Related references
Note: Only part of the references are listed.The PACAP pathway is independent of CGRP in mouse models of migraine: possible new drug target?
Charlotte Ernstsen et al.
BRAIN (2022)
Migraine evolution after the cessation of CGRP(-receptor) antibody prophylaxis: a prospective, longitudinal cohort study
Bianca Raffaelli et al.
CEPHALALGIA (2022)
Salivary CGRP can monitor the different migraine phases: CGRP (in)dependent attacks
Alicia Alpuente et al.
CEPHALALGIA (2022)
The chicken and egg problem: CGRP release due to trigeminal activation or vice versa?
Karl Messlinger
CEPHALALGIA (2022)
Calcitonin Gene Related Peptide, Adrenomedullin, and Adrenomedullin 2 Function in Uterine Artery During Human Pregnancy
Madhu Chauhan et al.
ENDOCRINOLOGY (2022)
Does wearing off of efficacy occur in galcanezumab-treated patients at the end of the monthly treatment cycle? Post hoc analyses of four phase III randomized trials
Jessica Ailani et al.
HEADACHE (2022)
Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles
Heidi Hautakangas et al.
NATURE GENETICS (2022)
Patient-reported outcomes of migraine treatment with erenumab: results from a national patient survey
Austeja Dapkute et al.
NEUROLOGICAL SCIENCES (2022)
Automated detection of squint as a sensitive assay of sex-dependent calcitonin gene-related peptide and amylin-induced pain in mice
Brandon J. Rea et al.
PAIN (2022)
Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice
Francesco De Logu et al.
NATURE COMMUNICATIONS (2022)
Constipation Caused by Anti-calcitonin Gene-Related Peptide Migraine Therapeutics Explained by Antagonism of Calcitonin Gene-Related Peptide's Motor-Stimulating and Prosecretory Function in the Intestine
Peter Holzer et al.
FRONTIERS IN PHYSIOLOGY (2022)
Alpha-Calcitonin Gene Related Peptide: New Therapeutic Strategies for the Treatment and Prevention of Cardiovascular Disease and Migraine
Ambrish Kumar et al.
FRONTIERS IN PHYSIOLOGY (2022)
Real-World Evidence for the Safety and Efficacy of CGRP Monoclonal Antibody Therapy Added to OnabotulinumtoxinA Treatment for Migraine Prevention in Adult Patients With Chronic Migraine
Laszlo Mechtler et al.
FRONTIERS IN NEUROLOGY (2022)
Neuroimmune regulatory networks of the airway mucosa in allergic inflammatory disease
E. Evonne Jean et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2022)
Beyond CGRP: The calcitonin peptide family as targets for migraine and pain
Tayla A. Rees et al.
BRITISH JOURNAL OF PHARMACOLOGY (2022)
Biological and small molecule strategies in migraine therapy with relation to the calcitonin gene-related peptide family of peptides
Lars Edvinsson et al.
BRITISH JOURNAL OF PHARMACOLOGY (2022)
CGRP receptor antagonists for migraine. Are they also AMY1 receptor antagonists?
Michael L. Garelja et al.
BRITISH JOURNAL OF PHARMACOLOGY (2022)
Pharmacological characterisation of mouse calcitonin and calcitonin receptor-like receptors reveals differences compared with human receptors
Michael L. Garelja et al.
BRITISH JOURNAL OF PHARMACOLOGY (2022)
Novel Macrocyclic Antagonists of the Calcitonin Gene-Related Peptide Receptor: Design, Realization, and Structural Characterization of Protein-Ligand Complexes
Andrew D. Cansfield et al.
ACS CHEMICAL NEUROSCIENCE (2022)
Activation of the trigeminal system as a likely target of SARS-CoV-2 may contribute to anosmia in COVID-19
Karl Messlinger et al.
CEPHALALGIA (2022)
Rapid resolution of migraine symptoms after initiating the preventive treatment eptinezumab during a migraine attack: results from the randomized RELIEF trial
Jessica Ailani et al.
BMC NEUROLOGY (2022)
The monoclonal CGRP-receptor blocking antibody erenumab has different effects on brainstem and cortical sensory-evoked responses
Francesco Casillo et al.
CEPHALALGIA (2022)
Calcitonin receptor antibody validation and expression in the rodent brain
Erica R. Hendrikse et al.
CEPHALALGIA (2022)
Excess neuropeptides in lung signal through endothelial cells to impair gas exchange
Jinhao Xu et al.
DEVELOPMENTAL CELL (2022)
Small molecule CGRP receptor antagonists for the preventive treatment of migraine: A review
Jessica Barreto Ribeiro dos Santos et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2022)
The use of erenumab for migraine prophylaxis during pregnancy: A case report and narrative review
Sierra J. Vig et al.
HEADACHE (2022)
Myocardial perfusion recovery induced by an α-calcitonin gene-related peptide analogue
Simon Bentsen et al.
JOURNAL OF NUCLEAR CARDIOLOGY (2022)
Pharmacological, Pharmacokinetic, Pharmacodynamic and Physicochemical Characterization of FE 205030: A Potent, Fast Acting, Injectable CGRP Receptor Antagonist for the Treatment of Acute Episodic Migraine
Karthik Srinivasan et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2022)
Changes in dorsal root ganglion CGRP expression in mouse pinch nerve injury model: Modulation by Somatostatin type-2 receptor
Qiong Xiang et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2022)
Calcitonin gene-related peptide-targeting drugs and Raynaud's phenomenon: a real-world potential safety signal from the WHO pharmacovigilance database
Alexandre O. Gerard et al.
JOURNAL OF HEADACHE AND PAIN (2022)
Characterization of erenumab and rimegepant on calcitonin gene-related peptide induced responses in Xenopus Laevis oocytes expressing the calcitonin gene-related peptide receptor and the amylin-1 receptor
Sanne Hage La Cour et al.
JOURNAL OF HEADACHE AND PAIN (2022)
CGRP-targeted drugs for migraine: still many uncertainties
Hans Christoph Diener
LANCET NEUROLOGY (2022)
Calcitonin gene-related peptide-targeting drugs for migraine: how pharmacology might inform treatment decisions
Linda Al-Hassany et al.
LANCET NEUROLOGY (2022)
Migraine monoclonal antibodies against CGRP change brain activity depending on ligand or receptor target - an fMRI study
Hauke Basedau et al.
ELIFE (2022)
Lipidated Calcitonin Gene-Related Peptide (CGRP) Peptide Antagonists Retain CGRP Receptor Activity and Attenuate CGRP Action In Vivo
Aqfan Jamaluddin et al.
FRONTIERS IN PHARMACOLOGY (2022)
The Neuropeptide α-Calcitonin Gene-Related Peptide as the Mediator of Beneficial Effects of Exercise in the Cardiovascular System
Tom Skaria et al.
FRONTIERS IN PHYSIOLOGY (2022)
CGRP and the Calcitonin Receptor are Co-Expressed in Mouse, Rat and Human Trigeminal Ganglia Neurons
Tayla A. Rees et al.
FRONTIERS IN PHYSIOLOGY (2022)
The Vascular-Dependent and -Independent Actions of Calcitonin Gene-Related Peptide in Cardiovascular Disease
Fulye Argunhan et al.
FRONTIERS IN PHYSIOLOGY (2022)
New Generation Gepants: Migraine Acute and Preventive Medications
David Moreno-Ajona et al.
JOURNAL OF CLINICAL MEDICINE (2022)
Probing Neuropeptide Volume Transmission In Vivo by Simultaneous Near-Infrared Light-Triggered Release and Optical Sensing
Hejian Xiong et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)
Is calcitonin gene-related peptide a reliable biochemical marker of migraine?
Betel Tesfay et al.
CURRENT OPINION IN NEUROLOGY (2022)
Characterization of transit rates in the large intestine of mice following treatment with a CGRP antibody, CGRP receptor antibody, and small molecule CGRP receptor antagonists
Kirk W. Johnson et al.
HEADACHE (2022)
Editors' Note: Effect of Levetiracetam Use Duration on Overall Survival of Isocitrate Dehydrogenase Wild-Type Glioblastoma in Adults: An Observational Study
Aravind Ganesh et al.
NEUROLOGY (2022)
Sex Differences in CGRP Regulation and Function in the Amygdala in a Rat Model of Neuropathic Pain
Peyton Presto et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2022)
Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection
Daping Yang et al.
CELL (2022)
From spreading depolarization to epilepsy with neuroinflammation: The role of CGRP in cortex
Fatima Gimeno-Ferrer et al.
EXPERIMENTAL NEUROLOGY (2022)
A phase IV clinical trial of gastrointestinal motility in adult patients with migraine before and after initiation of a calcitonin gene-related peptide ligand (galcanezumab) or receptor (erenumab) antagonist
David Kudrow et al.
HEADACHE (2022)
Anti-nociceptive effects of dual neuropeptide antagonist therapy in mouse model of neuropathic and inflammatory pain
Min Su Kim et al.
KOREAN JOURNAL OF PAIN (2022)
New and sex-specific migraine susceptibility loci identified from a multiethnic genome-wide meta-analysis
Helene Choquet et al.
COMMUNICATIONS BIOLOGY (2021)
CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells
Ashley J. Clark et al.
COMMUNICATIONS BIOLOGY (2021)
Acute Increase in Blood αCGRP at Maximal Exercise and Its Association to Cardiorespiratory Fitness, Carbohydrate Oxidation and Work Performed: An Exploratory Study in Young Men
Adolfo Aracil-Marco et al.
