☆ 4.6 Review

Lymph node lymphatic endothelial cells as multifaceted gatekeepers in the immune system

TRENDS IN IMMUNOLOGY (2023)

Related references

Note: Only part of the references are listed.
Review Oncology

The lymphatic system and sentinel lymph nodes: conduit for cancer metastasis

Stanley P. Leong et al.

Summary: The lymphatic system is a complex system composed of lymphatic vessels and lymph nodes. It functions to drain extracellular fluid containing cellular debris, excess water, and toxins to the circulatory system. Lymph nodes act as filters to ensure the sterility of the lymph fluid returning to the heart. Through this system, cancer cells can enter lymphatic vessels and nodes.

CLINICAL & EXPERIMENTAL METASTASIS (2022)

Add to Collection
Article Cell Biology

Melanoma-derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes

Noelle Leary et al.

Summary: EV-mediated communication between melanoma and lymph node endothelial cells is identified as a new pathway involved in tumor progression and immune inhibition. These extracellular vesicles are transported rapidly to lymph nodes through lymphatic vessels and interact with endothelial cells and macrophages.

JOURNAL OF EXTRACELLULAR VESICLES (2022)

Add to Collection
Article Immunology

Fate mapping and scRNA sequencing reveal origin and diversity of lymph node stromal precursors

Elisa Lenti et al.

Summary: This study identifies the origin and composition of lymph node stromal and endothelial cells through lineage tracing and single-cell transcriptome analysis. The results show that stromal and endothelial cells originate from different cell populations in the embryo. Single-cell RNA sequencing reveals different subsets of stromal cells and suggests the presence of proliferating progenitors in embryonic lymph nodes.

IMMUNITY (2022)

Add to Collection
Review Medicine, Research & Experimental

Utilization of Vascular Endothelial Growth Factor-C156S in Therapeutic Lymphangiogenesis: A Systematic Review

Antonio J. Forte et al.

Summary: VEGF-C156S is a potential growth factor for lymphangiogenesis, but its effectiveness and safety in lymphedema treatment need further investigation.

LYMPHATIC RESEARCH AND BIOLOGY (2022)

Add to Collection
Article Cell Biology

A single-cell atlas of non-haematopoietic cells in human lymph nodes and lymphoma reveals a landscape of stromal remodelling

Yoshiaki Abe et al.

Summary: This study constructed a single-cell transcriptome atlas of non-haematopoietic cells (NHCs), including mesenchymal stromal cells and endothelial cells, collected from human samples. The atlas revealed 30 distinct subclusters of NHCs, including previously unrecognized ones. Comparative analyses with lymphoma NHCs showed subcluster-specific changes in gene expression and interaction with malignant cells in follicular lymphoma NHCs, providing insights into stromal remodelling in lymphoma and potential clinical biomarkers. The study updates NHC taxonomy in human lymph nodes and provides a rich resource for advancing lymphoma management and therapy.

NATURE CELL BIOLOGY (2022)

Add to Collection
Article Multidisciplinary Sciences

Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift

Yang Zhang et al.

Summary: This study demonstrates that memory B cells can recycle back to germinal centers via CCL-21 mediated chemotaxis to transport antigens, potentially contributing to affinity maturation and antigenic drift.

NATURE COMMUNICATIONS (2022)

Add to Collection
Review Pharmacology & Pharmacy

ATP and Adenosine Metabolism in Cancer: Exploitation for Therapeutic Gain

Gennady G. Yegutkin et al.

Summary: Adenosine pathway plays an important role in tumor immunomodulation and cell proliferation. Tumors create an adenosine-rich microenvironment by releasing ATP and converting it into adenosine. There are multiple pathways controlling intratumoral adenosine levels that need to be considered for more effective therapeutic approaches. This review provides a comprehensive view of adenosine metabolism and its role in cancer immunosurveillance and tumor angiogenesis.

PHARMACOLOGICAL REVIEWS (2022)

Add to Collection
Article Multidisciplinary Sciences

IFN-γ–dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis

Laure Garnier et al.

