4.6 Article

The relationship of rheological properties and the performance of silk fibroin hydrogels in tissue engineering application

Related references

Note: Only part of the references are listed.
Article Chemistry, Physical

Alginate Hydrogels with Aloe vera: The Effects of Reaction Temperature on Morphology and Thermal Properties

Katarzyna Bialik-Was et al.

Summary: In this study, the impact of reaction temperature on the physical and chemical properties of sodium alginate/poly (vinyl alcohol)-based hydrogels was investigated. It was found that higher temperatures promoted the crosslinking reaction, and the addition of Aloe vera as a bioadditive further enhanced the reaction.

MATERIALS (2022)

Review Engineering, Biomedical

Natural Biomaterials from Biodiversity for Healthcare Applications

Erick Insuasti-Cruz et al.

Summary: Natural biomaterials sourced from various organisms have diverse properties and applications in healthcare. While they show promise, there are limitations to be addressed. Future research should focus on discovering and studying more natural biomaterials to expand their potential uses.

ADVANCED HEALTHCARE MATERIALS (2022)

Article Pharmacology & Pharmacy

Silk fibroin hydrogel containing Sesbania sesban L. extract for rheumatoid arthritis treatment

Duy Toan Pham et al.

Summary: This study developed a novel silk fibroin in-situ hydrogel containing Sesbania sesban L. extract, which has high anti-inflammatory actions and shows potential for rheumatoid arthritis treatments.

DRUG DELIVERY (2022)

Article Biochemistry & Molecular Biology

β-Sheet to Random Coil Transition in Self-Assembling Peptide Scaffolds Promotes Proteolytic Degradation

Elsa Genove et al.

Summary: This study investigates the protease sensitivity of the self-assembling peptide RAD16-I, and demonstrates that it can be enzymatically degraded into short peptide sequences and further degraded into single amino acids, making it suitable for applications in tissue engineering and regenerative medicine.

BIOMOLECULES (2022)

Article Chemistry, Applied

Thiolated hyaluronic acid/silk fibroin dual-network hydrogel incorporated with bioglass nanoparticles for wound healing

Yifeng Yu et al.

Summary: THA conjugates combined with SF and bioactive glass nanoparticles were used to build a novel type of composite hydrogel with a dual-network structure. The hydrogel showed enhanced strength and stiffness compared to individual components and exhibited sustained release of Si ions. In vitro and in vivo experiments demonstrated its potential for use in cell culture and wound healing.

CARBOHYDRATE POLYMERS (2022)

Review Polymer Science

Mimicry of silk utilizing synthetic polypeptides

Nicholas J. Chan et al.

Summary: Silk and silk-based materials have been used by mankind for thousands of years and are now finding increasing applications in biomedical and advanced technologies. Chemical polymerization methods have been developed to overcome the limitations of natural silks and create synthetic materials with silk-like features. This article summarizes the physicochemical properties of silks and explores how the structure-property relationships of silks have inspired material design, with a focus on polypeptide synthesis using N-carboxyanhydride ring-opening polymerization (NCA ROP). The prospects of silk-inspired material design, including the use of amorphous polymers with ss-sheet structures for high-performance polymers, are also discussed.

PROGRESS IN POLYMER SCIENCE (2022)

Review Multidisciplinary Sciences

Hydrogel based tissue engineering and its future applications in personalized disease modeling and regenerative therapy

Shikha Chaudhary et al.

Summary: This review paper focuses on the novel approach of organoid culture, discussing its advantages and limitations, as well as potential applications in various areas of life sciences including cancer research, cell therapy, tissue engineering, personalized medicine, and drug discovery.

BENI-SUEF UNIVERSITY JOURNAL OF BASIC AND APPLIED SCIENCES (2022)

Review Engineering, Biomedical

Crosslinking strategies for silk fibroin hydrogels: promising biomedical materials

Maryam Farokhi et al.

Summary: Silk fibroin hydrogels have strong biomimetic potential and are excellent candidates for tissue engineering due to their tunable properties. Different crosslinking strategies, either chemical or physical, can alter the structure of silk fibroin and improve its mechanical stability. However, each method has its own advantages and disadvantages, and the choice of method depends on the specific application requirements.

BIOMEDICAL MATERIALS (2021)

Article Biochemistry & Molecular Biology

Hydrogel-Based Bioinks for Cell Electrowriting of Well-Organized Living Structures with Micrometer-Scale Resolution

Miguel Castilho et al.

Summary: Novel hydrogel-based bioinks for cell electrowriting (CEW) have been developed to fabricate well-organized cell-laden fiber structures with diameters ranging from 5 to 40 μm, opening up exciting opportunities for the manufacture of microstructured constructs in regenerative medicine and in vitro models.

BIOMACROMOLECULES (2021)

Review Biochemistry & Molecular Biology

Engineering of sustainable biomaterial composites from cellulose and silk fibroin: Fundamentals and applications

Marc Kostag et al.