BIOLOGY-BASEL (2021)
Raynaud's phenomenon secondary to erenumab in a patient with chronic migraine
Agaath Hedina Manickam et al.
CLINICAL CASE REPORTS (2021)
Nociceptors protect sickle cell disease mice from vaso-occlusive episodes and chronic organ damage
Chunliang Xu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2021)
Different forms of traumatic brain injuries cause different tactile hypersensitivity profiles
Anne-Sophie Wattiez et al.
PAIN (2021)
CGRP Receptor Antagonism in COVID-19: Potential Cardiopulmonary Adverse Effects
Tom Skaria et al.
TRENDS IN MOLECULAR MEDICINE (2021)
Exploring the roles of neuropeptides in trigeminal neuropathic pain: A systematic review and narrative synthesis of animal studies
Nontawat Chuinsiri et al.
ARCHIVES OF ORAL BIOLOGY (2021)
Interictal amylin levels in chronic migraine patients: A case-control study
Pablo Irimia et al.
CEPHALALGIA (2021)
Combined onabotulinumtoxinA/atogepant treatment blocks activation/sensitization of high-threshold and wide-dynamic range neurons
Agustin Melo-Carrillo et al.
CEPHALALGIA (2021)
Was it something I ate? Understanding the bidirectional interaction of migraine and appetite neural circuits
Margarida Martins-Oliveira et al.
BRAIN RESEARCH (2021)
Hypertension: A new safety risk for patients treated with erenumab
Suprat Saely et al.
HEADACHE (2021)
Nociceptive nerves regulate haematopoietic stem cell mobilization
Xin Gao et al.
NATURE (2021)
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19
Jenny Meinhardt et al.
NATURE NEUROSCIENCE (2021)
Making headway - a role for CGRP in post-traumatic headache
Dimos D. Mitsikostas et al.
NATURE REVIEWS NEUROLOGY (2021)
Early outcomes of migraine after erenumab discontinuation: data from a real-life setting
Eleonora De Matteis et al.
NEUROLOGICAL SCIENCES (2021)
Area Postrema Cell Types that Mediate Nausea-Associated Behaviors
Chuchu Zhang et al.
NEURON (2021)
Increase in trigeminal ganglion neurons that respond to both calcitonin gene-related peptide and pituitary adenylate cyclase-activating polypeptide in mouse models of chronic migraine and posttraumatic headache
Zhaohua Guo et al.
PAIN (2021)
Inflammation in migraine ... or not ... : A critical evaluation of the evidence
Andrew Charles et al.
HEADACHE (2021)
Risk of hypertension in erenumab-treated patients with migraine: Analyses of clinical trial and postmarketing data
David W. Dodick et al.
HEADACHE (2021)
Airway stem cells sense hypoxia and differentiate into protective solitary neuroendocrine cells
Manjunatha Shivaraju et al.
SCIENCE (2021)
miR-34a-5p up-regulates the IL-1β/COX2/PGE2 inflammation pathway and induces the release of CGRP via inhibition of SIRT1 in rat trigeminal ganglion neurons
Hui Zhang et al.
FEBS OPEN BIO (2021)
Discontinuing monoclonal antibodies targeting CGRP pathway after one-year treatment: an observational longitudinal cohort study
Fabrizio Vernieri et al.
JOURNAL OF HEADACHE AND PAIN (2021)
Inflammatory complications of CGRP monoclonal antibodies: a case series
Jason C. Ray et al.
JOURNAL OF HEADACHE AND PAIN (2021)
Amylin antibodies frequently display cross-reactivity with CGRP: characterization of eight amylin antibodies
Tayla A. Rees et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2021)
A Monoclonal Anti-Calcitonin Gene-Related Peptide Antibody Decreases Stress-Induced Colonic Hypersensitivity
Ehsan Noor-Mohammadi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2021)
Migraine therapeutics differentially modulate the CGRP pathway
Minoti Bhakta et al.
CEPHALALGIA (2021)
CGRP monoclonal antibody prevents the loss of diffuse noxious inhibitory controls (DNIC) in a mouse model of post-traumatic headache
Caroline M. Kopruszinski et al.
CEPHALALGIA (2021)
Real-world efficacy, tolerability, and safety of ubrogepant
Chia-Chun Chiang et al.
HEADACHE (2021)
Convergence of peptidergic and non-peptidergic protein markers in the human dorsal root ganglion and spinal dorsal horn
Stephanie Shiers et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2021)
Delta opioid receptor regulation of calcitonin gene-related peptide dynamics in the trigeminal complex
Laura S. Moye et al.
PAIN (2021)
Efficacy and Tolerability of Calcitonin Gene-Related Peptide-Targeted Monoclonal Antibody Medications as Add-on Therapy to OnabotulinumtoxinA in Patients with Chronic Migraine
Fred Cohen et al.
PAIN MEDICINE (2021)
GFRAL-expressing neurons suppress food intake via aversive pathways
Paul Sabatini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Structure and dynamics of the CGRP receptor in apo and peptide-bound forms
Tracy M. Josephs et al.
SCIENCE (2021)
Sensory neurons expressing calcitonin gene-related peptide a regulate adaptive thermogenesis and diet-induced obesity
Kuldeep Makwana et al.
MOLECULAR METABOLISM (2021)
Amylin Analog Pramlintide Induces Migraine-like Attacks in Patients
Hashmat Ghanizada et al.
ANNALS OF NEUROLOGY (2021)
Transient Receptor Potential Channel 4 Small-Molecule Inhibition Alleviates Migraine-Like Behavior in Mice
Cinder Faith Cohen et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2021)
Pharmacokinetics and safety of ubrogepant when coadministered with calcitonin gene-related peptide-targeted monoclonal antibody migraine preventives in participants with migraine: A randomized phase 1b drug-drug interaction study
Abhijeet Jakate et al.
HEADACHE (2021)
A link between gastrointestinal disorders and migraine: Insights into the gut-brain connection
Sheena K. Aurora et al.
HEADACHE (2021)
Excitatory Effects of Calcitonin Gene-Related Peptide (CGRP) on Superficial Sp5C Neurons in Mouse Medullary Slices
Fang Zheng et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Effects of Calcitonin-Gene-Related-Peptide on Auditory Nerve Activity
Colleen G. Le Prell et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Do anti-CGRP drugs have a role in migraine aura therapy?
Eleonora Matteo et al.
JOURNAL OF NEUROLOGY (2021)
PACAP Induces Light Aversion in Mice by an Inheritable Mechanism Independent of CGRP
Adisa Kuburas et al.
JOURNAL OF NEUROSCIENCE (2021)
AM833 is a novel agonist of calcitonin family G protein-coupled receptors: pharmacological comparison to six selective and non-selective agonists
Madeleine M. Fletcher et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2021)
Migraine: disease characterisation, biomarkers, and precision medicine
Messoud Ashina et al.
LANCET (2021)
Effect of Adrenomedullin on Migraine-Like Attacks in Patients With Migraine A Randomized Crossover Study
Hashmat Ghanizada et al.
NEUROLOGY (2021)
Opening of BKCa channels causes migraine attacks: a new downstream target for the treatment of migraine
Mohammad Al-Mahdi Al-Karagholi et al.
PAIN (2021)
Real-World Evidence for Control of Chronic Migraine Patients Receiving CGRP Monoclonal Antibody Therapy Added to OnabotulinumtoxinA: A Retrospective Chart Review
Andrew M. Blumenfeld et al.
PAIN AND THERAPY (2021)
Evaluation of the Safety of Calcitonin Gene-Related Peptide Antagonists for Migraine Treatment Among Adults With Raynaud Phenomenon
Ilana D. Breen et al.
JAMA NETWORK OPEN (2021)
To Probe the Binding Interactions between Two FDA Approved Migraine Drugs (Ubrogepant and Rimegepant) and Calcitonin-Gene Related Peptide Receptor (CGRPR) Using Molecular Dynamics Simulations
Lauren Leung et al.
ACS CHEMICAL NEUROSCIENCE (2021)
Response to letter to the Editor: Assessing migraine therapeutics
Kimberly D. Mackenzie et al.
CEPHALALGIA (2021)
CGRP measurements in human plasma - a methodological study
Karl Messlinger et al.
CEPHALALGIA (2021)
Safety and tolerability evaluation of erenumab for the preventive treatment of migraine
Christina Deligianni et al.
EXPERT OPINION ON DRUG SAFETY (2021)
HMGB1, NLRP3, IL-6 and ACE2 levels are elevated in COVID-19 with headache: a window to the infection-related headache mechanism
Hayrunnisa Bolay et al.
JOURNAL OF HEADACHE AND PAIN (2021)
Role of CGRP pathway polymorphisms in migraine: a systematic review and impact on CGRP mAbs migraine therapy
Damiana Scuteri et al.
JOURNAL OF HEADACHE AND PAIN (2021)
CGRP outflow into jugular blood and cerebrospinal fluid and permeance for CGRP of rat dura mater
Miriam Risch et al.
JOURNAL OF HEADACHE AND PAIN (2021)
Migraine and neuroinflammation: the inflammasome perspective
Oguzhan Kursun et al.
JOURNAL OF HEADACHE AND PAIN (2021)
Cytokine and interleukin profile in patients with headache and COVID-19: A pilot, CASE-control, study on 104 patients
Javier Trigo et al.
JOURNAL OF HEADACHE AND PAIN (2021)
Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges
David Schafflick et al.
NATURE NEUROSCIENCE (2021)
Hormonal influences in migraine - interactions of oestrogen, oxytocin and CGRP
Diana N. Krause et al.