Science Advances (2022)

Add to Collection
Article Oncology

Immunomodulatory Responses of Subcapsular Sinus Floor Lymphatic Endothelial Cells in Tumor-Draining Lymph Nodes

Eliane Sibler et al.

Summary: Lymphatic endothelial cells (LECs) in tumor-draining lymph nodes (LNs) play a role in tumor immune response, particularly a specific subset of LECs with upregulated genes, including podoplanin, which mediate macrophage adhesion. Deletion of podoplanin in tumor-draining LNs leads to a decrease in macrophage numbers.

CANCERS (2022)

Add to Collection
Article Immunology

CD73 contributes to anti-inflammatory properties of afferent lymphatic endothelial cells in humans and mice

Dominik Eichin et al.

Summary: CD73 plays an unknown role in dampening immune responses on afferent lymphatics, as revealed by this study. Knocking out or suppressing CD73 leads to upregulation of inflammation-associated genes on lymphatic endothelial cells and a more pro-inflammatory phenotype of interacting dendritic cells in vitro and in vivo. Anti-CD73 antibodies have negligible effects on gene expression of lymphatic- and blood-endothelial cells, indicating a low likelihood of endothelial cell-related adverse effects with CD73 targeting therapeutic antibodies.

EUROPEAN JOURNAL OF IMMUNOLOGY (2021)

Add to Collection
Article Biochemistry & Molecular Biology

Lymph nodes are innervated by a unique population of sensory neurons with immunomodulatory potential

Siyi Huang et al.

Summary: The study found that peptidergic nociceptors, a subset of sensory neurons, innervate LNs, distinct from other sensory neurons surrounding the skin. Optogenetic stimulation of LN-innervating sensory fibers triggers rapid transcriptional changes in interacting cell types, particularly endothelium, stromal cells, and innate leukocytes.

CELL (2021)

Add to Collection
Review Immunology

Development and Immunological Function of Lymph Node Stromal Cells

Natalia Barbara Pikor et al.

Summary: Stromal cells in lymph nodes play a crucial role in supporting immune cell interactions by providing a tailored mixture of niche factors. Recent advances in genetic models and transcriptomic analyses have revealed the strategic positioning of distinct stromal cell subsets for efficient immune responses. Activation of poised stromal cell-supported niches, rather than differentiation of new subsets, governs the interaction of immune cells during adaptive immune responses.

JOURNAL OF IMMUNOLOGY (2021)

Add to Collection
Article Biochemistry & Molecular Biology

MARCO+ lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination

Kathryn S. Carpentier et al.

Summary: The scavenger receptor MARCO plays critical roles in controlling viremia during arthritogenic alphavirus infections in mice, limiting viral spread to the bloodstream and clearing alphavirus particles from the circulation. This defense mechanism reduces viral tissue burdens and severity of disease, highlighting the importance of MARCO in viremia control.

EMBO JOURNAL (2021)

Add to Collection
Article Immunology

Lymphatic Endothelial Cell Activation and Dendritic Cell Transmigration Is Modified by Genetic Deletion of Clever-1

Sina Tadayon et al.

Summary: Clever-1, a molecule expressed on certain macrophages and lymphatic endothelial cells, plays a role in regulating DC trafficking and immune responses. Despite hindering DC entry into lymphatics, Clever-1 knockout mice showed increased MHC II expression on DCs and less tolerogenic LEC phenotype in lymph nodes, leading to stronger antigen-specific immune responses. This suggests that Clever-1 facilitates immunosuppressive interactions with migrating DCs, modulating immune responses in the draining lymph nodes.

FRONTIERS IN IMMUNOLOGY (2021)

Add to Collection
Article Immunology

Macroautophagy in lymphatic endothelial cells inhibits T cell-mediated autoimmunity

Guillaume Harle et al.

Summary: The study reveals that autophagy in LECs plays a crucial role in modulating T cell activation in arthritis, potentially affecting T reg cell populations and S1P production to influence the migration of pathogenic T cells and inflammation development.

