4.1 Article

Effect of the Reelin-Dab1 signaling pathway on the abnormal metabolism of Aβ protein induced by aluminum

Related references

Note: Only part of the references are listed.
Article Environmental Sciences

Benthic-pelagic mixing of trace elements in estuarine food webs

Kaitlyn O'Mara et al.

Summary: Trace element accumulation pathways play a crucial role in ecological and toxicological studies on aquatic organisms. The study highlights the influence of diet and environment on trace element composition in estuarine food webs, showing how food sources and ecology affect the concentration of elements within species.

MARINE ENVIRONMENTAL RESEARCH (2022)

Editorial Material Cell Biology

Evaluation of suprachiasmatic nucleus in Alzheimer's disease with non-invasive magnetic resonance methods

Rico Singer et al.

NEURAL REGENERATION RESEARCH (2022)

Article Biochemistry & Molecular Biology

Neurodegenerative and Hepatorenal Disorders Induced Via Aluminum Chloride in Murine System: Impact of β-Secretase, MAPK, and KIM

Sohair Aly Hassan et al.

Summary: This study revealed significant biochemical alterations induced by AlCl3 in the brain, liver, and kidney, including oxidative damage and changes in protein expressions, which may contribute to the development of various diseases.

BIOLOGICAL TRACE ELEMENT RESEARCH (2021)

Article Clinical Neurology

The apolipoprotein receptor LRP3 compromises APP levels

Inmaculada Cuchillo-Ibanez et al.

Summary: The study indicates that ApoER2/reelin signaling regulates LRP3 expression, which is affected in AD; LRP3 is involved in regulating APP levels.

ALZHEIMERS RESEARCH & THERAPY (2021)

Review Cell Biology

Re-emphasizing early Alzheimer's disease pathology starting in select entorhinal neurons, with a special focus on mitophagy

Asgeir Kobro-Flatmoen et al.

Summary: The entorhinal-hippocampal system plays a crucial role in declarative memory, but is vulnerable to changes in aging and pathological processes, especially in Alzheimer's disease. Mitochondrial dysfunction in reelin-positive EC layer II neurons appears to be an important factor in the formation of neurofibrillary tangles. More research on these interactions could lead to new insights on AD etiology and potential drug development.

AGEING RESEARCH REVIEWS (2021)

Review Chemistry, Physical

Selective Laser Melting of Al-Based Matrix Composites with Al2O3 Reinforcement: Features and Advantages

Ivan A. Pelevin et al.

Summary: This review discusses the application of selective laser melting (SLM) in the fabrication of aluminum matrix composites (AMCs) with alumina reinforcement. The study shows that achieving homogeneous distribution of reinforcing particles and optimizing SLM parameters can lead to improved density, hardness, and tribological properties of the materials.

MATERIALS (2021)

Article Biochemistry & Molecular Biology

Alleviation of Memory Deficit by Bergenin via the Regulation of Reelin and Nrf-2/NF-κB Pathway in Transgenic Mouse Model

Bushra Shal et al.

Summary: This study demonstrated the neuroprotective and anti-inflammatory effects of Bergenin in cell experiments and a mouse model, alleviating spatial memory deficits associated with neurodegeneration. Bergenin modulates multiple signaling pathways, including enhancing Reelin signaling, inhibiting Aβ aggregation, and increasing antioxidant levels, making it a potential drug candidate for treating neurodegenerative diseases.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Cell Biology

Neuro-amelioration of cinnamaldehyde in aluminum-induced Alzheimer's disease rat model

Hesham N. Mustafa

JOURNAL OF HISTOTECHNOLOGY (2020)

Article Pharmacology & Pharmacy

A Computational Study of Natural Compounds from Bacopa monnieri in the Treatment of Alzheimer's Disease

Qazi M. S. Jamal et al.

CURRENT PHARMACEUTICAL DESIGN (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

Brain18F-FDG PET analysis via interval-valued reconstruction: proof of concept for Alzheimer's disease diagnosis

Florentin Kucharczak et al.

ANNALS OF NUCLEAR MEDICINE (2020)

Article Neurosciences

Maximizing Safety in the Conduct of Alzheimer's Disease Fluid Biomarker Research in the Era of COVID-19

Suzanne E. Schindler et al.

JOURNAL OF ALZHEIMERS DISEASE (2020)

Article Clinical Neurology

IL-8 and MCP-1 Impact on Tau Phosphorylation and Phosphatase Activity

Margarida Vaz et al.

CURRENT ALZHEIMER RESEARCH (2020)

Article Neurosciences

Aluminum in Neurological and Neurodegenerative Disease

Donald R. C. McLachlan et al.

MOLECULAR NEUROBIOLOGY (2019)

Article Biochemistry & Molecular Biology

Decreased generation of C-terminal fragments of ApoER2 and increased reelin expression in Alzheimer's disease

Trinidad Mata-Balaguer et al.

FASEB JOURNAL (2018)

Article Multidisciplinary Sciences

Reelin transiently promotes N-cadherin-dependent neuronal adhesion during mouse cortical development

Yuki Matsunaga et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Clinical Neurology

The effects of different familial Alzheimer's disease mutations on APP processing in vivo

Steinunn Thordardottir et al.

ALZHEIMERS RESEARCH & THERAPY (2017)

Article Clinical Neurology

2016 Alzheimer's disease facts and figures

Alzheimers & Dementia (2016)

Review Chemistry, Medicinal

Neurodegenerative diseases linked to misfolded proteins and their therapeutic approaches: A review

Hena Khanam et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)

Review Pharmacology & Pharmacy

APP Receptor? To Be or Not To Be

Carole Deyts et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2016)

Article Biochemistry & Molecular Biology

Reelin protects against amyloid β toxicity in vivo

Courtney Lane-Donovan et al.

SCIENCE SIGNALING (2015)

Article Biochemistry & Molecular Biology

Reelin protects against amyloid β toxicity in vivo

Courtney Lane-Donovan et al.

SCIENCE SIGNALING (2015)

Article Biochemistry & Molecular Biology

Occupational exposure to aluminum and its amyloidogenic link with cognitive functions

N. H. Zawilla et al.

JOURNAL OF INORGANIC BIOCHEMISTRY (2014)

Article Public, Environmental & Occupational Health

Cognitive Disorders and Tau-Protein Expression Among Retired Aluminum Smelting Workers

Xiaoting Lu et al.

JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2014)

Review Neurosciences

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer's Disease

Tara L. Spires-Jones et al.

NEURON (2014)

Article Multidisciplinary Sciences

Beta-Amyloid Impairs Reelin Signaling

Inmaculada Cuchillo-Ibanez et al.

PLOS ONE (2013)

Review Cell Biology

Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease

Maria-Paz Marzolo et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2009)

Article Neurosciences

Reelin modulates NMDA receptor activity in cortical neurons

Y Chen et al.

JOURNAL OF NEUROSCIENCE (2005)

Article Public, Environmental & Occupational Health

Body burden of aluminum in relation to central nervous system function among metal inert-gas welders

V Riihimäki et al.

SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH (2000)