Summary: This review explores composites prepared from cellulose and silk fibroin for tissue engineering applications. The discussion on molecular structures, dissolution mechanisms, and fabrication and characterization of these materials reveals that they exhibit improved mechanical properties compared to precursor biopolymers, making them excellent candidates for biomedical applications due to their inherent biocompatibility.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Chemistry, Multidisciplinary

Efficient Regulation of the Behaviors of Silk Fibroin Hydrogel via Enzyme-Catalyzed Coupling of Hyaluronic Acid

Lin Wang et al.

Summary: The study demonstrates the enhancement of structural stability and flexibility of silk fibroin (SF) hydrogel through the synthesis of a composite double-network hydrogel. The swelling ratio, mechanical property, drug loading, and release behaviors of the hydrogel can be controlled by various methods, offering potential for applications in drug delivery systems.

LANGMUIR (2021)

Review Chemistry, Analytical

Electrophysiology Read-Out Tools for Brain-on-Chip Biotechnology

Csaba Forro et al.

Summary: Brain-on-Chip (BoC) biotechnology combines lab-on-chip and cell biology to replicate brain structures more faithfully in vitro, with a focus on studying brain activity in health and disease through electrophysiology techniques. However, the availability of BoC-electrophysiology platforms is currently limited as the technology is still in its early stages.

MICROMACHINES (2021)

Review Engineering, Biomedical

Processing, mechanical properties and bio-applications of silk fibroin-based high-strength hydrogels

Yu Zhao et al.

Summary: Hydrogels are versatile materials in biomedical engineering with applications similar to wet tissues. Silk fibroin (SF) is a natural polymer with biocompatibility and tunable biodegradation, but its poor mechanical performance hinders its structural applications. Researchers are exploring strategies to enhance the strength of SF-based hydrogels for biomedical uses.

ACTA BIOMATERIALIA (2021)

Article Chemistry, Applied

Natural silk nanofibrils as reinforcements for the preparation of chitosan-based bionanocomposites

Liang Li et al.

Summary: Nanofibrils derived from natural biopolymers, such as silk, have been used to fabricate biocompatible chitosan nanocomposites with improved mechanical properties. The silk nanofibrils can be uniformly dispersed in chitosan solution to form multi-dimensional nanocomposites with enhanced mechanical strength and thermal stability. These bionanocomposites offer new opportunities for biomaterial applications due to their biocompatibility, biodegradability, and controllable mesoscopic structure.

CARBOHYDRATE POLYMERS (2021)

Article Chemistry, Applied

Self-healing and acidochromic polyvinyl alcohol hydrogel reinforced by regenerated cellulose

Lei Ding et al.

Summary: The study integrated acidochromic regenerated cellulose into polyvinyl alcohol/borax matrix to prepare a smart hydrogel with self-healing, color-tunable, and sol-gel conversion properties. The mechanical properties of the hydrogel were significantly improved after incorporating ARC, showing excellent self-healing and color tuning abilities.

CARBOHYDRATE POLYMERS (2021)

Article Biochemical Research Methods

3D bioprinted silk fibroin hydrogels for tissue engineering

Soon Hee Kim et al.

Summary: The development of biocompatible and precisely printable bioink addresses the growing demand for three-dimensional bioprinting applications in tissue engineering. The versatile bioink, with high mechanical stability and biocompatibility, can be broadly used in nerve tissue engineering and wound healing, among other applications.

NATURE PROTOCOLS (2021)

Review Biochemistry & Molecular Biology

Silk Fibroin as a Functional Biomaterial for Tissue Engineering

Weizhen Sun et al.

Summary: Tissue engineering involves combining cells, scaffold materials, and growth factors to regenerate or replace damaged tissues or organs. Silk fibroin has attracted attention for its outstanding properties and ability to be reconstructed into various material formats for tissue engineering applications.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Engineering, Biomedical

Tissue-engineered nerve graft using silk-fibroin/polycaprolactone fibrous mats decorated with bioactive cerium oxide nanoparticles

Jamileh Saremi et al.

Summary: This study evaluated the efficacy of cerium oxide nanoparticles (CNPs) encapsulated in hybrid silk-fibroin (SF)/polycaprolactone (PCL) nanofibers as an artificial neural guidance conduit (NGC) for peripheral nerve regeneration. Results showed that 1% CNPs concentration in the SF and SF/PCL conduits was optimal, and the controlled release of CNPs from the fibers was slow over 60 days. The double-layered NGC using CNPs + SF and CNPs + SF/PCL fibers showed promise for nervous tissue engineering and regenerative medicine in terms of structure and biocompatibility.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2021)

Article Chemistry, Physical

Pluronic F-127/Silk Fibroin for Enhanced Mechanical Property and Sustained Release Drug for Tissue Engineering Biomaterial

Jina Youn et al.

Summary: An injectable thermosensitive hydrogel was developed for drug and cellular delivery, combining pluronic F-127 and silk fibroin. The addition of silk fibroin to pluronic F-127 improved mechanical strength, decreased degradation rate, and enhanced the release of hydrophobic drugs. The composite showed promising potential as a cell and drug delivery system for tissue engineering and regenerative medicine.