JOURNAL OF EXPERIMENTAL MEDICINE (2021)

Add to Collection
Article Multidisciplinary Sciences

Scavenging of soluble and immobilized CCL21 by ACKR4 regulates peripheral dendritic cell emigration

Cameron R. Bastow et al.

Summary: This study reveals the mechanism by which ACKR4 controls DC migration in barrier tissues, identifying the existence of two forms of CCL21 in steady-state conditions and their regulation by ACKR4. It enhances understanding of functional chemokine gradient formation by showing how ACKR4 affects CCL21 gradients in barrier tissues and downstream lymph nodes.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Add to Collection
Article Biology

Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node

Shannon M. Walsh et al.

Summary: Traditional techniques for detecting foreign antigens in vivo have limitations, prompting the development of a "molecular tracking device" to better study the distribution and retention of antigens in lymph nodes. By utilizing an antigen conjugated to a nuclease-resistant DNA tag and single-cell mRNA sequencing, antigen abundance in lymph nodes can be quantified. This advancement enables new approaches to study the dissemination of antigen-adjuvant conjugates and to identify mechanisms of antigen acquisition and retention at a cellular level in vivo.

ELIFE (2021)

Add to Collection
Article Oncology

Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses

Nikola Cousin et al.

Summary: A new study using a lymphatic-specific PD-L1 knockout mouse model reveals that lymphatic endothelial PD-L1 expression reduces tumor immunity by inducing apoptosis in tumor-specific CD8(+) central memory cells in tumor-draining lymph nodes.

CANCER RESEARCH (2021)

Add to Collection
Article Oncology

Systemic Blockade of Clever-1 Elicits Lymphocyte Activation Alongside Checkpoint Molecule Downregulation in Patients with Solid Tumors: Results from a Phase I/II Clinical Trial

Reetta Virtakoivu et al.

Summary: The study revealed the unique role of the Clever-1 receptor in suppressing adaptive immune cells in the tumor microenvironment, suggesting that targeting this receptor may promote intratumoral proinflammatory responses and have potential therapeutic effects for patients with metastatic cancer.

CLINICAL CANCER RESEARCH (2021)

Add to Collection
Article Multidisciplinary Sciences

Cells of the human intestinal tract mapped across space and time

Rasa Elmentaite et al.

Summary: The study analyzes cells from various stages of human development along the intestinal tract, revealing transcriptionally distinct BEST4 epithelial cells and implicating IgG sensing as a function of tuft cells. It also describes neural cell populations in the developing enteric nervous system and identifies key players in the formation of lymphoid tissue in early human development and inflammatory bowel disease.

NATURE (2021)

Add to Collection
Review Immunology

Lymph node stromal cells: subsets and functions in health and disease

C. Grasso et al.

Summary: Lymph nodes stromal cells are crucial for guiding adaptive immune responses, with recent advancements in single-cell technologies revealing significant heterogeneity among subsets. While most knowledge comes from mouse studies, some similarities with human counterparts suggest their importance.

TRENDS IN IMMUNOLOGY (2021)

Add to Collection
Review Immunology

Communication, construction, and fluid control: lymphoid organ fibroblastic reticular cell and conduit networks

Sophie E. Acton et al.

Summary: This article discusses the crucial role of fibroblastic reticular cells in secondary lymphoid organs, focusing on their importance in immune cell interactions and lymphocyte activation and differentiation. The generation of conduit system by FRCs plays a key role in controlling fluid and immune cell movement in secondary lymphoid organs.

TRENDS IN IMMUNOLOGY (2021)

Add to Collection
Article Cell Biology

Single-Cell Transcriptional Heterogeneity of Lymphatic Endothelial Cells in Normal and Inflamed Murine Lymph Nodes

Eliane Sibler et al.

Summary: The study used single-cell RNA sequencing to investigate transcriptional changes in lymphatic endothelial cells in lymph nodes draining naive and inflamed skin. It was found that subsets of these cells responded individually to skin inflammation, suggesting distinct functions under pathological conditions. Dysregulated genes during inflammation were identified, including an up-regulation of CD200, potentially involved in immune regulation. Additionally, in silico analysis predicted interactions of these cells with diverse immune cells in the lymph nodes, showing similarities in transcriptional changes in different skin inflammation settings.

