4.6 Article

Highly Sensitive and Selective Graphene Nanoribbon Based Enzymatic Glucose Screen-Printed Electrochemical Sensor

Journal

SENSORS
Volume 22, Issue 24, Pages -

Publisher

MDPI
DOI: 10.3390/s22249590

Keywords

glucose oxidase; electrochemical biosensor; glucose; electrochemical analysis; graphene nanoribbons; screen-printed electrodes

Funding

  1. Slovenian Research Agency (ARRS)
  2. [P1-0153]
  3. [P1-0175]
  4. [P2-0423]

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A simple, sensitive, cost-effective, and reliable enzymatic glucose biosensor was developed and tested. The sensor showed good performance in detecting glucose in food and beverage samples, demonstrating its suitability for practical applications.
A simple, sensitive, cost effective, and reliable enzymatic glucose biosensor was developed and tested. Nitrogen-doped heat-treated graphene oxide nanoribbons (N-htGONR) were used for modification of commercially available screen-printed carbon electrodes (SPCEs), together with MnO2 and glucose oxidase. The resulting sensors were optimized and used to detect glucose in a wide linear range (0.05-5.0 mM) by a simple amperometric method, where the limit of detection was determined to be 0.008 mM. (lifetime), and reproducibility studies were also carried out and yielded favorable results. The sensor was then tested against potential interfering species present in food and beverage samples before its application to real matrix. Spiked beer samples were analyzed (with glucose recovery between 93.5 and 103.5%) to demonstrate the suitability of the developed sensor towards real food and beverage sample applications.

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