4.8 Article

Structural basis of transcription recognition of a hydrophobic unnatural base pair by T7 RNA polymerase

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines

Kellie D. Nance et al.

Summary: The COVID-19 mRNA vaccines have utilized the modified nucleobase N1-methylpseudouridine (m1 Psi) to enhance effectiveness, contributing to one of the most efficient vaccine development campaigns. By explaining the development and function of m1 Psi in synthetic mRNAs, this article aims to promote understanding and highlight potential opportunities for chemical innovation in the future.

ACS CENTRAL SCIENCE (2021)

Article Biochemistry & Molecular Biology

Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II

Juntaek Oh et al.

Summary: The study found that eukaryotic RNA polymerase II is capable of selectively recognizing unnatural base pairs with high fidelity, especially when the template strand contains dTPT3. Additionally, a novel 3'-RNA binding site termed the swing state was identified after rNaM addition. These results may pave the way for future studies in the design of transcription and translation strategies in higher organisms with expanded genetic codes.

NATURE CHEMICAL BIOLOGY (2021)

Review Chemistry, Multidisciplinary

Genetic alphabet expansion technology by creating unnatural base pairs

Michiko Kimoto et al.

CHEMICAL SOCIETY REVIEWS (2020)

Article Biochemical Research Methods

Structural and biochemical analysis of DNA lesion-induced RNA polymerase II arrest

Juntaek Oh et al.

METHODS (2019)

Article Multidisciplinary Sciences

Hachimoji DNA and RNA: A genetic system with eight building blocks

Shuichi Hoshika et al.

SCIENCE (2019)

Article Chemistry, Multidisciplinary

Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism

Aaron W. Feldman et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Chemistry, Multidisciplinary

Visual Detection of Amplified DNA by Polymerase Chain Reaction Using a Genetic Alphabet Expansion System

Rie Yamashige et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Chemistry, Multidisciplinary

Structural Basis for Expansion of the Genetic Alphabet with an Artificial Nucleobase Pair

Karin Betz et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Review Chemistry, Multidisciplinary

The Expanded Genetic Alphabet

Denis A. Malyshev et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Chemistry, Multidisciplinary

Dissecting Chemical Interactions Governing RNA Polymerase II Transcriptional Fidelity

Matthew W. Kellinger et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

Article Biochemistry & Molecular Biology

Site-Specific Incorporation of Functional Components into RNA by an Unnatural Base Pair Transcription System

Nobuyuki Morohashi et al.

MOLECULES (2012)

Article Biochemistry & Molecular Biology

PCR Amplification and Transcription for Site-Specific Labeling of Large RNA Molecules by a Two-Unnatural-Base-Pair System

Michiko Kimoto et al.

JOURNAL OF NUCLEIC ACIDS (2012)

Article Biochemical Research Methods

XDS

Wolfgang Kabsch

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Biochemical Research Methods

Features and development of Coot

P. Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Biochemical Research Methods

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Article Chemistry, Multidisciplinary

A Unique Fluorescent Base Analogue for the Expansion of the Genetic Alphabet

Michiko Kimoto et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Article Biochemistry & Molecular Biology

Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation

Bart R. Anderson et al.

NUCLEIC ACIDS RESEARCH (2010)

Article Biochemistry & Molecular Biology

The structural changes of T7 RNA polymerase from transcription initiation to elongation

Thomas A. Steitz

CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)

Article Chemistry, Multidisciplinary

Transcription of an Expanded Genetic Alphabet

Young Jun Seo et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Article Biochemistry & Molecular Biology

An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules

Michiko Kimoto et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Chemistry, Multidisciplinary

An efficient unnatural base pair for PCR amplification

Ichiro Hirao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Article Biochemistry & Molecular Biology

Fluorescent probing for RNA molecules by an unnatural base-pair system

Michiko Kimoto et al.

NUCLEIC ACIDS RESEARCH (2007)

Article Multidisciplinary Sciences

Structural basis for substrate loading in bacterial RNA polymerase

Dmitry G. Vassylyev et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Transient state kinetics of transcription elongation by T7 RNA polymerase

Vasanti Subramanian Anand et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Structural basis for substrate selection by T7 RNA polymerase

D Temiakov et al.

Article Biochemical Research Methods

Crystallization and preliminary crystallographic analysis of T7 RNA polymerase elongation complex

D Temiakov et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2003)

Article Multidisciplinary Sciences

Structure of a T7 RNA polymerase elongation complex at 2.9Å resolution

TH Tahirov et al.

NATURE (2002)

Article Biotechnology & Applied Microbiology

An unnatural base pair for incorporating amino acid analogs into proteins

I Hirao et al.

NATURE BIOTECHNOLOGY (2002)

Article Multidisciplinary Sciences

Unnatural base pairs for specific transcription

T Ohtsuki et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

Roles of histidine 784 and tyrosine 639 in ribose discrimination by T7 RNA polymerase

LG Brieba et al.

BIOCHEMISTRY (2000)