CELLS (2021)

Add to Collection
Article Cell Biology

Lymph-Derived Neutrophils Primarily Locate to the Subcapsular and Medullary Sinuses in Resting and Inflamed Lymph Nodes

Jenny de Castro Pinho et al.

Summary: Neutrophils primarily localize in the subcapsular and medullary sinuses of lymph nodes, with resting and in vitro-activated neutrophils showing random migration within the medulla. Co-injected dendritic cells facilitate the entry of resting neutrophils into the lymph node parenchyma via the subcapsular sinus, while in vivo-activated adoptively transferred neutrophils migrate into the interfollicular areas of the lymph node.

CELLS (2021)

Add to Collection
Review Cell Biology

Structure and Immune Function of Afferent Lymphatics and Their Mechanistic Contribution to Dendritic Cell and T Cell Trafficking

Jorge Arasa et al.

Summary: Afferent lymphatic vessels serve as immunologic communication highways between peripheral tissues and lymph nodes, facilitating the migration of dendritic cells (DCs) and T cells for immune surveillance. Recent studies show that DCs and T cells actively interact and patrol within lymphatic vessels before passively transported to draining lymph nodes, shedding light on the mechanisms of lymphatic migration.

CELLS (2021)

Add to Collection
Article Oncology

Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism

Susana Garcia-Silva et al.

Summary: Peinado and colleagues demonstrate that melanoma-secreted small extracellular vesicles (sEVs) and NGFR cargo can induce lymphangiogenesis and promote lymph node pre-metastatic niche formation, facilitating melanoma metastasis. Targeting NGFR could potentially prevent this process in pre-clinical settings.

NATURE CANCER (2021)

Add to Collection
Review Pathology

The Multifaceted Effects of Breast Cancer on Tumor Nodes

Samir Jana et al.

Summary: This review provides an overview of how breast cancer cells modulate LN stromal and hematopoietic cells to promote metastasis and immune evasion, emphasizing the association between breast cancer and lymph node metastasis, as well as the immune response against breast cancer.

AMERICAN JOURNAL OF PATHOLOGY (2021)

Add to Collection
Article Immunology

Robo4 contributes to the turnover of Peyer's patch B cells

Ruth Fair-Makela et al.

MUCOSAL IMMUNOLOGY (2020)

Add to Collection
Article Multidisciplinary Sciences

Lymphatic endothelial cells prime naive CD8+ T cells into memory cells under steady-state conditions

Efthymia Vokali et al.

NATURE COMMUNICATIONS (2020)

Add to Collection
Article Multidisciplinary Sciences

Efficient homing of T cells via afferent lymphatics requires mechanical arrest and integrin-supported chemokine guidance

Rieke Martens et al.

NATURE COMMUNICATIONS (2020)

Add to Collection
Article Immunology

Neutrophils Recirculate through Lymph Nodes to Survey Tissues for Pathogens

Ania Bogoslowski et al.

JOURNAL OF IMMUNOLOGY (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes

Noriki Fujimoto et al.

PLOS BIOLOGY (2020)

Add to Collection
Review Immunology

Lymph node stromal cells: cartographers of the immune system

Akshay T. Krishnamurty et al.

NATURE IMMUNOLOGY (2020)

Add to Collection
Review Biochemistry & Molecular Biology

The Lymphatic Vasculature in the 21st Century: Novel Functional Roles in Homeostasis and Disease

Guillermo Oliver et al.

CELL (2020)

Add to Collection
Article Medicine, Research & Experimental

Mycobacterium tuberculosis cords within lymphatic endothelial cells to evade host immunity

Thomas R. Lerner et al.

JCI INSIGHT (2020)

Add to Collection
Article Cardiac & Cardiovascular Systems

A Single-Cell Transcriptional Roadmap of the Mouse and Human Lymph Node Lymphatic Vasculature

Menglan Xiang et al.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2020)

Add to Collection
Review Multidisciplinary Sciences

Biological functions of lymphatic vessels

Tatiana V. Petrova et al.