NATURE REVIEWS NEUROLOGY (2021)
Atogepant for the Preventive Treatment of Migraine
Jessica Ailani et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Contribution of dorsal horn CGRP-expressing interneurons to mechanical sensitivity
Line S. Loken et al.
ELIFE (2021)
Mammalian Neuronal mRNA Transport Complexes: The Few Knowns and the Many Unknowns
Elsa C. Rodrigues et al.
FRONTIERS IN INTEGRATIVE NEUROSCIENCE (2021)
Efficacy of Erenumab in the Treatment of Trigeminal Neuralgia A Retrospective Case Series
Eliot Parascandolo et al.
NEUROLOGY-CLINICAL PRACTICE (2021)
Headaches associated with acute SARS-CoV-2 infection: A prospective cross-sectional study
Delon D. Souza et al.
SAGE OPEN MEDICINE (2021)
Differential Synovial CGRP/RAMP1 Expression in Men and Women With Knee OsteoarthritisYoshihisa
Kentaro Uchida et al.
CUREUS JOURNAL OF MEDICAL SCIENCE (2021)
Effect of Adrenomedullin on Migraine-Like Attacks in Patients With Migraine
Hashmat Ghanizada et al.
NEUROLOGY (2021)
Tolerability of eptinezumab in overweight, obese or type 1 diabetes patients
Brian Baker et al.
ENDOCRINOLOGY DIABETES & METABOLISM (2021)
A Bidirectional View of Migraine and Diet Relationship
Parisa Gazerani
NEUROPSYCHIATRIC DISEASE AND TREATMENT (2021)
Neurobiology of SARS-CoV-2 interactions with the peripheral nervous system: implications for COVID-19 and pain
Amelia J. McFarland et al.
PAIN REPORTS (2021)
CGRP derived from cardiac fibroblasts is an endogenous suppressor of cardiac fibrosis
Wenqun Li et al.
CARDIOVASCULAR RESEARCH (2020)
Receptor component protein, an endogenous allosteric modulator of family B G protein coupled receptors
Sarah J. Routledge et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2020)
Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense
Nicole Y. Lai et al.
CELL (2020)
Contribution of intraganglionic CGRP to migraine-like responses in male and female rats
Erika Ivanna Araya et al.
CEPHALALGIA (2020)
Fluorescently-labeled fremanezumab is distributed to sensory and autonomic ganglia and the dura but not to the brain of rats with uncompromised blood brain barrier
Rodrigo Noseda et al.
CEPHALALGIA (2020)
Phase 3 randomized, placebo-controlled study of galcanezumab in patients with chronic cluster headache: Results from 3-month double-blind treatment
David W. Dodick et al.
CEPHALALGIA (2020)
Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury
Dara Bree et al.
CEPHALALGIA (2020)
CGRP in rat mesenteric artery and vein - receptor expression, CGRP presence and potential roles
Thi Lisa Le et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2020)
Gut-brain Axis and migraine headache: a comprehensive review
Mahsa Arzani et al.
JOURNAL OF HEADACHE AND PAIN (2020)
Expression of the CGRP Family of Neuropeptides and their Receptors in the Trigeminal Ganglion
Lars Edvinsson et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2020)
Cross-talk signaling in the trigeminal ganglion: role of neuropeptides and other mediators
Karl Messlinger et al.
JOURNAL OF NEURAL TRANSMISSION (2020)
Characterization of Ubrogepant: A Potent and Selective Antagonist of the Human Calcitonin Gene-Related Peptide Receptor
Eric Moore et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2020)
Potential for treatment benefit of small molecule CGRP receptor antagonist plus monoclonal antibody in migraine therapy
Kathleen Mullin et al.
NEUROLOGY (2020)
Lasmiditan inhibits calcitonin gene-related peptide release in the rodent trigeminovascular system
Alejandro Labastida-Ramirez et al.
PAIN (2020)
Low-dose interleukin-2 reverses behavioral sensitization in multiple mouse models of headache disorders
Jintao Zhang et al.
PAIN (2020)
Neuropeptides in gut-brain axis and their influence on host immunity and stress
Pingli Wei et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2020)
Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab)
Fernando Garces et al.
CELL REPORTS (2020)
Amylin/Calcitonin Receptor-Mediated Signaling in POMC Neurons Influences Energy Balance and Locomotor Activity in Chow-Fed Male Mice
Bernd Coester et al.
DIABETES (2020)
The effects of CGRP in vascular tissue - Classical vasodilation, shadowed effects and systemic dilemmas
Iben Sohn et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2020)
Palatable food access impacts expression of amylin receptor components in the mesocorticolimbic system
Houda Nashawi et al.
EXPERIMENTAL PHYSIOLOGY (2020)
Two-Hour CGRP Infusion Causes Gastrointestinal Hyperactivity: Possible Relevance for CGRP Antibody Treatment
Katrine Falkenberg et al.
HEADACHE (2020)
Could CGRP Antagonists Be Helpful in the Fight Against COVID-19?
Carrie E. Robertson
HEADACHE (2020)
Serotonin and Neuropeptides in Blood From Episodic and Chronic Migraine and Cluster Headache Patients in Case-Control and Case-Crossover Settings: A Systematic Review and Meta-Analysis
Simona D. Frederiksen et al.
HEADACHE (2020)
Dual Therapy With Anti-CGRP Monoclonal Antibodies and Botulinum Toxin for Migraine Prevention: Is There a Rationale?
Lanfranco Pellesi et al.
HEADACHE (2020)
Transient Receptor Potential Channels and Inflammatory Bowel Disease
Yiding Chen et al.
FRONTIERS IN IMMUNOLOGY (2020)
Cortical potentiation induced by calcitonin gene-related peptide (CGRP) in the insular cortex of adult mice
Yinglu Liu et al.
MOLECULAR BRAIN (2020)
The Effect of Adding Calcitonin Gene-Related Peptide Monoclonal Antibodies to Onabotulinum Toxin A Therapy on Headache Burden: A Retrospective Observational Case Series
Seniha N. Ozudogru et al.
HEADACHE (2020)
Stimulation of Posterior Thalamic Nuclei Induces Photophobic Behavior in Mice
Levi P. Sowers et al.
HEADACHE (2020)
Increased severity of closed head injury or repetitive subconcussive head impacts enhances post-traumatic headache-like behaviors in a rat model
Dara Bree et al.
CEPHALALGIA (2020)
The potential danger of blocking CGRP for treating migraine in CADASIL patients
Irene de Boer et al.
CEPHALALGIA (2020)
Low plasma levels of calcitonin gene-related peptide in persistent post-traumatic headache attributed to mild traumatic brain injury
Hakan Ashina et al.
CEPHALALGIA (2020)
Role of Calcitonin Gene-Related Peptide in Nociceptive Modulationin Anterior Cingulate Cortex of Naive Rats and Rats With Inflammatory Pain
Ke-Sai Hou et al.
FRONTIERS IN PHARMACOLOGY (2020)
Efficacy, tolerability, and safety of erenumab for the preventive treatment of persistent post-traumatic headache attributed to mild traumatic brain injury: an open-label study
Hakan Ashina et al.
JOURNAL OF HEADACHE AND PAIN (2020)
Structure-Based Drug Discovery of N-((R)-3-(7-Methyl-1H-indazol-5-yl)-1-oxo-1-(((S)-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2′-oxo-1′,2′-dihydrospiro[piperidine-4,4′-pyrido[2,3-d][1,3]oxazine]-1-carboxamide (HTL22562): A Calcitonin Gene-Related Peptide Receptor Antagonist for Acute Treatment of Migraine
Sarah J. Bucknell et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
A CGRP receptor antagonist peptide formulated for nasal administration to treat migraine
Bengt von Mentzer et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2020)
Hypersensitivity to Calcitonin Gene-Related Peptide in Post-Traumatic Headache
Hakan Ashina et al.
ANNALS OF NEUROLOGY (2020)
Preclinical studies investigating the neural mechanisms involved in the co-morbidity of migraine and temporomandibular disorders: the role of CGRP
Simon Akerman et al.
BRITISH JOURNAL OF PHARMACOLOGY (2020)
Vascular actions of peripheral CGRP in migraine-like photophobia in mice
Bianca N. Mason et al.
CEPHALALGIA (2020)
Emerging importance of satellite glia in nervous system function and dysfunction
Menachem Hanani et al.
NATURE REVIEWS NEUROSCIENCE (2020)
Quantitative differences in neuronal subpopulations between mouse and human dorsal root ganglia demonstrated with RNAscope in situ hybridization
Stephanie Shiers et al.
PAIN (2020)
Pharmacological treatment of migraine: CGRP and 5-HT beyond the triptans
Tessa de Vries et al.
PHARMACOLOGY & THERAPEUTICS (2020)
Targeting pituitary adenylate cyclase-activating polypeptide (PACAP) with monoclonal antibodies in migraine prevention: a brief review
Cecilia Rustichelli et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2020)
Safety of Rimegepant, an Oral CGRP Receptor Antagonist, Plus CGRP Monoclonal Antibodies for Migraine
Gary Berman et al.
HEADACHE (2020)
Real-World Patient Experience With Erenumab for the Preventive Treatment of Migraine
Jennifer Robblee et al.
HEADACHE (2020)
Cortical spreading depolarisation-induced facial hyperalgesia, photophobia and hypomotility are ameliorated by sumatriptan and olcegepant
Chunhua Tang et al.
