Open assessment of the therapeutic and rate-dependent effects of brain balance center? and interactive metronome? exercises on children with attention deficit hyperactivity disorder

The aim of this open study was to delineate domains of benefit and effect size measures to design an appro-priately powered randomized control trial to assess the efficacy of Brain Balance@ exercises and Interactive Metronome@ training (BB/IM) on ADHD symptoms in children. Participants underwent an extensive 15-week, 5 time per week, at-home training program. Results were assessed in 16 youths with ADHD (14M/2F, 10.8 +/- 1.7 years) who completed the program and compared to 8 typically developing controls (4M/F4, 11.0 +/- 1.8 years). BB/IM was associated with a significant reduction of 8.3 and 8.2 points on the Conner's Parent Rating Scale - Revised and the ADHD Rating Scale - IV. BB/IM was not associated with improvement on the Quotient ADHD System but with rate-dependent effects on hyperactivity and attention that were similar to previously reported effects of low dose methylphenidate. Both therapeutic and rate-dependent effects were observed on the Tower of London. The study provides information that could be used to design a randomized control trial, which is required for proof of efficacy. A key limitation is that 59% of the 39 enrolled participants with ADHD dropped out of the study and a new study should include multiple ratings during the course of treatment.

Automated summary

The aim of this study was to assess the efficacy of Brain Balance@ exercises and Interactive Metronome@ training on ADHD symptoms in children, and to provide information for the design of a randomized control trial. Results showed significant reduction of ADHD symptoms with these interventions, but limited improvement on ADHD rating system. More research is needed with higher participant retention rate and multiple ratings during treatment course.