4.7 Article

Single-atom Rh nanozyme: An efficient catalyst for highly sensitive colorimetric detection of acetylcholinesterase activity and adrenaline

Related references

Note: Only part of the references are listed.
Article Chemistry, Analytical

Peroxidase-like activity of Ru-N-C nanozymes in colorimetric assay of acetylcholinesterase activity

Bingsong Yan et al.

Summary: In this study, Ru-N-C nanozymes with abundant active sites were prepared by pyrolyzing Ru(acac)(3) trapped zeolitic-imidazolate-frameworks (Ru(acac)(3)@ZIF-8). A novel biosensing system with explicit mechanism was strategically fabricated for sensitively determining acetylcholinesterase (AChE) and tacrine, showing great potential in real matrix applications. Additionally, INH and IMPLICATION-AND logic gates were rationally constructed based on the proposed colorimetric sensor, providing a sustainable and effective avenue for developing novel biosensors.

ANALYTICA CHIMICA ACTA (2022)

Article Chemistry, Multidisciplinary

Se-Containing MOF Coated Dual-Fe-Atom Nanozymes With Multi-Enzyme Cascade Activities Protect Against Cerebral Ischemic Reperfusion Injury

Ruizhen Tian et al.

Summary: In this study, a dual-atom nanozyme with multi-enzyme cascade antioxidant system was successfully constructed for protecting against brain tissue damage caused by ROS generation during cerebral ischemia-reperfusion. The designed nanozyme exhibited higher catalytic activities and improved stability and biocompatibility compared to single-atom nanozyme. Both in vitro and in vivo results demonstrated that the multifunctional antioxidant nanoparticles were effective in counteracting oxidative damage and inhibiting neural apoptosis.

ADVANCED FUNCTIONAL MATERIALS (2022)

Article Chemistry, Multidisciplinary

Guided Synthesis of a Mo/Zn Dual Single-Atom Nanozyme with Synergistic Effect and Peroxidase-like Activity

Chong-Bo Ma et al.

Summary: This study presents a facile synthetic strategy for a dual single-atom nanozyme composed of zinc (Zn) and molybdenum (Mo). The nanozyme utilizes polyoxometalates and supramolecular coordination complexes as metal-atom precursors, and an amphiphilic aerogel as the supporting substrate. The dual single-atoms of Zn and Mo exhibit a synergistic effect and peroxidase-like activity. The nanozyme shows outstanding stability and is capable of detecting various analytes in different samples.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

Article Biophysics

A biosensor based on the biomimetic oxidase Fe3O4@MnO2 for colorimetric determination of uric acid

Wei Yang et al.

Summary: A biosensor based on Fe3O4@MnO2 NS was constructed for colorimetric determination of uric acid in plasma. The method allows quantitative detection of UA through specific catalytic reactions, and colorimetric analysis can be performed through naked eye, smartphone, and UV-vis spectrophotometer.

COLLOIDS AND SURFACES B-BIOINTERFACES (2022)

Article Chemistry, Analytical

Surface-enhanced Raman spectroscopy biosensor based on silver nanoparticles@metal-organic frameworks with peroxidase-mimicking activities for ultrasensitive monitoring of blood cholesterol

Yan Wu et al.

Summary: In this study, a peroxidase-mimicking nanozyme was prepared by growing silver nanoparticles on the surface of a metal-organic framework. The nanozyme not only served as a surface-enhanced Raman spectroscopy substrate, but also effectively catalyzed the oxidation of leucomalachite green into malachite green. The nanozyme was successfully applied for the sensitive detection of cholesterol.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

Article Multidisciplinary Sciences

Single-atom nanozymes catalytically surpassing naturally occurring enzymes as sustained stitching for brain trauma

Shaofang Zhang et al.

Summary: The authors developed single-atom nanozymes of RhN4, VN4, and Fe-Cu-N-6 with higher catalytic activities than natural enzymes, and demonstrated the recyclability of Rh/VN4 and the scalp healing properties in bioactive sutures.

NATURE COMMUNICATIONS (2022)

Article Chemistry, Analytical

Histidine-engineered metal-organic frameworks with enhanced peroxidase-like activity for sensitive detection of metallothioneins

Meng Sha et al.

Summary: The design of defect-engineered MOFs with histidine-functionalized active sites, such as His-MIL-101, effectively mimics the catalytic pocket of natural enzymes and exhibits double the peroxidase-like activity of parent MOFs. This approach opens up possibilities for developing advanced biomimetic nanomaterials for biosensing applications.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

Article Engineering, Environmental

Iron single-atom anchored N-doped carbon as a 'laccase-like' nanozyme for the degradation and detection of phenolic pollutants and adrenaline

Yamei Lin et al.

Summary: A novel nitrogen-doped carbon material Fe1@CN20 was developed as a laccase mimic, offering better stability and recyclability, and showing more sensitive performance in the detection and degradation of phenolic compounds.