MATERIALS (2021)

Article Polymer Science

Impacts of Blended Bombyx mori Silk Fibroin and Recombinant Spider Silk Fibroin Hydrogels on Cell Growth

Chavee Laomeephol et al.

Summary: Binary-blended hydrogels fabricated from Bombyx mori silk fibroin and recombinant spider silk protein showed improved gelation time and cellular interactions compared to individual materials, suggesting potential for biomedical applications. Mixing the two materials enhanced cellular activities, making the hydrogels suitable for various biomedical uses.

POLYMERS (2021)

Article Chemistry, Applied

Chitosan hydrogels in 3D printing for biomedical applications

Mina Rajabi et al.

Summary: Tissue engineering and regenerative medicine have progressed to a new stage due to recent advancements in biology, material sciences, and 3D printing. Chitosan-based hydrogels, widely used in biomedical applications, hold promise for future development when combined with 3D printing technology. This combination has the potential to create next generation biomedical implants.

CARBOHYDRATE POLYMERS (2021)

Article Polymer Science

Conjugation of CMCS to silk fibroin for tuning mechanical and swelling behaviors of fibroin hydrogels

Xuejie Yu et al.

Summary: A composite hydrogel of SF and CMCS was prepared to address the poor formability of pure SF hydrogels, showing improved mechanical properties and drug release behavior. Increasing CMCS content enhanced water retention ability and sustained release rate of the hydrogel. Introduction of CMCS also promoted cell proliferation, demonstrating excellent biocompatibility of the hydrogel.

EUROPEAN POLYMER JOURNAL (2021)

Article Chemistry, Medicinal

Chitosomes-In-Chitosan Hydrogel for Acute Skin Injuries: Prevention and Infection Control

Lisa Myrseth Hemmingsen et al.

Summary: In an era of antimicrobial resistance, novel treatment options are urgently needed to improve the prevention and eradication of infectious skin biofilm-producing pathogens, while enhancing wound healing. Tailoring formulations for acute skin injuries is crucial for proper skin retention and release of antimicrobials.

MARINE DRUGS (2021)

Article Engineering, Biomedical

Highly Stretchable, Adhesive, and Self-Healing Silk Fibroin-Dopted Hydrogels for Wearable Sensors

Li Zhao et al.

Summary: The one-pot method of thermal polymerization is introduced to fabricate silk fibroin-doped hydrogels, which exhibit excellent mechanical properties, adhesion, and self-healing capabilities, making them suitable for applications in pressure sensors and electronic skin fields.

ADVANCED HEALTHCARE MATERIALS (2021)

Review Polymer Science

Current Insight of Printability Quality Improvement Strategies in Natural-Based Bioinks for Skin Regeneration and Wound Healing

Syafira Masri et al.

Summary: The article introduces the application of skin tissue engineering and the latest research progress using 3D bioprinting technology to manufacture scaffolds, and discusses the limitations of current bioinks as well as the impact of the optimal printing technology application temperature.

POLYMERS (2021)

Review Pharmacology & Pharmacy

Silk Fibroin: An Ancient Material for Repairing the Injured Nervous System

Mahdi Yonesi et al.

Summary: Silk, a natural fiber spun by invertebrates, particularly the silk spun by silkworms, has excellent properties for tissue repair and medical applications. In the field of neural soft tissue engineering, silk has been widely used to promote neuronal growth and treat nervous system diseases such as stroke and Alzheimer's.

PHARMACEUTICS (2021)

Article Chemistry, Applied

Direct ink writing of aloe vera/cellulose nanofibrils bio-hydrogels

Hossein Baniasadi et al.

Summary: The cellulose nanofibrils reinforced aloe vera bio-hydrogels developed through DIW technique exhibited excellent viscoelastic properties and wet stability, making them promising for biomedical applications.

CARBOHYDRATE POLYMERS (2021)

Article Construction & Building Technology

The improvement of freezing-thawing resistance of concrete by cellulose/polyvinyl alcohol hydrogel

Kai Wu et al.

Summary: The research successfully improved the freeze-thaw resistance of concrete by fixing free water with cellulose/PVA hydrogel. The network structure of the hydrogel can prevent crack propagation caused by freeze-thaw attack and improve the pore structure of concrete.

CONSTRUCTION AND BUILDING MATERIALS (2021)

Article Biochemistry & Molecular Biology

Comparative Study of Silk Fibroin-Based Hydrogels and Their Potential as Material for 3-Dimensional (3D) Printing

Watcharapong Pudkon et al.

Summary: The study found that 2%wt SF-based hydrogels are suitable for 3D printing, demonstrating properties such as storage modulus, shear-thinning behavior, and degree of structure recovery.

MOLECULES (2021)

Review Chemistry, Physical

Advances in 3D Printing for Tissue Engineering

Angelika Zaszczynska et al.

Summary: This study summarizes the latest advancements in 3D printing techniques in tissue engineering applications, focusing on the systematics of available 3D printing techniques, printable biomaterials, and advancements in 3D printing-assisted tissue engineering.