SCIENTIFIC REPORTS (2020)
Plasma levels of CGRP and expression of specific microRNAs in blood cells of episodic and chronic migraine subjects: towards the identification of a panel of peripheral biomarkers of migraine?
Rosaria Greco et al.
JOURNAL OF HEADACHE AND PAIN (2020)
Headache characteristics in COVID-19 pandemic-a survey study
Ozge Uygun et al.
JOURNAL OF HEADACHE AND PAIN (2020)
Targeting CGRP in migraine: a matter of choice and dose
Linda Al-Hassany et al.
LANCET NEUROLOGY (2020)
Safety, tolerability, and efficacy of orally administered atogepant for the prevention of episodic migraine in adults: a double-blind, randomised phase 2b/3 trial
Peter J. Goadsby et al.
LANCET NEUROLOGY (2020)
Viral depletion of calcitonin receptors in the area postrema: A proof-of-concept study
Bernd Coester et al.
PHYSIOLOGY & BEHAVIOR (2020)
Antagonism of CGRP Signaling by Rimegepant at Two Receptors
Kylie S. Pan et al.
FRONTIERS IN PHARMACOLOGY (2020)
Giving Researchers a Headache - Sex and Gender Differences in Migraine
Linda Al-Hassany et al.
FRONTIERS IN NEUROLOGY (2020)
Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors
Michael L. Garelja et al.
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2020)
Distinct Patterns of Internalization of Different Calcitonin GeneRelated Peptide Receptors
Joseph J. Gingell et al.
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2020)
Sustained TNF-α stimulation leads to transcriptional memory that greatly enhances signal sensitivity and robustness
Zuodong Zhao et al.
ELIFE (2020)
Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine
Caroline M. Kopruszinski et al.
CEPHALALGIA (2020)
Headache associated with COVID-19: Frequency, characteristics and association with anosmia and ageusia
Pedro Augusto Sampaio Rocha-Filho et al.
CEPHALALGIA (2020)
Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia
Lucia M. Moreira et al.
NATURE (2020)
Induction of calcitonin gene-related peptide expression in rats by cortical spreading depression
Yan Wang et al.
CEPHALALGIA (2019)
Perivascular neurotransmitters: Regulation of cerebral blood flow and role in primary headaches
Simona D. Frederiksen et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2019)
Protease activated receptor 2 (PAR2) activation causes migraine-like pain behaviors in mice
Shayne N. Hassler et al.
CEPHALALGIA (2019)
Current understanding of meningeal and cerebral vascular function underlying migraine headache
Dan Levy et al.
CEPHALALGIA (2019)
The role of the brainstem in migraine: Potential brainstem effects of CGRP and CGRP receptor activation in animal models
Philip Robert Holland et al.
CEPHALALGIA (2019)
Cortical spreading depression as a site of origin for migraine: Role of CGRP
Liesl N. Close et al.
CEPHALALGIA (2019)
Molecular studies of CGRP and the CGRP family of peptides in the central nervous system
Erica R. Hendrikse et al.
CEPHALALGIA (2019)
Current understanding of trigeminal ganglion structure and function in headache
Karl Messlinger et al.
CEPHALALGIA (2019)
Adrenomedullin: Continuing to explore cardioprotection
Toshihiro Tsuruda et al.
PEPTIDES (2019)
Dual-specificity MAP kinase phosphatases in health and disease
Ole-Morten Seternes et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2019)
Current understanding of thalamic structure and function in migraine
Samaira Younis et al.
CEPHALALGIA (2019)
Calcitonin gene-related peptide potentiated the excitatory transmission and network propagation in the anterior cingulate cortex of adult mice
Xu-Hui Li et al.
MOLECULAR PAIN (2019)
Role of intraganglionic transmission in the trigeminovascular pathway
LuJuan Zhang et al.
MOLECULAR PAIN (2019)
A Mast-Cell-Specific Receptor Mediates Neurogenic Inflammation and Pain
Dustin P. Green et al.
NEURON (2019)
PACAP-38 and PACAP(6-38) Degranulate Rat Meningeal Mast Cells via the Orphan MrgB3-Receptor
Sara Hougaard Pedersen et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Peripheral and central nervous system distribution of the CGRP neutralizing antibody [125I] galcanezumab in male rats
Kirk W. Johnson et al.
CEPHALALGIA (2019)
Exploration of purinergic receptors as potential anti-migraine targets using established pre-clinical migraine models
Kristian A. Haanes et al.
CEPHALALGIA (2019)
Calcitonin Gene-Related Peptide Modulators - The History and Renaissance of a New Migraine Drug Class
Richard Hargreaves et al.
HEADACHE (2019)
Effects of monoclonal antagonist antibodies on calcitonin gene-related peptide receptor function and trafficking
Raffi Manoukian et al.
JOURNAL OF HEADACHE AND PAIN (2019)
CSD-Induced Arterial Dilatation and Plasma Protein Extravasation Are Unaffected by Fremanezumab: Implications for CGRP's Role in Migraine with Aura
Aaron J. Schain et al.
JOURNAL OF NEUROSCIENCE (2019)
Dural Calcitonin Gene-Related Peptide Produces Female-Specific Responses in Rodent Migraine Models
Amanda Avona et al.
JOURNAL OF NEUROSCIENCE (2019)
Opening of ATP-sensitive potassium channels causes migraine attacks: a new target for the treatment of migraine
Mohammad Al-Mahdi Al-Karagholi et al.
BRAIN (2019)
Calcitonin gene-related peptide levels in tear fluid are elevated in migraine patients compared to healthy controls
Katharina Kamm et al.
CEPHALALGIA (2019)
Raynaud's Phenomenon Associated With Calcitonin Gene-Related Peptide Monoclonal Antibody Antagonists
Randolph W. Evans
HEADACHE (2019)
Ischemic Stroke Associated With Calcitonin Gene-Related Peptide Inhibitor Therapy for Migraine: A Case Report
Stephen Aradi et al.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2019)
Does inflammation have a role in migraine?
Lars Edvinsson et al.
NATURE REVIEWS NEUROLOGY (2019)
Trial of Galcanezumab in Prevention of Episodic Cluster Headache
Peter J. Goadsby et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Role of Dual-Specificity Phosphatase 1 in Glucocorticoid-Driven Anti-inflammatory Responses
Jessica Hoppstaedter et al.
FRONTIERS IN IMMUNOLOGY (2019)
Amylin as a potential link between type 2 diabetes and alzheimer disease
Ivan Martinez-Valbuena et al.
ANNALS OF NEUROLOGY (2019)
Hypothalamic regulation of headache and migraine
Arne May et al.
CEPHALALGIA (2019)
CGRP-dependent and independent mechanisms of acute and persistent post-traumatic headache following mild traumatic brain injury in mice
Edita Navratilova et al.
CEPHALALGIA (2019)
Migraine and the trigeminovascular system-40 years and counting
Messoud Ashina et al.
LANCET NEUROLOGY (2019)
The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology
Karin Warfvinge et al.
PHARMACOLOGY (2019)
Identifying roles for peptidergic signaling in mice
Kathryn G. Powers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Physiological signaling in the absence of amidated peptides
Iris Lindberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraine
Jeanine L. Bussiere et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2019)
A Popperian View on Anti-CGRP Biologics in Migraine
Alberto Chiarugi
HEADACHE (2019)
C-fibers may modulate adjacent Aδ-fibers through axon-axon CGRP signaling at nodes of Ranvier in the trigeminal system
Jacob C. A. Edvinsson et al.
JOURNAL OF HEADACHE AND PAIN (2019)
Targeting calcitonin gene-related peptide: a new era in migraine therapy
Andrew Charles et al.
LANCET (2019)
Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache
Caroline Bonnet et al.
NATURE COMMUNICATIONS (2019)
Neuropeptides in sensory signal processing
Richard Carr et al.
CELL AND TISSUE RESEARCH (2019)
CGRP ligand and receptor monoclonal antibodies for migraine prevention: Evidence review and clinical implications
David W. Dodick
CEPHALALGIA (2019)
Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms
Clemens Schafmayer et al.
GUT (2019)
Biomarkers in Migraine Headache: Prognostic and Therapeutic Implications
Patrizia Ferroni et al.
CURRENT MEDICINAL CHEMISTRY (2019)
Novel hypotheses emerging from GWAS in migraine?
Arn M. J. M. van den Maagdenberg et al.
JOURNAL OF HEADACHE AND PAIN (2019)
An Intraperitoneal Treatment with Calcitonin Gene-Related Peptide (CGRP) Regulates Appetite, Energy Intake/Expenditure, and Metabolism
Daniel Sanford et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2019)
New Insights into the Regulation of CGRP-Family Receptors
Joseph J. Gingell et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2019)
CGRP-CRLR/RAMP1 signal is important for stress-induced hematopoiesis
Akira Suekane et al.
SCIENTIFIC REPORTS (2019)
CGRP Is Critical for Hot Flushes in Ovariectomized Mice
Daniel B. Wilhelms et al.
FRONTIERS IN PHARMACOLOGY (2019)
Distribution of CGRP and CGRP receptor components in the rat brain
Karin Warfvinge et al.
CEPHALALGIA (2019)
CGRP receptor antagonist MK-8825 attenuates cortical spreading depression induced pain behavior
Asli Filiz et al.
CEPHALALGIA (2019)
CGRP-Based Migraine Therapeutics: How Might They Work, Why So Safe, and What Next?
Andrew F. Russo
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2019)
New discoveries in migraine mechanisms and therapeutic targets
Greg Dussor
CURRENT OPINION IN PHYSIOLOGY (2019)
Development of CGRP-dependent pain and headache related behaviours in a rat model of concussion: Implications for mechanisms of post-traumatic headache
Dara Bree et al.