JOURNAL OF HAZARDOUS MATERIALS (2022)

Article Chemistry, Multidisciplinary

A Cerium Vanadate Nanozyme with Specific Superoxide Dismutase Activity Regulates Mitochondrial Function and ATP Synthesis in Neuronal Cells

Namrata Singh et al.

Summary: The study demonstrates that CeVO4 nanozyme can substitute the function of SOD1 and SOD2 in neuronal cells even when the natural enzymes are down-regulated. The nanozyme prevents mitochondrial damage by regulating superoxide levels and restores physiological levels of anti-apoptotic proteins. Additionally, it effectively prevents mitochondrial depolarization and improves cellular ATP levels under oxidative stress.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Review Chemistry, Physical

Carbon-based nanozymes for biomedical applications

Hui Ding et al.

Summary: Nanozymes are nanomaterials with enzyme-like properties that address the limitations of traditional enzymes and offer multifunctional platforms for biomedical applications. Carbon nanomaterials, with well-defined structures, have shown to be ideal substitutes for traditional enzymes in mimicking the catalytic centers of natural enzymes.

NANO RESEARCH (2021)

Article Nanoscience & Nanotechnology

A Functionalized Octahedral Palladium Nanozyme as a Radical Scavenger for Ameliorating Alzheimer's Disease

Zhi Jia et al.

Summary: The study demonstrates that the borneol-modified octahedral palladium nanozyme platform can efficiently reduce ROS and Ca2+ contents, protect mitochondria, and improve learning and memory functions in AD mice.

ACS APPLIED MATERIALS & INTERFACES (2021)

Review Chemistry, Inorganic & Nuclear

Nanozymes: Activity origin, catalytic mechanism, and biological application

Wenping Yang et al.

Summary: Nanozymes have significant advantages over natural enzymes and have been widely used in various fields due to their low cost, high stability, controllable activity, and reusability. This review comprehensively analyzes the source of nanozyme catalytic activities, discusses their catalytic mechanism and multiple enzyme-like activities, and reviews biological applications based on RONS regulation. The current challenges and future research directions of nanozymes are also presented.

COORDINATION CHEMISTRY REVIEWS (2021)

Article Engineering, Environmental

?Laccase-like? properties of coral-like silver citrate micro-structures for the degradation and determination of phenolic pollutants and adrenaline

Aneesh Koyappayil et al.

Summary: This study presents a simple functional laccase mimic based on coral-like silver citrate microstructures, showing excellent laccase-like activity in oxidizing phenolic substrates and the endocrine hormone adrenaline.

JOURNAL OF HAZARDOUS MATERIALS (2021)

Article Chemistry, Analytical

In Situ Exsolution of Noble-Metal Nanoparticles on Perovskites as Enhanced Peroxidase Mimics for Bioanalysis

Xiaoqian Jiang et al.

Summary: Various transition-metal oxide-based nanomaterials have been explored for peroxidase-like activity, with the enhancement of noble-metal nanozymes on the surface of TMOs to prevent aggregation. The exsolution of noble-metal NPs from perovskite oxides significantly enhances stability and peroxidase-like activity. The optimized Ir/LMIO composite shows high stability and excellent peroxidase-like activity for biosensing applications.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Single-Atom Pd Nanozyme for Ferroptosis-Boosted Mild-Temperature Photothermal Therapy

Mengyu Chang et al.

Summary: Photothermal therapy (PTT) is a promising tumor therapeutic modality, but minimizing damage to healthy tissues while maximizing efficiency is crucial. Utilizing a single-atom nanozyme (SAzyme) can improve the effectiveness of mild PTT by promoting ferroptosis.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Review Chemistry, Multidisciplinary

Advances in oxidase-mimicking nanozymes: Classification, activity regulation and biomedical applications

Yu Chong et al.

Summary: This article introduces the classification, catalytic mechanisms, and methods for regulating the activity of oxidase-mimicking nanozymes, discusses their potential applications in the biomedical field, and also points out the research opportunities and challenges in this area.

NANO TODAY (2021)

Article Chemistry, Physical

Matching the kinetics of natural enzymes with a single-atom iron nanozyme

Shufang Ji et al.

Summary: By precisely controlling the electronic structure of the single-atom iron active center, FeN3P-SAzyme exhibits catalytic activity and kinetics comparable to natural enzymes, showing promising potential as an effective therapeutic strategy for inhibiting tumor cell growth.

NATURE CATALYSIS (2021)

Review Chemistry, Multidisciplinary

Enzyme Mimics for Engineered Biomimetic Cascade Nanoreactors: Mechanism, Applications, and Prospects

Xianlong Zhang et al.

