4.6 Article

Integrative visualization of the molecular structure of a cellular microdomain

Journal

PROTEIN SCIENCE
Volume 32, Issue 3, Pages -

Publisher

WILEY
DOI: 10.1002/pro.4577

Keywords

Caulobacter crescentus; cellular condensate; integrative structural biology; intrinsically disordered protein; molecular visualization; PopZ

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This article uses an integrative approach to visualize the structural biology of the polar microdomain of Caulobacter crescentus, based on current molecular and cellular knowledge. The collaborative process of research and execution has identified both well-determined aspects and areas requiring further study. The visualization serves various purposes, such as dissemination, education, and outreach, and lays the foundation for future 3D modeling and simulation of cellular condensates.
An integrative approach to visualization is used to create a visual snapshot of the structural biology of the polar microdomain of Caulobacter crescentus. The visualization is based on the current state of molecular and cellular knowledge of the microdomain and its cellular context. The collaborative process of researching and executing the visualization has identified aspects that are well determined and areas that require further study. The visualization is useful for dissemination, education, and outreach, and the study lays the groundwork for future 3D modeling and simulation of this well-studied example of a cellular condensate.

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