Plasmonic Biosensors with Nanostructure for Healthcare Monitoring and Diseases Diagnosis

Nanophotonics has been widely utilized in enhanced molecularspectroscopy or mediated chemical reaction, which has major applications in the field of enhancing sensing and enables opportunities in developing healthcare monitoring. This review presents an updated overview of the recent exciting advances of plasmonic biosensors in the healthcare area. Manufacturing, enhancements and applications of plasmonic biosensors are discussed, with particular focus on nanolisted main preparation methods of various nanostructures, such as chemical synthesis, lithography, nanosphere lithography, nanoimprint lithography, etc., and describing their respective advances and challenges from practical applications of plasmon biosensors. Based on these sensing structures, different types of plasmonic biosensors are summarized regarding detecting cancer biomarkers, body fluid, temperature, gas and COVID-19. Last, the existing challenges and prospects of plasmonic biosensors combined with machine learning, mega data analysis and prediction are surveyed.

Automated summary

This review provides an updated overview of the applications of nanophotonics in enhancing molecular spectroscopy and enabling chemical reactions, with a focus on plasmonic biosensors in the healthcare field. It discusses the manufacturing, enhancements, and applications of plasmonic biosensors, particularly the preparation methods of various nanostructures and their respective advances and challenges. Different types of plasmonic biosensors for detecting cancer biomarkers, body fluid, temperature, gas, and COVID-19 are summarized, and the challenges and prospects of combining plasmonic biosensors with machine learning and big data analysis are surveyed.