CEPHALALGIA (2018)
Activation of pial and dural macrophages and dendritic cells by cortical spreading depression
Aaron J. Schain et al.
ANNALS OF NEUROLOGY (2018)
Pituitary adenylate-cyclase-activating polypeptide (PACAP): another novel target for treatment of primary headaches?
Messoud Ashina et al.
JOURNAL OF HEADACHE AND PAIN (2018)
Characterization of signalling and regulation of common calcitonin receptor splice variants and polymorphisms
Emma Dal Maso et al.
BIOCHEMICAL PHARMACOLOGY (2018)
TRPA1/NOX in the soma of trigeminal ganglion neurons mediates migraine-related pain of glyceryl trinitrate in mice
Ilaria Maddalena Marone et al.
BRAIN (2018)
Transcriptomic profiling of trigeminal nucleus caudalis and spinal cord dorsal horn
Lisette J. A. Kogelman et al.
BRAIN RESEARCH (2018)
Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition
Jes Olesen
CEPHALALGIA (2018)
Calcitonin receptors are ancient modulators for rhythms of preferential temperature in insects and body temperature in mammals
Tadahiro Goda et al.
GENES & DEVELOPMENT (2018)
Effects of Calcitonin Gene-Related Peptide on Colonic Motility and Defecation in Conscious Dogs
Tomoyuki Ono et al.
JOURNAL OF GASTROINTESTINAL SURGERY (2018)
PACAP and its role in primary headaches
Lars Edvinsson et al.
JOURNAL OF HEADACHE AND PAIN (2018)
Feasibility of serum CGRP measurement as a biomarker of chronic migraine: a critical reappraisal
Mi Ji Lee et al.
JOURNAL OF HEADACHE AND PAIN (2018)
CGRP as the target of new migraine therapies - successful translation from bench to clinic
Lars Edvinsson et al.
NATURE REVIEWS NEUROLOGY (2018)
Targeted Orexin and Hypothalamic Neuropeptides for Migraine
Lauren C. Strother et al.
NEUROTHERAPEUTICS (2018)
Glutamate and Its Receptors as Therapeutic Targets for Migraine
Jan Hoffmann et al.
NEUROTHERAPEUTICS (2018)
Comparative transcriptome profiling of the human and mouse dorsal root ganglia: an RNA-seq-based resource for pain and sensory neuroscience research
Pradipta Ray et al.
PAIN (2018)
Peripherally administered calcitonin gene-related peptide induces spontaneous pain in mice: implications for migraine
Brandon J. Rea et al.
PAIN (2018)
Pulmonary neuroendocrine cells amplify allergic asthma responses
Pengfei Sui et al.
SCIENCE (2018)
The Parabrachial Nucleus: CGRP Neurons Function as a General Alarm
Richard D. Palmiter
TRENDS IN NEUROSCIENCES (2018)
Who Should Try New Antibody Treatments for Migraine?
Elizabeth W. Loder et al.
JAMA NEUROLOGY (2018)
Cryo-EM structure of the active, G(s)- protein complexed, human CGRP receptor
Yi-Lynn Liang et al.
NATURE (2018)
Encoding of danger by parabrachial CGRP neurons
Carlos A. Campos et al.
NATURE (2018)
CGRP blockade by galcanezumab was not associated with reductions in signs and symptoms of knee osteoarthritis in a randomized clinical trial
Y. Jin et al.
OSTEOARTHRITIS AND CARTILAGE (2018)
Therapeutic Targeting of Endosomal G-Protein-Coupled Receptors
Alex R. B. Thomsen et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Vascular Contributions to Migraine: Time to Revisit?
Bianca N. Mason et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2018)
Loss of α-Calcitonin Gene-Related Peptide (αCGRP) Reduces Otolith Activation Timing Dynamics and Impairs Balance
Sherri M. Jones et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
The Role of Calcitonin Gene Related Peptide (CGRP) in Neurogenic Vasodilation and Its Cardioprotective Effects
Zizheng Kee et al.
FRONTIERS IN PHYSIOLOGY (2018)
Migraine induction with calcitonin gene-related peptide in patients from erenumab trials
Casper Emil Christensen et al.
JOURNAL OF HEADACHE AND PAIN (2018)
Parabrachial CGRP Neurons Establish and Sustain Aversive Taste Memories
Jane Y. Chen et al.
NEURON (2018)
Expression of Pituitary Adenylate Cyclase-activating Peptide, Calcitonin Gene-related Peptide and Headache Targets in the Trigeminal Ganglia of Rats and Humans
Simona Denise Frederiksen et al.
NEUROSCIENCE (2018)
CGRP receptor antagonist activity of olcegepant depends on the signalling pathway measured
Christopher S. Walker et al.
CEPHALALGIA (2018)
Molecular Signature for Receptor Engagement in the Metabolic Peptide Hormone Amylin
Rebekah L. Bower et al.
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2018)
Adrenomedullin 2/intermedin: a putative drug candidate for treatment of cardiometabolic diseases
Song-Yang Zhang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Co-expression of the calcitonin receptor gene in the hypothalamic kisspeptin neurons in female rats
Assadullah et al.
REPRODUCTIVE MEDICINE AND BIOLOGY (2018)
Serum calcitonin gene-related peptide facilitates adipose tissue lipolysis during exercise via PIPLC/IP3 pathways
Malihe Aveseh et al.
ENDOCRINE (2018)
Neuropeptides in asthma, chronic obstructive pulmonary disease and cystic fibrosis
Kalina R. Atanasova et al.
RESPIRATORY RESEARCH (2018)
Update on the pharmacology of calcitonin/CGRP family of peptides: IUPHAR Review 25
Debbie L. Hay et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Migraine biomarkers in cerebrospinal fluid: A systematic review and meta-analysis
Robin M. van Dongen et al.
CEPHALALGIA (2017)
Sex-, stress-, and sympathetic post-ganglionic-dependent changes in identity and proportions of immune cells in the dura
Lisa A. McIlvried et al.
CEPHALALGIA (2017)
Integrative concepts of rosacea pathophysiology, clinical presentation and new therapeutics
Anna D. Holmes et al.
EXPERIMENTAL DERMATOLOGY (2017)
Induction of Migraine-Like Photophobic Behavior in Mice by Both Peripheral and Central CGRP Mechanisms
Bianca N. Mason et al.
JOURNAL OF NEUROSCIENCE (2017)
Endogenous Calcitonin Gene-Related Peptide Regulates Lipid Metabolism and Energy Homeostasis in Male Mice
Tian Liu et al.
ENDOCRINOLOGY (2017)
Possible role of calcitonin gene-related peptide in trigeminal modulation of glomerular microcircuits of the rodent olfactory bulb
Federica Genovese et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2017)
Overview of Neuropeptides: Awakening the Senses?
Andrew F. Russo
HEADACHE (2017)
Genetics of Migraine: Insights into the Molecular Basis of Migraine Disorders
Heidi G. Sutherland et al.
HEADACHE (2017)
Neuro-immune interactions in allergic diseases: novel targets for therapeutics
Tiphaine Voisin et al.
INTERNATIONAL IMMUNOLOGY (2017)
Calcitonin gene-related peptide and pain: a systematic review
Wendy Sophie Schou et al.
JOURNAL OF HEADACHE AND PAIN (2017)
Blocking CGRP in migraine patients - a review of pros and cons
Marie Deen et al.
JOURNAL OF HEADACHE AND PAIN (2017)
Selective Inhibition of Trigeminovascular Neurons by Fremanezumab: A Humanized Monoclonal Anti-CGRP Antibody
Agustin Melo-Carrillo et al.
JOURNAL OF NEUROSCIENCE (2017)
Calcitonin Gene-Related Peptide Induces HIV-1 Proteasomal Degradation in Mucosal Langerhans Cells
Morgane Bomsel et al.
JOURNAL OF VIROLOGY (2017)
Understanding the molecular functions of the second extracellular loop (ECL2) of the calcitonin gene-related peptide (CGRP) receptor using a comprehensive mutagenesis approach
Michael J. Woolley et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2017)
Potentiation of NMDA receptor-mediated synaptic transmission at the parabrachial-central amygdala synapses by CGRP in mice
Yuya Okutsu et al.
MOLECULAR PAIN (2017)
Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus
Carlos A. Campos et al.
NATURE NEUROSCIENCE (2017)
Functional consequences of neuropeptide and small-molecule co-transmission
Michael P. Nusbaum et al.
NATURE REVIEWS NEUROSCIENCE (2017)
Anti-CGRP antibodies block CGRP-induced diarrhea in mice
Eric A. Kaiser et al.
NEUROPEPTIDES (2017)
LARGE DENSE-CORE VESICLE EXOCYTOSIS FROM MOUSE DORSAL ROOT GANGLION NEURONS IS REGULATED BY NEUROPEPTIDE Y
Anneka Bost et al.
NEUROSCIENCE (2017)
The role of calcitonin gene-related peptide in peripheral and central pain mechanisms including migraine
Smriti Iyengar et al.
PAIN (2017)
Differential effects of Calca-derived peptides in male mice with diet-induced obesity
Alexander Bartelt et al.
PLOS ONE (2017)
GPCRs globally coevolved with receptor activity-modifying proteins, RAMPs
Shahar Barbash et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission
Rebecca E. Yarwood et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Determination of stable reference genes for RT-qPCR expression data in mechanistic pain studies on pig dorsal root ganglia and spinal cord
Dale A. Sandercock et al.