MATERIALS (2021)

Article Entomology

CRISPR-Mediated Endogenous Activation of Fibroin Heavy Chain Gene Triggers Cellular Stress Responses in Bombyx mori Embryonic Cells

Wenbo Hu et al.

Summary: Through a CRISPRa approach, the activation of endogenous FibH gene expression in Bombyx mori embryonic cells led to an up-regulation of cellular stress response-related genes, indicating a positive correlation between activated FibH gene expression and cellular stress responses. This study provides insights into the development of silk gland cells and the fibroin secretion process in silkworms.

INSECTS (2021)

Article Polymer Science

Relationship between Structure and Rheology of Hydrogels for Various Applications

Gorjan Stojkov et al.

Summary: This review focuses on the correlation between the rheological characteristics of hydrogels and their potential applications. Various rheological tests are described and the results are reported, with a discussion on the most prevalent applications of hydrogels.
Article Engineering, Biomedical

Three-dimensional printed polylactic acid scaffold integrated with BMP-2 laden hydrogel for precise bone regeneration

Misun Cha et al.

Summary: This study investigated the effect of 3D printed PLA cage/Biogel scaffold system as a carrier of BMP-2 in rat calvaria defect and ectopic ossification models. The results demonstrated that this scaffold system effectively promoted bone regeneration and controlled bone formation in designed shapes.

BIOMATERIALS RESEARCH (2021)

Article Chemistry, Multidisciplinary

Investigation of the biological activity, mechanical properties and wound healing application of a novel scaffold based on lignin-agarose hydrogel and silk fibroin embedded zinc chromite nanoparticles

Reza Eivazzadeh-Keihan et al.

Summary: An innovative biocompatible nanobiocomposite scaffold was designed and prepared in this study, showing potential applications in wound healing based on various biological and structural tests. The addition of silk fibroin and ZnCr2O4 nanoparticles enhanced the mechanical properties of the material, demonstrating good hemocompatibility and antibacterial activity.

RSC ADVANCES (2021)

Review Materials Science, Biomaterials

Tissue adhesive hydrogel bioelectronics

Shengnan Li et al.

Summary: Flexible bioelectronics, particularly conductive and tissue adhesive hydrogels, have great potential in implantable wearable devices due to their unique mechanical properties and excellent biocompatibility. This review focuses on recent progress in tissue adhesive hydrogel bioelectronics, providing insights into the mechanism, preparation, fabrication strategies, and applications of these materials. Perspectives on the future development of tissue adhesive hydrogel bioelectronics are also discussed.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Review Nanoscience & Nanotechnology

Hybrid Gelatin Hydrogels in Nanomedicine Applications

Bidita Salahuddin et al.

Summary: Gelatin-based hydrogels combined with supporting materials are widely used in nanomedicine, exhibiting unique properties and various applications. Research on the fabrication methods and applications of hydrogels, as well as the characterization of related materials and application challenges, has been conducted.

ACS APPLIED BIO MATERIALS (2021)

Review Materials Science, Biomaterials

Functional silk fibroin hydrogels: preparation, properties and applications

Haiyan Zheng et al.

Summary: Traditional silk protein hydrogels have limitations in terms of structure and functionality, but the development of functional silk protein hydrogels presents opportunities to overcome these limitations, attracting attention from scholars worldwide.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Review Pharmacology & Pharmacy

Silk fibroin for skin injury repair: Where do things stand?

Mazaher Gholipourmalekabadi et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

Article Biochemistry & Molecular Biology

MMP-9 responsive dipeptide-tempted natural protein hydrogel-based wound dressings for accelerated healing action of infected diabetic wound

Jegatheeswaran Sonamuthu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Cell & Tissue Engineering

Injectable Silk-Based Hydrogel as an Alternative to Cervical Cerclage: A Rabbit Study

Yali Zhang et al.

TISSUE ENGINEERING PART A (2020)

Review Chemistry, Applied

Alginate hydrogels for bone tissue engineering, from injectables to bioprinting: A review

Aurora C. Hernandez-Gonzalez et al.

CARBOHYDRATE POLYMERS (2020)

Article Polymer Science

High-strength functionalized pectin/fibroin hydrogel with tunable properties: A structure-property relationship study

Sajedeh Khorshidi et al.

JOURNAL OF APPLIED POLYMER SCIENCE (2020)

Review Biochemistry & Molecular Biology

Spider Silk for Tissue Engineering Applications

Sahar Salehi et al.

MOLECULES (2020)

Article Chemistry, Multidisciplinary

Tunable Biomimetic Hydrogels from Silk Fibroin and Nanocellulose

Pramod Dorishetty et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2020)

Article Chemistry, Multidisciplinary

Printability of 3D Printed Hydrogel Scaffolds: Influence of Hydrogel Composition and Printing Parameters

Saman Naghieh et al.

APPLIED SCIENCES-BASEL (2020)

Article Materials Science, Multidisciplinary

Structure and properties of PVA/silk fibroin hydrogels and their effects on growth behavior of various cell types

Ruixia Hou et al.

