4.5 Letter

Letter to editor regarding a review of MF59-adjuvanted influenza vaccine by Gartner et al

Related references

Note: Only part of the references are listed.
Review Immunology

Importance and value of adjuvanted influenza vaccine in the care of older adults from a European perspective-A systematic review of recently published literature on real-world data

B. C. Gaertner et al.

Summary: The study suggests that both adjuvanted and high-dose vaccines are effective alternatives for vaccination programs in older adults and preferable over conventional standard-dose vaccines.

VACCINE (2022)

Article Infectious Diseases

Prevention of influenza during mismatched seasons in older adults with an MF59-adjuvanted quadrivalent influenza vaccine: a randomised, controlled, multicentre, phase 3 efficacy study

Jiri Beran et al.

Summary: The study aimed to investigate the clinical efficacy of MF59-adjuvanted quadrivalent influenza vaccine in adults aged 65 and older. The vaccine efficacy was higher against influenza cases associated with higher fever, but did not meet the preset standard in seasons with high amounts of vaccine strain mismatch.

LANCET INFECTIOUS DISEASES (2021)

Review Infectious Diseases

Effectiveness of the MF59-adjuvanted trivalent or quadrivalent seasonal influenza vaccine among adults 65 years of age or older, a systematic review and meta-analysis

Brenda L. Coleman et al.

Summary: The study found that the seasonal MF59-adjuvanted trivalent/quadrivalent influenza vaccine significantly reduced the medical encounters due to lab-confirmed influenza among adults aged 65 and older, compared to no vaccination or vaccination with standard or high-dose egg-based influenza vaccines.

INFLUENZA AND OTHER RESPIRATORY VIRUSES (2021)