4.6 Article

Decoherence of photon entanglement by transmission through brain tissue with Alzheimer?s disease

Journal

BIOMEDICAL OPTICS EXPRESS
Volume 13, Issue 12, Pages 6621-6630

Publisher

Optica Publishing Group
DOI: 10.1364/BOE.474469

Keywords

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Funding

  1. National Science Foundation
  2. Colgate University Picker Interdisciplinary Science Institute
  3. Army Research Office
  4. [PHY-1506321]
  5. [PHY-2011937]
  6. [W911NF-19-1-0373]

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This study investigates the use of quantum entangled photons as a diagnostic tool for distinguishing brain tissue with Alzheimer's disease from healthy tissue. The researchers found that entangled photons lose their entanglement in a different way when passing through brain tissue affected by Alzheimer's disease compared to healthy tissue. The results suggest that quantum measures of entangled photons could be used to identify brain samples with the neurodegenerative disease.
The generation, manipulation and quantification of non-classical light, such as quantum-entangled photon pairs, differs significantly from methods with classical light. Thus, quantum measures could be harnessed to give new information about the interaction of light with matter. In this study we investigate if quantum entanglement can be used to diagnose disease. In particular, we test whether brain tissue from subjects suffering from Alzheimer's disease can be distinguished from healthy tissue. We find that this is indeed the case. Polarization-entangled photons traveling through brain tissue lose their entanglement via a decohering scattering interaction that gradually renders the light in a maximally mixed state. We found that in thin tissue samples (between 120 and 600 micrometers) photons decohere to a distinguishable lesser degree in samples with Alzheimer's disease than in healthy-control ones. Thus, it seems feasible that quantum measures of entangled photons could be used as a means to identify brain samples with the neurodegenerative disease.

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