Journal
NUTRIENTS
Volume 14, Issue 21, Pages -Publisher
MDPI
DOI: 10.3390/nu14214681
Keywords
tea; hyperglycemia; insulin resistance; oxidative stress; mitochondrial damage; gut
Categories
Funding
- Guangdong Province Special Fund for Modern Agriculture Industry Technology Innovation Teams [2022KJ120]
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This paper summarizes the important role of catechins in alleviating diabetes and its underlying mechanisms, providing scientific direction for future research on catechin alleviating diabetes.
Catechins are key functional components in tea and have many health benefits, including relieving diabetes. Glucose is necessary for maintaining life. However, when the glucose in the serum exceeds the threshold, it will lead to hyperglycemia. Hyperglycemia is mainly caused by insufficient insulin secretion or insulin resistance. Persistent hyperglycemia can cause various disorders, including retinopathy, nephropathy, neurodegenerative diseases, cardiovascular disease, and diabetes. In this paper, we summarize the research on the underlying mechanisms of catechins in regulating diabetes and elaborate on the mechanisms of catechins in alleviating hyperglycemia by improving insulin resistance, alleviating oxidative stress, regulating mitochondrial function, alleviating endoplasmic reticulum stress, producing anti-inflammatory effects, reducing blood sugar source, and regulating intestinal function. This review will provide scientific direction for future research on catechin alleviating diabetes.
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