RESEARCH IN VETERINARY SCIENCE (2017)
Reflex Modification Audiometry Reveals Dual Roles for Olivocochlear Neurotransmission
Paul D. Allen et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2017)
Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity
Renchao Chen et al.
CELL REPORTS (2017)
The Molecular Fingerprint of Dorsal Root and Trigeminal Ganglion Neurons
Douglas M. Lopes et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Amylin Acts in the Lateral Dorsal Tegmental Nucleus to Regulate Energy Balance Through Gamma-Aminobutyric Acid Signaling
David J. Reiner et al.
BIOLOGICAL PSYCHIATRY (2017)
Role of calcitonin gene-related peptide in energy metabolism
William Gustavo Lima et al.
ENDOCRINE (2017)
Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs
Michael J. Woolley et al.
BIOCHEMICAL PHARMACOLOGY (2017)
A Novel α-Calcitonin Gene-Related Peptide Analogue Protects Against End-Organ Damage in Experimental Hypertension, Cardiac Hypertrophy, and Heart Failure
Aisah A. Aubdool et al.
CIRCULATION (2017)
CGRP receptor activity in mice with global expression of human receptor activity modifying protein 1
Keegan J. Bohn et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Meningeal blood flow is controlled by H2S-NO crosstalk activating a HNO-TRPA1-CGRP signalling pathway
Maria Dux et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
Localization of CGRP receptor components and receptor binding sites in rhesus monkey brainstem: A detailed study using in situ hybridization, immunofluorescence, and autoradiography
Sajedeh Eftekhari et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2016)
Serum MicroRNA Signatures in Migraineurs During Attacks and in Pain-Free Periods
Hjalte H. Andersen et al.
MOLECULAR NEUROBIOLOGY (2016)
Mapping the calcitonin receptor in human brain stem
Rebekah L. Bower et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2016)
Receptor Activity-Modifying Proteins (RAMPs): New Insights and Roles
Debbie L. Hay et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 56 (2016)
Migraine photophobia originating in cone-driven retinal pathways
Rodrigo Noseda et al.
BRAIN (2016)
The endothelial adrenomedullin-RAMP2 system regulates vascular integrity and suppresses tumour metastasis
Megumu Tanaka et al.
CARDIOVASCULAR RESEARCH (2016)
Parabrachial CGRP Neurons Control Meal Termination
Carlos A. Campos et al.
CELL METABOLISM (2016)
Amylin receptor components and the leptin receptor are co-expressed in single rat area postrema neurons
Claudia G. Liberini et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2016)
Long acting analogue of the calcitonin gene-related peptide induces positive metabolic effects and secretion of the glucagon-like peptide-1
Cecilia Nilsson et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2016)
Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors
Cathryn Weston et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Vasculo-Neuronal Coupling: Retrograde Vascular Communication to Brain Neurons
Ki Jung Kim et al.
JOURNAL OF NEUROSCIENCE (2016)
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Padhraig Gormley et al.
NATURE GENETICS (2016)
A proposal for validation of antibodies
Mathias Uhlen et al.
NATURE METHODS (2016)
CONTRIBUTION OF SYNAPTIC PLASTICITY IN THE INSULAR CORTEX TO CHRONIC PAIN
Min Zhuo
NEUROSCIENCE (2016)
NEUROVASCULAR CONTRIBUTIONS TO MIGRAINE: MOVING BEYOND VASODILATION
Blaine Jacobs et al.
NEUROSCIENCE (2016)
IMMUNOHISTOCHEMICAL LOCALIZATION OF THE CALCITONIN GENE-RELATED PEPTIDE BINDING SITE IN THE PRIMATE TRIGEMINOVASCULAR SYSTEM USING FUNCTIONAL ANTAGONIST ANTIBODIES
Silke Miller et al.
NEUROSCIENCE (2016)
Premonitory and nonheadache symptoms induced by CGRP and PACAP38 in patients with migraine
Song Guo et al.
PAIN (2016)
Involvement of CGRP receptors in retinal spreading depression
Yan Wang et al.
PHARMACOLOGICAL REPORTS (2016)
Wiping Out CGRP: Potential Cardiovascular Risks
Antoinette MaassenVanDenBrink et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2016)
Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour
Masao Doi et al.
NATURE COMMUNICATIONS (2016)
Genetically and functionally defined NTS to PBN brain circuits mediating anorexia
Carolyn W. Roman et al.
NATURE COMMUNICATIONS (2016)
Pharmacologic Characterization of AMG 334, a Potent and Selective Human Monoclonal Antibody against the Calcitonin Gene-Related Peptide Receptor
Licheng Shi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)
Calcitonin Gene-Related Peptide (CGRP): A New Target for Migraine
Andrew F. Russo
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 55 (2015)
Localization of CGRP, CGRP receptor, PACAP and glutamate in trigeminal ganglion. Relation to the blood-brain barrier
Sajedeh Eftekhari et al.
BRAIN RESEARCH (2015)
CGRP receptor antagonists and antibodies against CGRP and its receptor in migraine treatment
Lars Edvinsson
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2015)
Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake
Zhiying Li et al.
CELL METABOLISM (2015)
Periaqueductal gray calcitonin gene-related peptide modulates trigeminovascular neurons
P. Pozo-Rosich et al.
CEPHALALGIA (2015)
Bench-to-bedside pharmacology of adrenomedullin
Johji Kato et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2015)
Experimental inflammation following dural application of complete Freund's adjuvant or inflammatory soup does not alter brain and trigeminal microvascular passage
Cornelia Lundblad et al.
JOURNAL OF HEADACHE AND PAIN (2015)
Migraine: Multiple Processes, Complex Pathophysiology
Rami Burstein et al.
JOURNAL OF NEUROSCIENCE (2015)
Parabrachial Calcitonin Gene-Related Peptide Neurons Mediate Conditioned Taste Aversion
Matthew E. Carter et al.
JOURNAL OF NEUROSCIENCE (2015)
Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor
Jason M. Booe et al.
MOLECULAR CELL (2015)
Evidence for orexinergic mechanisms in migraine
Jan Hoffmann et al.
NEUROBIOLOGY OF DISEASE (2015)
OnabotulinumtoxinA decreases interictal CGRP plasma levels in patients with chronic migraine
Eva Cernuda-Morollon et al.
PAIN (2015)
RNA-Seq Analysis of Human Trigeminal and Dorsal Root Ganglia with a Focus on Chemoreceptors
Caroline Flegel et al.
PLOS ONE (2015)
PROCALCITONIN LEVELS IN SURVIVORS AND NONSURVIVORS OF SEPSIS: SYSTEMATIC REVIEW AND META-ANALYSIS
Shubhangi Arora et al.
SHOCK (2015)
Clinical, Histologic, and Molecular Analysis of Differences Between Erythematotelangiectatic Rosacea and Telangiectatic Photoaging
Yolanda R. Helfrich et al.
JAMA DERMATOLOGY (2015)
Calcitonin gene-related peptide inhibits human immunodeficiency type 1 transmission by Langerhans cells via an autocrine/paracrine feedback mechanism
Y. Ganor et al.
ACTA PHYSIOLOGICA (2015)
Neurochemical properties of the synapses between the parabrachial nucleus-derived CGRP-positive axonal terminals and the GABAergic neurons in the lateral capsular division of central nucleus of amygdala
Ya-Cheng Lu et al.
MOLECULAR NEUROBIOLOGY (2015)
A second trigeminal CGRP receptor: function and expression of the AMY1 receptor
Christopher S. Walker et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2015)
Amylin: Pharmacology, Physiology, and Clinical Potential
Debbie L. Hay et al.
PHARMACOLOGICAL REVIEWS (2015)
Inverse neurovascular coupling to cortical spreading depolarizations in severe brain trauma
Jason M. Hinzman et al.
BRAIN (2014)
Structure-activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation
Debbie L. Hay et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
TRPV1 Pain Receptors Regulate Longevity and Metabolism by Neuropeptide Signaling
Celine E. Riera et al.
CELL (2014)
Glutamate Receptor Antagonists in the Management of Migraine
Kayi Chan et al.
DRUGS (2014)
Activity of Pramlintide, Rat and Human Amylin but not Aβ1-42 at Human Amylin Receptors
Joseph J. Gingell et al.
ENDOCRINOLOGY (2014)
Reactive Oxygen Species Induce Procalcitonin Expression in Trigeminal Ganglia Glia
Ann C. Raddant et al.
HEADACHE (2014)
An Ongoing Role of α-Calcitonin Gene-Related Peptide as Part of a Protective Network Against Hypertension, Vascular Hypertrophy, and Oxidative Stress
Sarah-Jane Smillie et al.
HYPERTENSION (2014)
Antipsychotic-Like Actions of the Satiety Peptide, Amylin, in Ventral Striatal Regions Marked by Overlapping Calcitonin Receptor and RAMP-1 Gene Expression
Sarah K. Baisley et al.
JOURNAL OF NEUROSCIENCE (2014)
Loss of α-Calcitonin Gene-Related Peptide (αCGRP) Reduces the Efficacy of the Vestibulo-ocular Reflex (VOR)
Anne E. Luebke et al.
JOURNAL OF NEUROSCIENCE (2014)
Multimodal Use of Calcitonin Gene-Related Peptide and Substance P in Itch and Acute Pain Uncovered by the Elimination of Vesicular Glutamate Transporter 2 from Transient Receptor Potential Cation Channel Subfamily V Member 1 Neurons
Katarzyna Rogoz et al.