MATERIALS RESEARCH EXPRESS (2020)

Article Chemistry, Multidisciplinary

A Chemically Defined Hydrogel for Human Liver Organoid Culture

Shicheng Ye et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Article Nanoscience & Nanotechnology

Alginate Hydrogels with Embedded ZnO Nanoparticles for Wound Healing Therapy

Carol M. Cleetus et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

Article Biochemistry & Molecular Biology

Stretchable silk fibroin hydrogels

C. B. Oral et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Review Chemistry, Multidisciplinary

Chitosan hydrogels for sustained drug delivery

S. Peers et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Review Polymer Science

Structural design toward functional materials by electrospinning: A review

Xiuling Yang et al.

E-POLYMERS (2020)

Review Materials Science, Biomaterials

Chemical and physical chitosan hydrogels as prospective carriers for drug delivery: a review

Bingren Tian et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Article Medicine, Research & Experimental

Bioinspired biliverdin/silk fibroin hydrogel for antiglioma photothermal therapy and wound healing

Qing Yao et al.

THERANOSTICS (2020)

Review Biochemistry & Molecular Biology

Alginate hydrogel dressings for advanced wound management

Miao Zhang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Review Chemistry, Physical

A review on recent advances in polymer and peptide hydrogels

Sanjoy Mondal et al.

SOFT MATTER (2020)

Article Biochemistry & Molecular Biology

High-strength and self-recoverable silk fibroin cryogels with anisotropic swelling and mechanical properties

Berkant Yetiskin et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Chemistry, Physical

Ultrastiff and Tough Supramolecular Hydrogels with a Dense and Robust Hydrogen Bond Network

Yan Jie Wang et al.

CHEMISTRY OF MATERIALS (2019)

Article Engineering, Biomedical

Potential use of silkworm gut fiber braids as scaffolds for tendon and ligament tissue engineering

Ana Pagan et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2019)

Review Mechanics

Dynamics, rheology, and applications of elastic deformable particle suspensions: a review

Massimiliano M. Villone et al.

RHEOLOGICA ACTA (2019)

Article Engineering, Environmental

Hydrogels with superior mechanical properties from the synergistic effect in hydrophobic-hydrophilic copolymers

Md. Tariful Islam Mredha et al.

CHEMICAL ENGINEERING JOURNAL (2019)

Article Nanoscience & Nanotechnology

Polyvinyl Alcohol/Silk Fibroin/Borax Hydrogel lonotronics: A Highly Stretchable, Self-Healable, and Biocompatible Sensing Platform

Ningning Yang et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Article Engineering, Environmental

A physically crosslinked, self-healing hydrogel electrolyte for nano-wire PANI flexible supercapacitors

Yingxi Lin et al.

CHEMICAL ENGINEERING JOURNAL (2019)

Article Nanoscience & Nanotechnology

Dexamethasone-loaded injectable silk-polyethylene glycol hydrogel alleviates cisplatin-induced ototoxicity

Yuming Chen et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Article Multidisciplinary Sciences

Effect of different cocoon stifling methods on the properties of silk fibroin biomaterials

Salvador D. Aznar-Cervantes et al.

SCIENTIFIC REPORTS (2019)

Article Materials Science, Textiles

Performance of Water-immiscible Silk Fibroin Based Hydrogel as Underwater Biomedical Adhesive

Meihua Yuan et al.

FIBERS AND POLYMERS (2019)

Article Biochemistry & Molecular Biology

Enhanced properties of injectable chitosan-based thermogelling hydrogels by silk fibroin and longan seed extract for bone tissue engineering

Porntipa Pankongadisak et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Materials Science, Biomaterials

Injectable Silk-Vaterite Composite Hydrogels with Tunable Sustained Drug Release Capacity

Caihong Zhu et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2019)

Article Chemistry, Applied

Poly(lactic acid) based hydrogels: formation, characteristics and biomedical applications

Somayyah Abdul Munim et al.

JOURNAL OF POROUS MATERIALS (2019)

Article Materials Science, Biomaterials

Conductive regenerated silk-fibroin-based hydrogels with integrated high mechanical performances

Feng Chen et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

Review Polymer Science

Rheological Study of Soft Matters: A Review of Microrheology and Microrheometers

Wei Liu et al.

MACROMOLECULAR CHEMISTRY AND PHYSICS (2018)

Review Engineering, Biomedical

Structured Macroporous Hydrogels: Progress, Challenges, and Opportunities

Kevin J. De France et al.

ADVANCED HEALTHCARE MATERIALS (2018)

Article Chemistry, Multidisciplinary

High-Strength, Durable All-Silk Fibroin Hydrogels with Versatile Processability toward Multifunctional Applications

Zhenghua Zhu et al.

ADVANCED FUNCTIONAL MATERIALS (2018)

Review Chemistry, Multidisciplinary

Biomedical Applications of Recombinant Silk-Based Materials

Tamara Bernadette Aigner et al.

