Journal
CELL BIOLOGY AND TOXICOLOGY
Volume 31, Issue 6, Pages 273-283Publisher
SPRINGER
DOI: 10.1007/s10565-015-9310-0
Keywords
Behavioral tests; Cadmium; Lectins; Toxicity; Ultrastructure; Ucrit
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Funding
- NIEHS NIH HHS [R01 ES010563, P30 ES000267] Funding Source: Medline
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This report describes the alterations induced by an environmentally realistic concentration of cadmium in skeletal muscle fibre organization, composition, and function in the teleost zebrafish. Results demonstrate that the ion induces a significant quantitative and qualitative deterioration, disrupting sarcomeric pattern and altering glycoprotein composition. These events, together with a mitochondrial damage, result in a significant reduction in swimming performance. In conclusion, the evidence here collected indicate that in presence of an environmental cadmium contamination, important economic (yields in fisheries/aquaculture), consumer health (fish is an important source of proteins), and ecological (reduced fitness due to reduced swimming performance) consequences can be expected.
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