Cardiovascular Systems

Changes in Plant-Based Diet Quality and Total and Cause-Specific Mortality

Megu Y. Baden et al.

CIRCULATION (2019)

Review Green & Sustainable Science & Technology

Which Diet Has the Least Environmental Impact on Our Planet? A Systematic Review of Vegan, Vegetarian and Omnivorous Diets

Bingli Clark Chai et al.

SUSTAINABILITY (2019)

Article Medicine, General & Internal

Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction

Jean-Claude Tardif et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Review Cardiac & Cardiovascular Systems

Apolipoprotein B Particles and Cardiovascular Disease A Narrative Review

Allan D. Sniderman et al.

JAMA CARDIOLOGY (2019)

Article Medicine, General & Internal

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts

R. Estruch et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Review Cardiac & Cardiovascular Systems

Portfolio Dietary Pattern and Cardiovascular Disease: A Systematic Review and Meta-analysis of Controlled Trials

Laura Chiavaroli et al.

PROGRESS IN CARDIOVASCULAR DISEASES (2018)

Article Multidisciplinary Sciences

Reducing food's environmental impacts through producers and consumers

J. Poore et al.

SCIENCE (2018)

Article Nutrition & Dietetics

The Role of Tree Nuts and Peanuts in the Prevention of Coronary Heart Disease: Multiple Potential Mechanisms

Penny M. Kris-Etherton et al.

JOURNAL OF NUTRITION (2018)

Article Cardiac & Cardiovascular Systems

Anti-Inflammatory Effects of a Vegan Diet Versus the American Heart Association-Recommended Diet in Coronary Artery Disease Trial

Binita Shah et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)

Review Public, Environmental & Occupational Health

Legume consumption and CVD risk: a systematic review and meta-analysis

Stefano Marventano et al.

PUBLIC HEALTH NUTRITION (2017)

Article Public, Environmental & Occupational Health

Fresh fruit consumption and all-cause and cause-specific mortality: findings from the China Kadoorie Biobank

Huaidong Du et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2017)

Article Pharmacology & Pharmacy

The effect of dietary protein source on serum lipids: Secondary data analysis from a randomized clinical trial

Anda R. Gonciulea et al.

JOURNAL OF CLINICAL LIPIDOLOGY (2017)

Article Cardiac & Cardiovascular Systems

Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease in US Adults

Ambika Satija et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2017)

Article Medicine, General & Internal

Evacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease

A. Michael Lincoff et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

P. M. Ridker et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Public, Environmental & Occupational Health

Lifestyles and Mortality in Taiwan: An 11-Year Follow-up Study

Yen-Huai Lin et al.

ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH (2017)

Article Cardiac & Cardiovascular Systems

Discordance Between Apolipoprotein B and LDL-Cholesterol in Young Adults Predicts Coronary Artery Calcification The CARDIA Study

John T. Wilkins et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

Article Medicine, General & Internal

Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality

Mingyang Song et al.

JAMA INTERNAL MEDICINE (2016)

Article Medicine, General & Internal

Association of Specific Dietary Fats With Total and Cause-Specific Mortality

Dong D. Wang et al.

JAMA INTERNAL MEDICINE (2016)

Review Nutrition & Dietetics

Whole-grain and blood lipid changes in apparently healthy adults: a systematic review and meta-analysis of randomized controlled studies

Pernille L. B. Holloender et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2015)

Article Food Science & Technology

Effect of dietary fiber on circulating C-reactive protein in overweight and obese adults: a meta-analysis of randomized controlled trials

Jun Jiao et al.

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2015)

Review Medicine, General & Internal

Inflammation and plaque vulnerability

G. K. Hansson et al.

JOURNAL OF INTERNAL MEDICINE (2015)

Article Cardiac & Cardiovascular Systems

Fasting Triglycerides Predict Recurrent Ischemic Events in Patients With Acute Coronary Syndrome Treated With Statins

Gregory G. Schwartz et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2015)

Article Cardiac & Cardiovascular Systems

Apolipoprotein B improves risk assessment of future coronary heart disease in the Framingham Heart Study beyond LDL-C and non-HDL-C

Michael J. Pencina et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2015)

Article Cardiac & Cardiovascular Systems

TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: Crosstalk between NF-κB and PPAR-γ

Youzhi Zhang et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)

Article Medicine, General & Internal

HDL Cholesterol Efflux Capacity and Incident Cardiovascular Events

Anand Rohatgi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Review Public, Environmental & Occupational Health

Whole grain and refined grain consumption and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis of cohort studies

Dagfinn Aune et al.