ADVANCED MATERIALS (2018)

Article Biochemistry & Molecular Biology

Structure and interaction of silk fibroin and graphene oxide in concentrated solution under shear

Chao Zhang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Biochemistry & Molecular Biology

Antioxidant activity and controlled drug delivery potential of tragacanth gum-cl-poly (lactic acid-co-itaconic acid) hydrogel

Vinod Kumar Gupta et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Biochemistry & Molecular Biology

Thai silk fibroin gelation process enhancing by monohydric and polyhydric alcohols

Kanyaluk Kaewprasit et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Chemistry, Physical

Minimum Energy Paths and Transition States by Curve Optimization

Alain C. Vaucher et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2018)

Article Chemistry, Multidisciplinary

Effect of solution viscosity on retardation of cell sedimentation in DLP 3D printing of gelatin methacrylate/silk fibroin bioink

Kyunga Na et al.

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY (2018)

Article Engineering, Biomedical

Mechanical behaviour of alginate-gelatin hydrogels for 3D bioprinting

Michael Di Giuseppe et al.

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS (2018)

Review Engineering, Biomedical

Silk-Based Bioinks for 3D Bioprinting

Shikha Chawla et al.

ADVANCED HEALTHCARE MATERIALS (2018)

Article Nanoscience & Nanotechnology

Novel silk fibroin nanoparticles incorporated silk fibroin hydrogel for inhibition of cancer stem cells and tumor growth

Puyuan Wu et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)

Review Chemistry, Multidisciplinary

The chitosan hydrogels: from structure to function

Jing Fu et al.

NEW JOURNAL OF CHEMISTRY (2018)

Article Engineering, Biomedical

In Situ Forming Injectable Silk Fibroin Hydrogel Promotes Skin Regeneration in Full Thickness Burn Wounds

Dimple Chouhan et al.

ADVANCED HEALTHCARE MATERIALS (2018)

Article Nanoscience & Nanotechnology

Tough and Processable Hydrogels Based on Lignin and Hydrophilic Polyurethane

Farshad Oveissi et al.

ACS APPLIED BIO MATERIALS (2018)

Review Polymer Science

Functional Stimuli-Responsive Gels: Hydrogels and Microgels

Coro Echeverria et al.

Article Nanoscience & Nanotechnology

Functional self-healing materials and their potential applications in biomedical engineering

Jun Chen et al.

ADVANCED COMPOSITES AND HYBRID MATERIALS (2018)

Article Chemistry, Multidisciplinary

Hofmeister Effect-Assisted One Step Fabrication of Ductile and Strong Gelatin Hydrogels

Qingyan He et al.

ADVANCED FUNCTIONAL MATERIALS (2018)

Article Polymer Science

Thermo-rheological behaviour of native silk feedstocks

Peter R. Laity et al.

EUROPEAN POLYMER JOURNAL (2017)

Article Biochemistry & Molecular Biology

Artificial Auricular Cartilage Using Silk Fibroin and Polyvinyl Alcohol Hydrogel

Jung Min Lee et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Biochemistry & Molecular Biology

Silk Resin with Hydrated Dual Chemical-Physical Cross-Links Achieves High Strength and Toughness

Keiji Numata et al.

BIOMACROMOLECULES (2017)

Article Nanoscience & Nanotechnology

Enhancing Mechanical Properties of Silk Fibroin Hydrogel through Restricting the Growth of β-Sheet Domains

Dihan Su et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Review Chemistry, Multidisciplinary

Shape-Memory Hydrogels: Evolution of Structural Principles To Enable Shape Switching of Hydrophilic Polymer Networks

Candy Loewenberg et al.

ACCOUNTS OF CHEMICAL RESEARCH (2017)

Article Chemistry, Multidisciplinary

Physically Crosslinked Biocompatible Silk-Fibroin-Based Hydrogels with High Mechanical Performance

Kunyuan Luo et al.

ADVANCED FUNCTIONAL MATERIALS (2016)

Article Nanoscience & Nanotechnology

Injectable and pH-Responsive Silk Nanofiber Hydrogels for Sustained Anticancer Drug Delivery

Hongchun Wu et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

Review Engineering, Biomedical

Current advances and future perspectives in extrusion-based bioprinting

Ibrahim T. Ozbolat et al.

BIOMATERIALS (2016)

Article Materials Science, Biomaterials

Fabrication of robust Antheraea assama fibroin nanofibrous mat using ionic liquid for skin tissue engineering

Chandra Mohan Srivastava et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2016)

Article Materials Science, Biomaterials

Silk fibroin gelation via non-solvent induced phase separation

Naresh Kasoju et al.

BIOMATERIALS SCIENCE (2016)

Article Multidisciplinary Sciences

Research on the printability of hydrogels in 3D bioprinting

Yong He et al.

SCIENTIFIC REPORTS (2016)

Article Biochemistry & Molecular Biology

Gelation Behaviors and Mechanism of Silk Fibroin According to the Addition of Nitrate Salts

Dong Su Im et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article Biotechnology & Applied Microbiology

Processing Silk Hydrogel and Its Applications in Biomedical Materials

Hai-Yan Wang et al.