JOURNAL OF NEUROSCIENCE (2014)
GluA1 Phosphorylation Contributes to Postsynaptic Amplification of Neuropathic Pain in the Insular Cortex
Shuang Qiu et al.
JOURNAL OF NEUROSCIENCE (2014)
Randomized controlled trial of the CGRP receptor antagonist telcagepant for migraine prevention
Tony W. Ho et al.
NEUROLOGY (2014)
mRNA distribution of CGRP and its receptor components in the trigeminovascular system and other pain related structures in rat brain, and effect of intracerebroventricular administration of CGRP on Fos expression in the TNC
Deepak Kumar Bhatt et al.
NEUROSCIENCE LETTERS (2014)
CALCITONIN GENE-RELATED PEPTIDE: PHYSIOLOGY AND PATHOPHYSIOLOGY
F. A. Russell et al.
PHYSIOLOGICAL REVIEWS (2014)
Development of a novel antibody to calcitonin gene-related peptide for the treatment of osteoarthritis-related pain
R. J. Benschop et al.
OSTEOARTHRITIS AND CARTILAGE (2014)
α-Calcitonin gene related peptide (α-CGRP) mediated lipid mobilization in 3T3-L1 adipocytes
Christopher S. Walker et al.
PEPTIDES (2014)
Heat Hyperalgesia and Mechanical Hypersensitivity Induced by Calcitonin Gene-Related Peptide in a Mouse Model of Neurofibromatosis
Stephanie White et al.
PLOS ONE (2014)
Neurochemical Pathways That Converge on Thalamic Trigeminovascular Neurons: Potential Substrate for Modulation of Migraine by Sleep, Food Intake, Stress and Anxiety
Rodrigo Noseda et al.
PLOS ONE (2014)
H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway
Mirjam Eberhardt et al.
NATURE COMMUNICATIONS (2014)
Calcitonin gene-related peptide is a key neurotransmitter in the neuro-immune axis
Bakri M. Assas et al.
FRONTIERS IN NEUROSCIENCE (2014)
Glutamate, Substance P, and Calcitonin Gene-Related Peptide Cooperate in Inflammation-Induced Heat Hyperalgesia
Katarzyna Rogoz et al.
MOLECULAR PHARMACOLOGY (2014)
Anxiogenic effects of CGRP within the BNST may be mediated by CRF acting at BNST CRFR1 receptors
K. S. Sink et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): A potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery
Prasad V. Chaturvedula et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Epigenetic mechanisms in migraine: a promising avenue?
Else Eising et al.
BMC MEDICINE (2013)
Receptor activity-modifying protein-dependent impairment of calcitonin receptor splice variant Δ(1-47)hCT(a) function
T. Qi et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
CGRP in the trigeminovascular system: a role for CGRP, adrenomedullin and amylin receptors?
C. S. Walker et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Structure-activity relationships for α-calcitonin gene-related peptide
Harriet A. Watkins et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Localization of CGRP Receptor Components, CGRP, and Receptor Binding Sites in Human and Rhesus Cerebellar Cortex
Sajedeh Eftekhari et al.
CEREBELLUM (2013)
Roles of CLR/RAMP Receptor Signaling in Reproduction and Development
Chia Lin Chang et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2013)
Neuropeptide receptors provide a signalling pathway for trigeminal modulation of olfactory transduction
Philipp Daiber et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2013)
Calcitonin gene-related peptide inhibits Langerhans cell-mediated HIV-1 transmission
Yonatan Ganor et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Changes in calcitonin gene-related peptide (CGRP) receptor component and nitric oxide receptor (sGC) immunoreactivity in rat trigeminal ganglion following glyceroltrinitrate pretreatment
Kristin Seiler et al.
JOURNAL OF HEADACHE AND PAIN (2013)
Epidermal Nerve Fibers Modulate Keratinocyte Growth via Neuropeptide Signaling in an Innervated Skin Model
Dennis Roggenkamp et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2013)
Differentiation of Nerve Fibers Storing CGRP and CGRP Receptors in the Peripheral Trigeminovascular System
Sajedeh Eftekhari et al.
JOURNAL OF PAIN (2013)
Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies
Shabana Vohra et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2013)
The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach
Michael. J. Woolley et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2013)
Genetic identification of a neural circuit that suppresses appetite
Matthew E. Carter et al.
NATURE (2013)
Cortical spreading depression and migraine
Andrew C. Charles et al.
NATURE REVIEWS NEUROLOGY (2013)
Interictal increase of CGRP levels in peripheral blood as a biomarker for chronic migraine
Eva Cernuda-Morollon et al.
NEUROLOGY (2013)
CGRP and migraine: Could PACAP play a role too?
Eric A. Kaiser et al.
NEUROPEPTIDES (2013)
CORTICAL SPREADING DEPRESSION INDUCES OXIDATIVE STRESS IN THE TRIGEMINAL NOCICEPTIVE SYSTEM
A. Shatillo et al.
NEUROSCIENCE (2013)
EVIDENCE FOR ANTI-INFLAMMATORY AND PUTATIVE ANALGESIC EFFECTS OF A MONOCLONAL ANTIBODY TO CALCITONIN GENE-RELATED PEPTIDE
K. E. Bowler et al.
NEUROSCIENCE (2013)
The CGRP receptor antagonist BIBN4096BS peripherally alleviates inflammatory pain in rats
Silke Hirsch et al.
PAIN (2013)
Comprehensive RNA-Seq Expression Analysis of Sensory Ganglia with a Focus on Ion Channels and GPCRs in Trigeminal Ganglia
Stavros Manteniotis et al.
PLOS ONE (2013)
Selective CGRP and adrenomedullin peptide binding by tethered RAMP-calcitonin receptor-like receptor extracellular domain fusion proteins
Heather E. Moad et al.
PROTEIN SCIENCE (2013)
Endosomal proteolysis regulates calcitonin gene-related peptide responses in mesenteric arteries
A. J. McNeish et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Consequences of splice variation on Secretin family G protein-coupled receptor function
Sebastian G. B. Furness et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Pharmacological characterization of rat amylin receptors: implications for the identification of amylin receptor subtypes
R. J. Bailey et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine
Eric L. Moore et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Migraine is not primarily a vascular disorder
Andrew Charles
CEPHALALGIA (2012)
Vascular changes have a primary role in migraine
Messoud Ashina
CEPHALALGIA (2012)
Primary trigeminal afferents are the main source for stimulus-induced CGRP release into jugular vein blood and CSF
Jan Hoffmann et al.
CEPHALALGIA (2012)
Brainstem Neuropeptides and Vagal Protection of the Gastric Mucosal Against Injury: Role of Prostaglandins, Nitric Oxide and Calcitonin-Gene Related Peptide in Capsaicin Afferents
Y. Tache
CURRENT MEDICINAL CHEMISTRY (2012)
Opposite effects of substance P and calcitonin gene-related peptide in oxazolone colitis
Matthias A. Engel et al.
DIGESTIVE AND LIVER DISEASE (2012)
Amylin is a novel neuropeptide with potential maternal functions in the rat
Eva Rebeka Szabo et al.
FASEB JOURNAL (2012)
Direct optic nerve pulvinar connections defined by diffusion MR tractography in humans: Implications for photophobia
Nasim Maleki et al.
HUMAN BRAIN MAPPING (2012)
Calcitonin gene-related peptide enhances experimental autoimmune encephalomyelitis by promoting Th17-cell functions
Norihisa Mikami et al.
INTERNATIONAL IMMUNOLOGY (2012)
Sensitization of the Trigeminovascular Pathway: Perspective and Implications to Migraine Pathophysiology
Carolyn Bernstein et al.
JOURNAL OF CLINICAL NEUROLOGY (2012)
The proximodistal aggravation of colitis depends on substance P released from TRPV1-expressing sensory neurons
Matthias A. Engel et al.
JOURNAL OF GASTROENTEROLOGY (2012)
Brain-derived neurotrophic factor in primary headaches
Marlene Fischer et al.
JOURNAL OF HEADACHE AND PAIN (2012)
Modulation of CGRP-Induced Light Aversion in Wild-Type Mice by a 5-HT1B/D Agonist
Eric A. Kaiser et al.
JOURNAL OF NEUROSCIENCE (2012)
Neuropeptide Transmission in Brain Circuits
Anthony N. van den Pol
NEURON (2012)
The role of glutamic acid 73 in adrenomedullin interactions with rodent AM2 receptors
Angela Halim et al.
PEPTIDES (2012)
Critical role of calcitonin gene-related peptide receptors in cortical spreading depression
Alessandro Tozzi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Brain-derived neurotrophic factor enhances the contraction of intestinal muscle strips induced by SP and CGRP in mice
Fei-xue Chen et al.
REGULATORY PEPTIDES (2012)
Adrenomedullin and pregnancy: perspectives from animal models to humans
Patricia M. Lenhart et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)
Effects of estrogen on the serotonergic system and calcitonin generelated peptide in trigeminal ganglia of rats
Milan Aggarwal et al.
ANNALS OF NEUROSCIENCES (2012)
The Vascular Theory of Migraine: Leave It Or Love It?
Dan Levy et al.
ANNALS OF NEUROLOGY (2011)
Evidence for a Vascular Factor in Migraine
Mohammad S. Asghar et al.
ANNALS OF NEUROLOGY (2011)
Activation of Central Trigeminovascular Neurons by Cortical Spreading Depression
XiChun Zhang et al.