SCIENCE (2020)

Add to Collection
Article Multidisciplinary Sciences

Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection

Matthew K. Siggins et al.

NATURE COMMUNICATIONS (2020)

Add to Collection
Article Biology

EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity

Maike Frye et al.

ELIFE (2020)

Add to Collection
Review Immunology

Lymphatic endothelial cells of the lymph node

Sirpa Jalkanen et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Add to Collection
Article Oncology

Colorectal cancer exosomes induce lymphatic network remodeling in lymph nodes

Bo Sun et al.

INTERNATIONAL JOURNAL OF CANCER (2019)

Add to Collection
Article Immunology

Lymph node conduits transport virions for rapid T cell activation

Glennys V. Reynoso et al.

NATURE IMMUNOLOGY (2019)

Add to Collection
Review Oncology

Vessel co-option in cancer

Elizabeth A. Kuczynski et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2019)

Add to Collection
Review Cell Biology

Exosome-Mediated Metastasis: Communication from a Distance

Inbal Wortzel et al.

DEVELOPMENTAL CELL (2019)

Add to Collection
Article Immunology

Lymphatic Endothelial Cells Are Essential Components of the Subcapsular Sinus Macrophage Niche

Isabelle Mondor et al.

IMMUNITY (2019)

Add to Collection
Review Immunology

Chemokines and other mediators in the development and functional organization of lymph nodes

Nadine Eckert et al.

IMMUNOLOGICAL REVIEWS (2019)

Add to Collection
Article Immunology

Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients

Maria A. S. Broggi et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2019)

Add to Collection
Article Immunology

Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche

Abdouramane Camara et al.

IMMUNITY (2019)

Add to Collection
Article Medicine, Research & Experimental

Transcytosis route mediates rapid delivery of intact antibodies to draining lymph nodes

Laura Kahari et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Add to Collection
Article Immunology

Comparative Transcriptomic Analysis Identifies a Range of Immunologically Related Functional Elaborations of Lymph Node Associated Lymphatic and Blood Endothelial Cells

Stella J. Berendam et al.

FRONTIERS IN IMMUNOLOGY (2019)

Add to Collection
Article Pathology

Myeloid-Derived Lymphatic Endothelial Cell Progenitors Significantly Contribute to Lymphatic Metastasis in Clinical Breast Cancer

Lisa Volk-Draper et al.

AMERICAN JOURNAL OF PATHOLOGY (2019)

Add to Collection
Article Immunology

Single-Cell Survey of Human Lymphatics Unveils Marked Endothelial Cell Heterogeneity and Mechanisms of Homing for Neutrophils

Akira Takeda et al.

IMMUNITY (2019)

Add to Collection
Article Multidisciplinary Sciences

Phenotypically distinct neutrophils patrol uninfected human and mouse lymph nodes

Laurence S. C. Lok et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Add to Collection
Editorial Material Clinical Neurology

Another sphingosine 1-phosphate receptor modulator for the treatment of patients with multiple sclerosis

Ellen M. Mowry et al.

LANCET NEUROLOGY (2019)

Add to Collection
Article Biology

Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses

Kathryn S. Carpentier et al.

ELIFE (2019)

Add to Collection
Review Immunology

Subcapsular Sinus Macrophages: The Seat of Innate and Adaptive Memory in Murine Lymph Nodes

Imogen Moran et al.

TRENDS IN IMMUNOLOGY (2019)

Add to Collection
Review Immunology

Lymph Node Lymphatic Endothelial Cell Expansion and Contraction and the Programming of the Immune Response

Erin D. Lucas et al.

FRONTIERS IN IMMUNOLOGY (2019)

Add to Collection
Review Immunology

Leucocyte Trafficking via the Lymphatic Vasculature - Mechanisms and Consequences

David G. Jackson

FRONTIERS IN IMMUNOLOGY (2019)

Add to Collection
Article Immunology

Type 1 IFN and PD-L1 Coordinate Lymphatic Endothelial Cell Expansion and Contraction during an Inflammatory Immune Response

Erin D. Lucas et al.