Summary: Multiple enzyme-driven biological catalytic cascades occur in living organisms, and efforts have been devoted to developing novel cascade catalytic systems mimicking these biological cascades. Nanozymes, as enzyme mimics, have significantly advanced the development of biomimetic cascade nanoreactors, leading to advancements in biosensing and biomedical applications. Progress in understanding and utilizing nanozyme-engineered biomimetic cascade catalytic nanoreactors for biosensing and biomedical applications is comprehensively covered in this article.

ADVANCED FUNCTIONAL MATERIALS (2021)

Article Chemistry, Multidisciplinary

A Tandem Strategy for Enhancing Electrochemical CO2 Reduction Activity of Single-Atom Cu-S1N3 Catalysts via Integration with Cu Nanoclusters

Datong Chen et al.

Summary: In this study, a tandem electrocatalyst for CO2-to-CO conversion was developed, achieving high Faradaic efficiency and stability. The asymmetric Cu-S1N3 atomic interface, along with the adjacent Cu-x, promotes proton-coupled electron transfer over atomic-level catalytic sites.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Modulating Coordination Environment of Single-Atom Catalysts and Their Proximity to Photosensitive Units for Boosting MOF Photocatalysis

Xing Ma et al.

Summary: A general and facile strategy for the construction of high-loading single-atom catalysts with a tunable coordination microenvironment has been developed based on metal-organic frameworks. The well-accessible and atomically dispersed metal sites possess close proximity to photosensitive units, greatly accelerating charge transfer and promoting photocatalysis. The optimized Ni-1-S/MOF with a unique Ni(I) microenvironment presents excellent photocatalytic H-2 production activity, surpassing other counterparts.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

Aptamer-Modified Cu2+-Functionalized C-Dots: Versatile Means to Improve Nanozyme Activities-Aptananozymes

Yu Ouyang et al.

Summary: The covalent linkage of aptamer binding sites to nanoparticle nanozymes improves catalytic activity by concentrating reaction substrates at the core, mimicking native enzymes. Aptamer-modified Cu2+ ion-functionalized C-dots show superior catalytic activity as aptananozymes, with enhanced functions controlled by the aptamer structure. Chiroselective catalysis and mechanistic studies are also discussed.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Analytical

A sensitive colorimetric sensor based on one-pot preparation of h-Fe3O4@ppy with high peroxidase-like activity for determination of glutathione and H2O2

Wei Yang et al.

Summary: Artificial mimic enzyme has become a powerful substitute for natural enzyme, with nano-enzymes biosensors being the focus of current research. A novel magnetic ternary nanocomposite, hemin-Fe3O4@polypyrrole, exhibited stronger peroxidase activity than Fe3O4 and h-ppy nanoparticles, making it a promising candidate for biosensor construction.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Review Chemistry, Multidisciplinary

Single-atom catalysis in advanced oxidation processes for environmental remediation

Yanan Shang et al.

Summary: Carbon-based single atom catalysts show high performances and efficiency in environmental catalysis, but there is a lack of comprehensive research on their catalytic sites and mechanisms in advanced oxidation processes, which is necessary for further exploration.

CHEMICAL SOCIETY REVIEWS (2021)

Review Chemistry, Physical

Metal single-atom catalysts for selective hydrogenation of unsaturated bonds

Zhiyi Sun et al.

Summary: Selective hydrogenation is widely used in various fields, and single atom catalysts show excellent catalytic performance by reducing the particle size to the single atom level. Research progress indicates that synthesis methods, composition content, monatomic coordination, and the charge relationship between metal and carrier all affect the catalytic performance of single atom catalysts.

JOURNAL OF MATERIALS CHEMISTRY A (2021)

Article Chemistry, Multidisciplinary

Styrene Hydroformylation with In Situ Hydrogen: Regioselectivity Control by Coupling with the Low-Temperature Water-Gas Shift Reaction

Tianbo Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Editorial Material Materials Science, Multidisciplinary

Recent progresses in the research of single-atom catalysts

Jun Li et al.

SCIENCE CHINA-MATERIALS (2020)

Article Nanoscience & Nanotechnology

Single-atom Rh/N-doped carbon electrocatalyst for formic acid oxidation

Yu Xiong et al.

NATURE NANOTECHNOLOGY (2020)

Article Chemistry, Multidisciplinary

Self-Assembled Pd12 Coordination Cage as Photoregulated Oxidase-Like Nanozyme

Soumalya Bhattacharyya et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Chemistry, Multidisciplinary

Atomic engineering of single-atom nanozymes for enzyme-like catalysis

Weiwei Wu et al.

CHEMICAL SCIENCE (2020)

Review Chemistry, Multidisciplinary

Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications

Yanyan Huang et al.

CHEMICAL REVIEWS (2019)

Review Chemistry, Multidisciplinary

Nanozyme: new horizons for responsive biomedical applications

Dawei Jiang et al.

CHEMICAL SOCIETY REVIEWS (2019)