Cross-kingdom RNAi to enhance the efficacy of insect pathogens

Insect pathogens play significant roles in the biocontrol of medical and agricultural pests. Cui et al. demonstrated that genetically modified (GM) fungi expressing host mosquito miRNAs could enhance the efficacy of the fungus by suppressing the host immune response. This opens avenues for utilisation of cross-kingdom RNAi in biocontrol.

Automated summary

Insect pathogens are crucial in controlling medical and agricultural pests. Cui et al. found that genetically modified fungi, expressing host mosquito miRNAs, can enhance the fungus's efficacy by suppressing the host immune response. This discovery paves the way for the utilization of cross-kingdom RNA interference in biocontrol.