JOURNAL OF IMMUNOLOGY (2018)

Add to Collection
Article Multidisciplinary Sciences

Quantitative Profiling of the Lymph Node Clearance Capacity

Cristina C. Clement et al.

SCIENTIFIC REPORTS (2018)

Add to Collection
Article Immunology

Multiple roles of lymphatic vessels in peripheral lymph node development

Esther Bovay et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2018)

Add to Collection
Article Immunology

Dendritic cell and antigen dispersal landscapes regulate T cell immunity

Michael Y. Gerner et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Add to Collection
Review Immunology

The lymph node neutrophil

Henry R. Hampton et al.

SEMINARS IN IMMUNOLOGY (2016)

Add to Collection
Review Immunology

Lymph formation, composition and circulation: a proteomics perspective

Kirk C. Hansen et al.

INTERNATIONAL IMMUNOLOGY (2015)

Add to Collection
Article Immunology

The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes

Pia Rantakari et al.

NATURE IMMUNOLOGY (2015)

Add to Collection
Article Immunology

The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes

Maria H. Ulvmar et al.

NATURE IMMUNOLOGY (2014)

Add to Collection
Article Multidisciplinary Sciences

Antigen capture and archiving by lymphatic endothelial cells following vaccination or viral infection

Beth A. Tamburini et al.

NATURE COMMUNICATIONS (2014)

Add to Collection
Article Hematology

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

Eric F. Tewalt et al.

BLOOD (2012)

Add to Collection
Article Developmental Biology

Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax

John D. Kanady et al.

DEVELOPMENTAL BIOLOGY (2011)

Add to Collection
Article Immunology

Afferent lymph-derived T cells and DCs use different chemokine receptor CCR7-dependent routes for entry into the lymph node and intranodal migration

Asolina Braun et al.

NATURE IMMUNOLOGY (2011)

Add to Collection
Review Anatomy & Morphology

The Lymph Node Revisited: Development, Morphology, Functioning, and Role in Triggering Primary Immune Responses

Guy Sainte-Marie

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2010)

Add to Collection
Article Cell Biology

Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3

Yunling Xu et al.

JOURNAL OF CELL BIOLOGY (2010)

Add to Collection
Article Cell Biology

Integrin-α9 Is Required for Fibronectin Matrix Assembly during Lymphatic Valve Morphogenesis

Eleni Bazigou et al.

DEVELOPMENTAL CELL (2009)

Add to Collection
Article Immunology

Conduits Mediate Transport of Low-Molecular-Weight Antigen to Lymph Node Follicles

Ramon Roozendaal et al.

IMMUNITY (2009)

Add to Collection
Article Immunology

Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells

Tri Giang Phan et al.

NATURE IMMUNOLOGY (2007)

Add to Collection
Article Biochemical Research Methods

Anatomy and nomenclature of murine lymph nodes: Descriptive study and nomenclatory standardization in BALB/cAnNCr1 mice

W Van den Broeck et al.

JOURNAL OF IMMUNOLOGICAL METHODS (2006)

Add to Collection
Article Immunology

Lymph, lymphocytes, and lymphatics

B. Ristevski et al.

IMMUNOLOGIC RESEARCH (2006)

Add to Collection
Article Pathology

Normal structure, function, and histology of lymph nodes

Cynthia L. Willard-Mack

TOXICOLOGIC PATHOLOGY (2006)

Add to Collection
Article Biochemistry & Molecular Biology

The transcription factor Prox1 is a marker for lymphatic endothelial cells in normal and diseased human tissues

J Wilting et al.

FASEB JOURNAL (2002)

Add to Collection
Article Immunology

Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex

JE Gretz et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2000)

Add to Collection
Webinars Posters Questions Hubs Funding Journals Papers Connect Collections Reviewers About Us FAQs Mobile App Privacy Policy Terms of Use
© Peeref 2019-2024. All rights reserved.