4.7 Article

Probiotics alleviate maternal metabolic disorders and offspring-islet abnormalities in gestational diabetic mice

Related references

Note: Only part of the references are listed.
Article Microbiology

Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis

Y. Grace Cao et al.

Summary: The intestinal epithelium plays a crucial role in sensing and integrating dietary and microbial signals. This study reveals that specific members of the microbiota can modulate the homeostasis of the duodenal epithelium by altering epithelial turnover rate, crypt proliferation, and MHCII expression. Faecalibaculum rodentium is identified as a key species involved in this regulation. This research uncovers a retinoic acid-eosinophil-interferon-gamma-dependent circuit by which the microbiota can influence duodenal epithelial homeostasis.

CELL HOST & MICROBE (2022)

Review Obstetrics & Gynecology

Metformin versus insulin for gestational diabetes: a systematic review and meta-analysis

Le-xin Bao et al.

Summary: In summary, metformin may have potential benefits for pregnant women and newborns with no obvious adverse effects based on our review. However, further studies are still needed to provide evidence for the future use of metformin.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE (2021)

Review Medicine, General & Internal

Efficacy and safety of metformin in the treatment of gestational diabetes A protocol for systematic review and meta-analysis

Weirong Mao et al.

Summary: This study systematically investigated the efficacy and safety of metformin in the treatment of gestational diabetes, aiming to provide reliable evidence for its clinical application. Results from evaluating outcome indicators of pregnant women and newborn babies will contribute valuable insights for future research and clinical practice in managing gestational diabetes.

MEDICINE (2021)

Review Nutrition & Dietetics

Impacts of gut microbiota on gestational diabetes mellitus: a comprehensive review

Lingling Huang et al.

Summary: The alterations of gut microbiota, including changes in F/B ratio, SCFA-producing bacteria, bacteria with probiotics properties, and gram-negative LPS-producing bacteria, play a vital role in the development of GDM. Some studies have shown the beneficial effects of gut microbiota modification as a treatment for GDM, but further research is needed to fully understand the specific microbiota associated with GDM development and potentially identify novel diagnostic markers for early stages of the disease.

EUROPEAN JOURNAL OF NUTRITION (2021)

Article Cell Biology

Short chain fatty acids released by Fusobacterium nucleatum are neutrophil chemoattractants acting via free fatty acid receptor 2 (FFAR2)

Agnes Dahlstrand Rudin et al.

Summary: This study found that Fusobacterium nucleatum releases short chain fatty acids (SCFAs) like acetate and butyrate during its growth, which trigger chemotaxis of human neutrophils and cytosolic Ca2+ signals via free fatty acid receptor 2 (FFAR2). This discovery highlights the importance of the SCFA-FFAR2 interaction in recruiting neutrophils to the periodontal pocket, as well as its potential significance in the pathogenesis of other medical conditions involving colonization/infection of F. nucleatum.

CELLULAR MICROBIOLOGY (2021)

Article Multidisciplinary Sciences

Identification of mucin degraders of the human gut microbiota

Stefano Raimondi et al.

Summary: The study investigated gut mucin degraders of healthy subjects and found that various bacteria exhibited different metabolic capabilities and effects on the intestines when utilizing mucins.

SCIENTIFIC REPORTS (2021)

Article Biochemistry & Molecular Biology

Depletion of gut secretory immunoglobulin A coated Lactobacillus reuteri is associated with gestational diabetes mellitus-related intestinal mucosal barrier damage

Haowen Zhang et al.

Summary: The changes in SIgA coated bacteria from early to late pregnancy are associated with the development of gestational diabetes mellitus (GDM). SIgA coated beneficial gut bacteria, depleted in GDM, could serve as potential probiotics for GDM prevention. The increased intestinal mucosal damage and inflammation-induced dysbiosis of SIgA coated microbiota may be related to GDM, and SIgA coated L. reuteri can reduce LPS levels in GDM in vitro.

FOOD & FUNCTION (2021)

Article Biochemistry & Molecular Biology

Lactobacillus paracasei modulates the gut microbiota and improves inflammation in type 2 diabetic rats

Zhu Zeng et al.

Summary: The study showed that treatment with L. paracasei NL41 significantly improved the inflammatory status of T2D rats, reduced the levels of inflammatory markers, and protected gut barrier function. Furthermore, NL41 altered the gut microbiota structure and enriched beneficial microorganisms, indicating a close relationship between the amelioration of inflammation and key species of the gut microbiota.

FOOD & FUNCTION (2021)

Review Endocrinology & Metabolism

Zonulin as a potential putative biomarker of risk for shared type 1 diabetes and celiac disease autoimmunity

Lauren K. Wood Heickman et al.

DIABETES-METABOLISM RESEARCH AND REVIEWS (2020)

Review Immunology

Gut Microbiota and Gestational Diabetes Mellitus: A Review of Host-Gut Microbiota Interactions and Their Therapeutic Potential

Zubaidah Hasain et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)

Article Environmental Sciences

Correlation between Oral Glucose Tolerance Test Abnormalities and Adverse Pregnancy Outcomes in Gestational Diabetes: A Cross-Sectional Study

Aida Kalok et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020)

Article Endocrinology & Metabolism

Gestational diabetes: opportunities for improving maternal and child health

Ponnusamy Saravanan

LANCET DIABETES & ENDOCRINOLOGY (2020)

Article Gastroenterology & Hepatology

Leaky gut: mechanisms, measurement and clinical implications in humans

Michael Camilleri

Review Endocrinology & Metabolism

Metabolic effects of breastfeed in women with prior gestational diabetes mellitus: A systematic review and meta-analysis

Shujuan Ma et al.

DIABETES-METABOLISM RESEARCH AND REVIEWS (2019)

Article Biochemistry & Molecular Biology

Sterilized bifidobacteria suppressed fat accumulation and blood glucose level

Keita Kikuchi et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

Raptor regulates functional maturation of murine beta cells

Qicheng Ni et al.

NATURE COMMUNICATIONS (2017)

Article Biochemical Research Methods

DADA2: High-resolution sample inference from Illumina amplicon data

Benjamin J. Callahan et al.

NATURE METHODS (2016)

Article Microbiology

Faecalibaculum rodentium gen. nov., sp nov., isolated from the faeces of a laboratory mouse

Dong-Ho Chang et al.

ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY (2015)