Journal
BIOMEDICAL OPTICS EXPRESS
Volume 13, Issue 12, Pages 6497-6507Publisher
Optica Publishing Group
DOI: 10.1364/BOE.470665
Keywords
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Funding
- National Research Foundation of Korea
- [NRF-2018K1A4A3A02060572]
- [NRF-2019R1I1A3A01062141]
- [NRF-2020H1D3A1A04080958]
- [NRF-2022R1I1A3073688]
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We report the development of a handheld, smartphone-based spatial frequency domain imaging device. Through experiments with liquid phantoms and human subjects, the device can calculate optical properties and hemoglobin-based chromophores, laying the foundation for a mass-market device for dermatological and cosmetic applications.
We report a handheld, smartphone-based spatial frequency domain imaging device. We first examined the linear dynamic range of the smartphone camera sensor. We then calculated optical properties for a series of liquid phantoms with varying concentrations of nigrosin ink and Intralipid, demonstrating separation of absorption and scattering. The device was then tested on a human wrist, where optical properties and hemoglobin-based chromophores were calculated. Finally, we performed an arterial occlusion on a human hand and captured hemodynamics using our device. We hope to lay the foundation for an accessible SFDI device with mass-market appeal designed for dermatological and cosmetic applications. (c) 2022 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement
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