EUROPEAN JOURNAL OF EPIDEMIOLOGY (2013)

Article Pharmacology & Pharmacy

High-density lipoproteins: A consensus statement from the National Lipid Association

Peter P. Toth et al.

JOURNAL OF CLINICAL LIPIDOLOGY (2013)

Article Nutrition & Dietetics

Weight Loss Is More Important Than the Diet Type in Improving Adiponectin Levels Among Overweight/Obese Adults

Sushama D. Acharya et al.

JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION (2013)

Article Medicine, General & Internal

Vegetarian Dietary Patterns and Mortality in Adventist Health Study 2

Michael J. Orlich et al.

JAMA INTERNAL MEDICINE (2013)

Review Pharmacology & Pharmacy

Cardiovascular disease risk reduction by raising HDL cholesterol - current therapies and future opportunities

K. Mahdy Ali et al.

BRITISH JOURNAL OF PHARMACOLOGY (2012)

Article Peripheral Vascular Disease

Residual Cardiovascular Risk Despite Optimal LDL Cholesterol Reduction with Statins: The Evidence, Etiology, and Therapeutic Challenges

Uchechukwu K. Sampson et al.

CURRENT ATHEROSCLEROSIS REPORTS (2012)

Review Medicine, Research & Experimental

Opportunities for Using Lipoprotein Subclass Profile by Nuclear Magnetic Resonance Spectroscopy in Assessing Insulin Resistance and Diabetes Prediction

Alexis C. Frazier-Wood et al.

METABOLIC SYNDROME AND RELATED DISORDERS (2012)

Article Medicine, General & Internal

Effects of Dalcetrapib in Patients with a Recent Acute Coronary Syndrome

Gregory G. Schwartz et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Medicine, General & Internal

Nut Consumption and Blood Lipid Levels A Pooled Analysis of 25 Intervention Trials

Joan Sabate et al.

ARCHIVES OF INTERNAL MEDICINE (2010)

Article Public, Environmental & Occupational Health

A Multicomponent Intervention Reduces Body Weight and Cardiovascular Risk at a GEICO Corporate Site

Hope R. Ferdowsian et al.

AMERICAN JOURNAL OF HEALTH PROMOTION (2010)

Review Medicine, General & Internal

Systematic Review: Association of Low-Density Lipoprotein Subfractions With Cardiovascular Outcomes

Stanley Ip et al.

ANNALS OF INTERNAL MEDICINE (2009)

Article Hematology

Ion Mobility Analysis of Lipoprotein Subfractions Identifies Three Independent Axes of Cardiovascular Risk

Kiran Musunuru et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)

Review Cardiac & Cardiovascular Systems

Inflammatory biomarkers in coronary artery disease

Epaminondas Zakynthinos et al.

JOURNAL OF CARDIOLOGY (2009)

Article Cardiac & Cardiovascular Systems

Atherogenic lipoprotein phenotype and LDL size and subclasses in patients with peripheral arterial disease

Manfredi Rizzo et al.

ATHEROSCLEROSIS (2008)

Article Cardiac & Cardiovascular Systems

Impact of triglyceride levels beyond low-density lipoprotein cholesterol after acute coronary syndrome in the PROVE IT-TIMI 22 trial

Michael Miller et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)

Review Hematology

Vascular adhesion molecules in atherosclerosis

Elena Galkina et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)

Article Medicine, General & Internal

The effect of a plant-based diet on plasma lipids in hypercholesterolemic adults - A randomized trial

CD Gardner et al.

ANNALS OF INTERNAL MEDICINE (2005)

Article Medicine, General & Internal

C-reactive protein levels and outcomes after statin therapy

PM Ridker et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Cardiac & Cardiovascular Systems

Atherogenic lipoprotein particles in atherosclerosis

R Carmena et al.

CIRCULATION (2004)

Article Medicine, General & Internal

Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids and C-reactive protein

DJA Jenkins et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)

Article Endocrinology & Metabolism

Impact of margarine enriched with plant sterols on blood lipids, platelet function, and fibrinogen level in young men

M Kozlowska-Wojciechowska et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2003)

Review Multidisciplinary Sciences

Atherosclerosis

AJ Lusis

NATURE (2000)

Article Cardiac & Cardiovascular Systems

Effectiveness of a low-fat vegetarian diet in altering serum lipids in healthy premenopausal women

ND Barnard et al.

AMERICAN JOURNAL OF CARDIOLOGY (2000)

Article Hematology

Lessons from sudden coronary death - A comprehensive morphological classification scheme for atherosclerotic lesions

R Virmani et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2000)