BIOTECHNOLOGY PROGRESS (2015)

Review Chemistry, Multidisciplinary

The chemistry and engineering of polymeric hydrogel adhesives for wound closure: a tutorial

C. Ghobril et al.

CHEMICAL SOCIETY REVIEWS (2015)

Article Biophysics

Silk structure and degradation

Bin Liu et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2015)

Review Chemistry, Multidisciplinary

Silk fibroin nanoparticle as a novel drug delivery system

Fatemeh Mottaghitalab et al.

JOURNAL OF CONTROLLED RELEASE (2015)

Article Materials Science, Biomaterials

Electromechanical response of silk fibroin hydrogel and conductive polycarbazole/silk fibroin hydrogel composites as actuator material

Thanida Srisawasdi et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2015)

Review Polymer Science

Structures, mechanical properties and applications of silk fibroin materials

Leng-Duei Koh et al.

PROGRESS IN POLYMER SCIENCE (2015)

Article Cell & Tissue Engineering

Cell Migration on Planar and Three-Dimensional Matrices: A Hydrogel-Based Perspective

Lucas T. Vu et al.

TISSUE ENGINEERING PART B-REVIEWS (2015)

Article Materials Science, Biomaterials

Polyol-Silk Bioink Formulations as Two-Part Room-Temperature Curable Materials for 3D Printing

Rod R. Jose et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2015)

Article Materials Science, Biomaterials

Polyol-Silk Bioink Formulations as Two-Part Room-Temperature Curable Materials for 3D Printing

Rod R. Jose et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2015)

Review Multidisciplinary Sciences

Hydrogel: Preparation, characterization, and applications: A review

Enas M. Ahmed

JOURNAL OF ADVANCED RESEARCH (2015)

Article Biochemistry & Molecular Biology

Effects of Synthetic Biomacromolecule Addition on the Flow Behavior of Concentrated Mesenchymal Cell Suspensions

Benoit G. C. Maisonneuve et al.

BIOMACROMOLECULES (2015)

Review Materials Science, Multidisciplinary

Mechanical characterisation of hydrogel materials

M. L. Oyen

INTERNATIONAL MATERIALS REVIEWS (2014)

Article Biochemistry & Molecular Biology

Silk-Pectin Hydrogel with Superior Mechanical Properties, Biodegradability, and Biocompatibility

Keiji Numata et al.

MACROMOLECULAR BIOSCIENCE (2014)

Article Materials Science, Biomaterials

Effects of substrate stiffness on adipogenic and osteogenic differentiation of human mesenchymal stem cells

Wen Zhao et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2014)

Article Cell & Tissue Engineering

Silk fibroin based hydrogel for regeneration of burn induced wounds

Hyung Woo Ju et al.

TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2014)

Article Multidisciplinary Sciences

Processing and characterisation of a novel electropolymerized silk fibroin hydrogel membrane

Hai-Yan Wang et al.

SCIENTIFIC REPORTS (2014)

Article Engineering, Biomedical

Silk hydrogels from non-mulberry and mulberry silkworm cocoons processed with ionic liquids

Simone S. Silva et al.

ACTA BIOMATERIALIA (2013)

Article Chemistry, Multidisciplinary

Silk Hydrogels as Soft Substrates for Neural Tissue Engineering

Amy M. Hopkins et al.

ADVANCED FUNCTIONAL MATERIALS (2013)

Article Engineering, Biomedical

The guidance of stem cell differentiation by substrate alignment and mechanical stimulation

Siddarth D. Subramony et al.

BIOMATERIALS (2013)

Article Biochemical Research Methods

Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength

Ludovic G. Vincent et al.

BIOTECHNOLOGY JOURNAL (2013)

Article Chemistry, Applied

Effect of methylcellulose on the formation and drug release behavior of silk fibroin hydrogel

Cho Hee Park et al.

CARBOHYDRATE POLYMERS (2013)

Article Materials Science, Composites

Swelling behaviours and mechanical properties of silk fibroin-polyurethane composite hydrogels

Yiping Huang et al.

COMPOSITES SCIENCE AND TECHNOLOGY (2013)

Article Materials Science, Biomaterials

Preparation and Characterization of Dual Phase Transition Oral Hydrogel for Sustained Release of Epirubicin

Hong-Ru Lin et al.

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS (2013)

Review Chemistry, Multidisciplinary

Poly(ethylene glycol)-poly(lactic-co-glycolic acid) based thermosensitive injectable hydrogels for biomedical applications

Amit Alexander et al.

JOURNAL OF CONTROLLED RELEASE (2013)

Article Biochemistry & Molecular Biology

Effect of Silk Protein Processing on Drug Delivery from Silk Films

Eleanor M. Pritchard et al.

MACROMOLECULAR BIOSCIENCE (2013)

Article Engineering, Biomedical

Sodium dodecyl sulfate-induced rapid gelation of silk fibroin

Xilong Wu et al.

ACTA BIOMATERIALIA (2012)

Review Chemistry, Multidisciplinary

Silk Materials - A Road to Sustainable High Technology

Hu Tao et al.

ADVANCED MATERIALS (2012)

Article Biochemistry & Molecular Biology

Synthetically Simple, Highly Resilient Hydrogels

Jun Cui et al.

