Validation of combined carcinoembryonic antigen and glucose testing in pancreatic cyst fluid to differentiate mucinous from non-mucinous cysts

Article Medical Laboratory Technology

Co-analysis of pancreatic cyst fluid carcinoembryonic antigen and glucose with novel cut-off levels better distinguishes between mucinous and non-mucinous neoplastic pancreatic cystic lesions

Burcu Barutcuoglu et al.

Summary: Analysis of cyst fluid showed that higher levels of CEA and CA 19-9, and lower levels of glucose, were effective indicators for distinguishing mucinous from non-mucinous neoplastic pancreatic cystic lesions. Co-analysis of CEA and glucose had the best testing performance for diagnosing mucinous neoplastic PCLs, while adding value to prediction for ruling out mucinous PCLs.

ANNALS OF CLINICAL BIOCHEMISTRY (2022)

Add to Collection

Review Gastroenterology & Hepatology

Intracystic Glucose Levels in Differentiating Mucinous From Nonmucinous Pancreatic Cysts A Systematic Review and Meta-analysis

Babu P. Mohan et al.

Summary: The study demonstrates that intracystic glucose levels in fluid samples collected by endoscopic ultrasound guided fine-needle aspiration can accurately differentiate mucinous pancreatic cysts from nonmucinous cysts, with a cut-off of 50mg/dL showing the best performance.

JOURNAL OF CLINICAL GASTROENTEROLOGY (2022)

Add to Collection

Review Gastroenterology & Hepatology

Molecular analysis of EUS-acquired pancreatic cyst fluid for KRAS and GNAS mutations for diagnosis of intraductal papillary mucinous neoplasia and mucinous cystic lesions: a systematic review and meta-analysis

Thomas R. McCarty et al.

Summary: The molecular analysis of KRAS and GNAS mutations in EUS-acquired pancreatic cyst fluid shows high sensitivity and specificity, significantly improving diagnostic accuracy for IPMNs and MCLs compared to using CEA alone.

GASTROINTESTINAL ENDOSCOPY (2021)

Add to Collection

Review Gastroenterology & Hepatology