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PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2008)
Long QT Syndrome and Short QT Syndrome
Wojciech Zareba et al.
PROGRESS IN CARDIOVASCULAR DISEASES (2008)
Dynamic interactions of an intracellular Ca2+ clock and membrane ton channel clock underlie robust initiation and regulation of cardiac pacemaker function
Victor A. Maltsev et al.
CARDIOVASCULAR RESEARCH (2008)
A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance
Earl Gordon et al.
CARDIOVASCULAR RESEARCH (2008)
KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval
Alicia Lundby et al.
HEART RHYTHM (2007)
HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice
Stefan Herrmann et al.
EMBO JOURNAL (2007)
Expression of SERCA isoform with faster Ca2+ transport properties improves postischemic cardiac function and Ca2+ handling and decreases myocardial infarction
M. A. Hassan Talukder et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Discovery of the sinus node by Keith and Flack: on the centennial of their 1907 publication
Mark E. Silverman et al.
HEART (2007)
Age-related down-regulation of HCN channels in rat sinoatrial node
Xin Huang et al.
BASIC RESEARCH IN CARDIOLOGY (2007)
被撤回的出版物: Novel approaches for gene-specific interference manipulating actions of via microRNAS:: Examination on the pacemaker channel genes HCN2 and HCN4 (Retracted article. See vol. 227, pg. 877, 2012)
Jiening Xiao et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
被撤回的出版物: Transcriptional activation by stimulating protein 1 and post-transcriptional repression by muscle-specific microRNAs of IKS-encodina genes and potential implications in regional heterogeneity of their expressions (Retracted article. See vol. 227, pg. 877, 2012)
Xiaobin Luo et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardia
Eyal Nof et al.
CIRCULATION (2007)
Pathophysiology of HCN channels
Stefan Herrmann et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
Regulation of cardiac ion channels via non-genomic action of sex steroid hormones: Implication for the gender difference in cardiac arrhythmias
Tetsushi Furukawa et al.
PHARMACOLOGY & THERAPEUTICS (2007)
Store-operated Ca2+ influx and expression of TRPC genes in mouse sinoatrial node
Yue-Kun Ju et al.
CIRCULATION RESEARCH (2007)
A mechanism for sudden infant death syndrome (SIDS): Stress-induced leak via ryanodine receptors
David J. Tester et al.
HEART RHYTHM (2007)
MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts
Jiening Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Organisation of the mouse sinoatrial node: structure and expression of HCN channels
Jie Liu et al.
CARDIOVASCULAR RESEARCH (2007)
Slow delayed rectifier potassium current (I-Ks) and the repolarization reserve
Norbert Jost et al.
ANNALS OF NONINVASIVE ELECTROCARDIOLOGY (2007)
Drug-induced long QT and torsade de pointes: recent advances
Prince J. Kannankeril et al.
CURRENT OPINION IN CARDIOLOGY (2007)
The funny current - Cellular basis for the control of heart rate
Dario DiFrancesco et al.
DRUGS (2007)
Differential expression of ion channel transcripts in atrial muscle and sinoatrial node in rabbit
James O. Tellez et al.
CIRCULATION RESEARCH (2006)
Extended atrial conduction system characterised by the expression of the HCN4 channel and connexin45
Mitsuru Yamamoto et al.
CARDIOVASCULAR RESEARCH (2006)
New perspectives on the role of SERCA2's Ca2+ affinity in cardiac function
P. Vangheluwe et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2006)
Membrane potential fluctuations resulting from submembrane Ca2+ releases in rabbit sinoatrial nodal cells impart an exponential phase to the late diastolic depolarization that controls their chronotropic state
Konstantin Y. Bogdanov et al.
CIRCULATION RESEARCH (2006)
A pattern-based method for the identification of microRNA binding sites and their corresponding heteroduplexes
Kevin C. Miranda et al.
CELL (2006)
Molecular determinants of altered Ca2+ handling in human chronic atrial fibrillation
Ali El-Armouche et al.
CIRCULATION (2006)
Bradycardia and slowing of the atrioventricular conduction in mice lacking CaV3.1/α1G T-type calcium channels
ME Mangoni et al.
CIRCULATION RESEARCH (2006)
Brief report - Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel
R Milanesi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
The cardiac hERG/I-Kr potassium channel as pharmacological target: Structure, function, regulation, and clinical applications
D. Thomas et al.
CURRENT PHARMACEUTICAL DESIGN (2006)
miRBase: microRNA sequences, targets and gene nomenclature
Sam Griffiths-Jones et al.
NUCLEIC ACIDS RESEARCH (2006)
Expression and transcriptional control of human KCNE genes
AL Lundquist et al.
GENOMICS (2006)
The KCNQ1 potassium channel: From gene to physiological function
T Jespersen et al.
PHYSIOLOGY (2005)
Pathophysiological significance of T-type Ca2+ channels:: Properties and functional roles of T-type Ca2+ channels in cardiac pacemaking
K Ono et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2005)
Functional roles of Cav1.3(α1D) calcium channels in atria insights gained from gene-targeted null mutant mice
Z Zhang et al.