BIOMACROMOLECULES (2012)

Article Engineering, Biomedical

Development and in-vivo characterization of supramolecular hydrogels for intrarenal drug delivery

Patricia Y. W. Dankers et al.

BIOMATERIALS (2012)

Review Chemistry, Physical

Peptide- and Protein-Based Hydrogels

Anika M. Jonker et al.

CHEMISTRY OF MATERIALS (2012)

Article Multidisciplinary Sciences

High-strength silk protein scaffolds for bone repair

Biman B. Mandal et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Materials Science, Multidisciplinary

Comparison of Gelation Time and Polyalcohol Effect on Hydrogels from Domestic and Wild Silk Fibroins

Huijing Zhao et al.

ADVANCES IN MATERIALS SCIENCE AND ENGINEERING (2012)

Proceedings Paper Materials Science, Multidisciplinary

The Gelation Study of Silk Fibroin for Biomedical Application

W. Rattanavises et al.

BIOMATERIALS AND APPLICATIONS (2012)

Article Biophysics

Elucidating the Role of Matrix Stiffness in 3D Cell Migration and Remodeling

M. Ehrbar et al.

BIOPHYSICAL JOURNAL (2011)

Article Polymer Science

Effect of Stereoregularity and Molecular Weight on the Mechanical Properties of Poly(vinyl alcohol) Hydrogel

Ryohei Fukae et al.

JOURNAL OF APPLIED POLYMER SCIENCE (2011)

Article Engineering, Biomedical

Concentrated collagen hydrogels as dermal substitutes

Christophe Helary et al.

BIOMATERIALS (2010)

Article Materials Science, Textiles

Silk Grafting with Chitosan and Crosslinking Agents

Franco Ferrero et al.

FIBERS AND POLYMERS (2010)

Review Chemistry, Analytical

Hydrogel-based devices for biomedical applications

Kosmas Deligkaris et al.

SENSORS AND ACTUATORS B-CHEMICAL (2010)

Review Chemistry, Multidisciplinary

Hydrogels in Regenerative Medicine

Brandon V. Slaughter et al.

ADVANCED MATERIALS (2009)

Article Engineering, Biomedical

Silk fibroin/polyacrylamide Semi-interpenetrating network hydrogels for controlled drug release

Biman B. Mandal et al.

BIOMATERIALS (2009)

Article Engineering, Biomedical

The effect of photopolymerization on stem cells embedded in hydrogels

Natalja E. Fedorovich et al.

BIOMATERIALS (2009)

Article Biophysics

Vortex-Induced Injectable Silk Fibroin Hydrogels

Tuna Yucel et al.

BIOPHYSICAL JOURNAL (2009)

Article Engineering, Biomedical

Sonication-induced gelation of silk fibroin for cell encapsulation

Xiaoqin Wang et al.

BIOMATERIALS (2008)

Article Chemistry, Physical

Photoluminescent single wall carbon nanotube-silica composite gels

Camilo Zamora-Ledezma et al.

CARBON (2008)

Review Gastroenterology & Hepatology

The role of matrix stiffness in regulating cell behavior

Rebecca G. Wells

HEPATOLOGY (2008)

Article Engineering, Biomedical

Fibroin/collagen hybrid hydrogels with crosslinking method: Preparation, properties, and cytocompatibility

Qiang Lv et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2008)

Article Engineering, Biomedical

Hydrogel biomaterials: A smart future?

Jindrich Kopecek

BIOMATERIALS (2007)

Article Chemistry, Physical

Mechanisms of silk fibroin sol-gel transitions

Akira Matsumoto et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2006)

Review Chemistry, Multidisciplinary

Hydrogels in biology and medicine: From molecular principles to bionanotechnology

Nicholas A. Peppas et al.

ADVANCED MATERIALS (2006)

Article Multidisciplinary Sciences

Characterizing the viscoelastic properties of thin hydrogel-based constructs for tissue engineering applications

M Ahearne et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2005)

Article Biochemistry & Molecular Biology

Swelling behavior and morphological evolution of mixed gelatin/silk fibroin hydrogels

ES Gil et al.

BIOMACROMOLECULES (2005)

Article Biochemistry & Molecular Biology

Structure and properties of silk hydrogels

UJ Kim et al.

BIOMACROMOLECULES (2004)

Article Engineering, Biomedical

Silk-based biomaterials

GH Altman et al.

BIOMATERIALS (2003)

Article Materials Science, Multidisciplinary

Characterizing viscoelastic properties of thin elastomeric membrane

BF Ju et al.

MECHANICS OF MATERIALS (2002)

Article Chemistry, Multidisciplinary

Heterogeneous structure of silk fibers from Bombyx mori resolved by 13C solid-state NMR spectroscopy

T Asakura et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

Article Engineering, Electrical & Electronic

Fabrication and characterization of hydrogel-based microvalves

RH Liu et al.

JOURNAL OF MICROELECTROMECHANICAL SYSTEMS (2002)

Article Engineering, Biomedical

Controlled release of vascular endothelial growth factor by use of collagen hydrogels

Y Tabata et al.

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2000)