Journal
VIRUSES-BASEL
Volume 14, Issue 11, Pages -Publisher
MDPI
DOI: 10.3390/v14112542
Keywords
hepatitis B virus; hepatitis B cure; implementation; public health; elimination; treatment; social impact; stigma
Categories
Funding
- Australian National Health and Medical Research Council
- University of Melbourne Faculty Trust Fellowship
- Gilead Sciences
- AbbVie
- Merck
- Burnet Institute
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Hepatitis B is a global health issue, and it is crucial to ensure that all patients have access to treatment. Eliminating viral hepatitis is vital for public health and requires addressing social and public health implications, as well as addressing current disparities and responding to cultural contexts and patient health needs.
Hepatitis B is a significant global health issue where the 296 million people estimated to live with the infection risk liver disease or cancer without clinical intervention. The World Health Organization has committed to eliminating viral hepatitis as a public health threat by 2030, with future curative hepatitis B interventions potentially revolutionizing public health responses to hepatitis B, and being essential for viral hepatitis elimination. Understanding the social and public health implications of any cure is imperative for its successful implementation. This exploratory research, using semi-structured qualitative interviews with a broad range of professional stakeholders identifies the public health elements needed to ensure that a hepatitis B cure can be accessed by all people with hepatitis B. Issues highlighted by the experience of hepatitis C cure access include preparatory work to reorientate policy settings, develop resourcing options, and the appropriateness of health service delivery models. While the form and complexity of curative hepatitis B interventions are to be determined, addressing current disparities in cascade of care figures is imperative with implementation models needing to respond to the cultural contexts, social implications, and health needs of people with hepatitis B, with cure endpoints and discourse being contested.
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