Recent trends and advancements in electrochemiluminescence biosensors for human virus detection

Researchers are constantly looking to find new techniques of virus detection that are sensitive, cost-effective, and accurate. Additionally, they can be used as a point-of-care (POC) tool due to the fact that the populace is growing at a quick tempo, and epidemics are materializing greater often than ever. Electrochemiluminescence-based (ECL) biosensors for the detection of viruses have become one of the most quickly developing sensors in this field. Thus, we here focus on recent trends and developments of these sensors with regard to virus detection. Also, quantitative analysis of various viruses (e.g., Influenza virus, SARS-CoV-2, HIV, HPV, Hepatitis virus, and Zika virus) with a specific interest in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was introduced from the perspective of the biomarker and the biological receptor immobilized on the ECL-based sensors, such as nucleic acids -based, immunosensors, and other affinity ECL biosensors. (c) 2022 Elsevier B.V. All rights reserved.

Automated summary

Electrochemiluminescence-based biosensors are sensitive, cost-effective, and accurate techniques for virus detection. This article focuses on the recent trends and developments of these sensors in the field of virus detection, and introduces quantitative analysis of various viruses using specific biomarkers and biological receptors immobilized on ECL-based sensors.