CIRCULATION (2005)
The N588K-HERG K+ channel mutation in the 'short QT syndrome':: Mechanism of gain-in-function determined at 37 °C
MJ McPate et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Intracellular calcium release and cardiac disease
XHT Wehrens et al.
ANNUAL REVIEW OF PHYSIOLOGY (2005)
Modulating sarco(endo)plasmic reticulum Ca2+ ATPase 2 (SERCA2) activity: Cell biological implications
P Vangheluwe et al.
CELL CALCIUM (2005)
A rapidly activating delayed rectifier K+ current regulates pacemaker activity in adult mouse sinoatrial node cells
RB Clark et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Impairment of HERG K+ channel function by tumor necrosis factor-α -: Role of reactive oxygen species as a mediator
JX Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Pharmacology of cardiac potassium channels
J Tamargo et al.
CARDIOVASCULAR RESEARCH (2004)
Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity
JEJ Schultz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Low incidence of cardiac events with β-blocking therapy in children with long QT syndrome
E Villain et al.
EUROPEAN HEART JOURNAL (2004)
Novel therapeutic approaches for heart failure by normalizing calcium cycling
XHT Wehrens et al.
NATURE REVIEWS DRUG DISCOVERY (2004)
Biology of cardiac arrhythmias - Ion channel protein trafficking
BP Delisle et al.
CIRCULATION RESEARCH (2004)
Disturbed atrio-ventricular conduction and normal contractile function in isolated hearts from Cav1.3-knockout mice
J Matthes et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2004)
Functions of erg K+ channels in excitable cells
JR Schwarz et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2004)
The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart
J Stieber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Abnormal coronary function in mice deficient in α1H T-type Ca2+ channels
CC Chen et al.
SCIENCE (2003)
Myocardial infarction causes increased expression but decreased activity of the myocardial Na+-Ca2+ exchanger in the rabbit
FR Quinn et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Structural basis for modulation and agonist specificity of HCN pacemaker channels
WN Zagotta et al.
NATURE (2003)
Phospholamban: A crucial regulator of cardiac contractility
DH MacLennan et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death
XHT Wehrens et al.
CELL (2003)
Calcium and potassium currents in cells from adult and aged canine right atria
W Dun et al.
CARDIOVASCULAR RESEARCH (2003)
Pacemaker channel dysfunction in a patient with sinus node disease
E Schulze-Bahr et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Partial rescue of the Na+-Ca2+ exchanger (NCX1) knock-out mouse by transgenic expression of NCX1
CH Cho et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2003)
Functional role of L-type Cav13Ca2+ channels in cardiac pacemaker activity
ME Mangoni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2
A Ludwig et al.
EMBO JOURNAL (2003)
Sarcoplasmic reticulum Ca2+-ATPase modulates cardiac contraction and relaxation
KF Frank et al.
CARDIOVASCULAR RESEARCH (2003)
Luminal Ca2+ controls termination and refractory behavior of Ca2+-induced Ca2+ release in cardiac myocytes
D Terentyev et al.
CIRCULATION RESEARCH (2002)
Atria-sinus interaction demonstrated by blockade of the rapid delayed rectifier current
EE Verheijck et al.
CIRCULATION (2002)
Altered Na/Ca exchange activity in cardiac hypertrophy and heart failure: a new target for therapy?
KR Sipido et al.
CARDIOVASCULAR RESEARCH (2002)
The contribution of ionic currents to changes in refractoriness of human atrial myocytes associated with chronic atrial fibrillation
AJ Workman et al.
CARDIOVASCULAR RESEARCH (2001)
Sinoatrial nodal cell ryanodine receptor and Na+-Ca2+ exchanger -: Molecular partners in pacemaker regulation
KY Bogdanov et al.
CIRCULATION RESEARCH (2001)
Molecular mechanism of cAMP modulation of HCN pacemaker channels
BJ Wainger et al.
NATURE (2001)
Calmodulin binding and inhibition of cardiac muscle calcium release channel (ryanodine receptor)
DM Balshaw et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Autoantibodies from mothers of children with congenital heart block downregulate cardiac L-type ca channels
YX Qu et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Na+-Ca2+ exchanger remodeling in pressure overload cardiac hypertrophy
ZY Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Cardiac Na+-Ca2+ exchange -: Molecular and pharmacological aspects
M Shigekawa et al.
CIRCULATION RESEARCH (2001)
Sudden cardiac death:: role of heart rate variability to identify patients at risk
F Lombardi et al.
CARDIOVASCULAR RESEARCH (2001)
Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization
SV Koushik et al.
FASEB JOURNAL (2001)
Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia
PJ Laitinen et al.
CIRCULATION (2001)
Effects of sex and age on electrocardiographic and cardiac electrophysiological properties in adults
T Taneja et al.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY (2001)
Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2+ channels
J Platzer et al.
CELL (2000)