ANNALS OF NEUROLOGY (2011)
Dual-Specificity MAP Kinase Phosphatases as Targets of Cancer Treatment
Caroline Nunes-Xavier et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2011)
Calcitonin gene-related peptide (CGRP) and its receptor components in human and rat spinal trigeminal nucleus and spinal cord at C1-level
Sajedeh Eftekhari et al.
BMC NEUROSCIENCE (2011)
Cortical spreading depression affects reactive oxygen species production
Alessandro Viggiano et al.
BRAIN RESEARCH (2011)
Role of different brain areas in peripheral nerve injury-induced neuropathic pain
Amteshwar Singh Jaggi et al.
BRAIN RESEARCH (2011)
Organ culture of the trigeminal ganglion induces enhanced expression of calcitonin gene-related peptide via activation of extracellular signal-regulated protein kinase 1/2
Janos Tajti et al.
CEPHALALGIA (2011)
Increase in CGRP- and nNOS-immunoreactive neurons in the rat trigeminal ganglion after infusion of an NO donor
Anne Dieterle et al.
CEPHALALGIA (2011)
Epigenetic regulation of the calcitonin gene-related peptide gene in trigeminal glia
Ki-Youb Park et al.
CEPHALALGIA (2011)
Possible site of action of CGRP antagonists in migraine
Peer Tfelt-Hansen et al.
CEPHALALGIA (2011)
Pramlintide and the treatment of diabetes: a review of the data since its introduction
Lisa M. Younk et al.
EXPERT OPINION ON PHARMACOTHERAPY (2011)
Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation
Ann C. Raddant et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2011)
Sex Differences in Behavior and Expression of CGRP-Related Genes in a Rodent Model of Chronic Migraine
Nicholas L. Stucky et al.
HEADACHE (2011)
Calcitonin Gene-Related Peptide Does Not Cause Migraine Attacks in Patients With Familial Hemiplegic Migraine
Jakob M. Hansen et al.
HEADACHE (2011)
Role of Sensory Neurons in Colitis: Increasing Evidence for a Neuroimmune Link in the Gut
Matthias A. Engel et al.
INFLAMMATORY BOWEL DISEASES (2011)
Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes
Katharina Timper et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
CGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice
Weiliang Xie et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Neurovascular Aspects of Skin Neurogenic Inflammation
Aisah A. Aubdool et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS (2011)
Calcitonin Gene-Related Peptide in the Bed Nucleus of the Stria Terminalis Produces an Anxiety-Like Pattern of Behavior and Increases Neural Activation in Anxiety-Related Structures
Kelly S. Sink et al.
JOURNAL OF NEUROSCIENCE (2011)
Calcitonin Gene-Related Peptide-Mediated Enhancement of Purinergic Neuron/Glia Communication by the Algogenic Factor Bradykinin in Mouse Trigeminal Ganglia from Wild-Type and R192Q Cav2.1 Knock-In Mice: Implications for Basic Mechanisms of Migraine Pain
Stefania Ceruti et al.
JOURNAL OF NEUROSCIENCE (2011)
Cerebellar distribution of calcitonin gene-related peptide (CGRP) and its receptor components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) in rat
Lars Edvinsson et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2011)
Calcitonin Gene-Related Peptide Promotes Cellular Changes in Trigeminal Neurons and Glia Implicated in Peripheral and Central Sensitization
Ryan J. Cady et al.
MOLECULAR PAIN (2011)
CGRP Sensory neuropeptide with multiple neurologic implications
Eduardo E. Benarroch
NEUROLOGY (2011)
Calcitonin gene-related peptide (CGRP) and its role in hypertension
Sarah-Jane Smillie et al.
NEUROPEPTIDES (2011)
Keratinocyte expression of calcitonin gene-related peptide β: Implications for neuropathic and inflammatory pain mechanisms
Quanzhi Hou et al.
PAIN (2011)
Thalamic Sensitization Transforms Localized Pain into Widespread Allodynia
Rami Burstein et al.
ANNALS OF NEUROLOGY (2010)
Calcitonin gene-related peptide inhibits angiotensin II-induced endothelial progenitor cells senescence through up-regulation of klotho expression
Zhi Zhou et al.
ATHEROSCLEROSIS (2010)
Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74
Philip S. Miller et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Modulation of nocioceptive transmission with calcitonin gene-related peptide receptor antagonists in the thalamus
Oliver Summ et al.
BRAIN (2010)
Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura
Jakob Moller Hansen et al.
CEPHALALGIA (2010)
Dopamine: what's new in migraine?
Annabelle R. Charbit et al.
CURRENT OPINION IN NEUROLOGY (2010)
An update on the blood vessel in migraine
K. C. Brennan et al.
CURRENT OPINION IN NEUROLOGY (2010)
What have we learnt from triggering migraine?
Henrik W. Schytz et al.
CURRENT OPINION IN NEUROLOGY (2010)
Mice Lacking the Neuropeptide α-Calcitonin Gene-Related Peptide Are Protected Against Diet-Induced Obesity
Christopher S. Walker et al.
ENDOCRINOLOGY (2010)
Mitogen-activated protein kinase phosphatase-1-a potential therapeutic target in metabolic disease
Rachel J. Roth Flach et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2010)
Migraine Pain and Nociceptor Activation-Where Do We Stand?
Dan Levy
HEADACHE (2010)
Verisimilitude (or truthlikeness) as an alternative to pro and cons: migraine and cluster headache mechanisms
Peer Carsten Tfelt-Hansen
JOURNAL OF HEADACHE AND PAIN (2010)
Activation of Meningeal Nociceptors by Cortical Spreading Depression: Implications for Migraine with Aura
XiChun Zhang et al.
JOURNAL OF NEUROSCIENCE (2010)
Pharmacological Properties of MK-3207, a Potent and Orally Active Calcitonin Gene-Related Peptide Receptor Antagonist
Christopher A. Salvatore et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Facilitation of synaptic transmission and pain responses by CGRP in the amygdala of normal rats
Jeong S. Han et al.
MOLECULAR PAIN (2010)
A neural mechanism for exacerbation of headache by light
Rodrigo Noseda et al.
NATURE NEUROSCIENCE (2010)
CGRP and its receptors provide new insights into migraine pathophysiology
Tony W. Ho et al.
NATURE REVIEWS NEUROLOGY (2010)
Induction of multiple photophobic behaviors in a transgenic mouse sensitized to CGRP
Ana Recober et al.
NEUROPHARMACOLOGY (2010)
AMYLIN SUPPRESSES ACETIC ACID-INDUCED VISCERAL PAIN AND SPINAL C-FOS EXPRESSION IN THE MOUSE
X. Huang et al.
NEUROSCIENCE (2010)
DIFFERENTIAL DISTRIBUTION OF CALCITONIN GENE-RELATED PEPTIDE AND ITS RECEPTOR COMPONENTS IN THE HUMAN TRIGEMINAL GANGLION
S. Eftekhari et al.
NEUROSCIENCE (2010)
Calcitonin gene-related peptide differentially regulates gene and protein expression in trigeminal glia cells: Findings from array analysis
Carrie V. Vause et al.
NEUROSCIENCE LETTERS (2010)
Triptan Therapy in Migraine
Elizabeth Loder
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Calcitonin gene-related peptide regulates the growth of epidermal stem cells in vitro
Jie Dong et al.
PEPTIDES (2010)
Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism
Ernst ter Haar et al.
STRUCTURE (2010)
Regulation of signal transduction by calcitonin gene-related peptide receptors
Christopher S. Walker et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2010)
Neuropeptides in the rat corpus cavernosum and seminal vesicle: Effects of age and two types of diabetes
J. F. B. Morrison et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2009)
PACAP38 induces migraine-like attacks in patients with migraine without aura
Henrik Winther Schytz et al.
BRAIN (2009)
The vascular theory of migrainea great story wrecked by the facts
Peter J. Goadsby
BRAIN (2009)
Brainstem and thalamic projections from a craniovascular sensory nervous centre in the rostral cervical spinal dorsal horn of rats
Y. Liu et al.
CEPHALALGIA (2009)
Role of Calcitonin Gene-Related Peptide in Gastric Mucosal Defence and Healing
S. Evangelista
CURRENT PHARMACEUTICAL DESIGN (2009)
Examining the binding properties of MK-0974: A CGRP receptor antagonist for the acute treatment of migraine
Eric L. Moore et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Involvement of afferent neurons in the pathogenesis of endotoxin-induced ileus in mice: Role of CGRP and TRPV1 receptors
Benedicte Y. De Winter et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Elevated Saliva Calcitonin Gene-Related Peptide Levels During Acute Migraine Predict Therapeutic Response to Rizatriptan
Roger K. Cady et al.
HEADACHE (2009)
Role of calcitonin gene-related peptide (CGRP) in ovine burn and smoke inhalation injury
Matthias Lange et al.
JOURNAL OF APPLIED PHYSIOLOGY (2009)
Sensory Innervation of the Calvarial Bones of the Mouse
Bela Kosaras et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2009)
Plasma calcitonin gene-related peptide concentration is comparable to control group among migraineurs and tension type headache subjects during inter-ictal period
Ravi Gupta et al.
JOURNAL OF HEADACHE AND PAIN (2009)
Calcitonin gene-related peptide in blood: is it increased in the external jugular vein during migraine and cluster headache? A review
Peer Tfelt-Hansen et al.
JOURNAL OF HEADACHE AND PAIN (2009)
Central amylin expression and its induction in rat dams
Arpad Dobolyi
JOURNAL OF NEUROCHEMISTRY (2009)
Neurons of the Dopaminergic/Calcitonin Gene-Related Peptide A11 Cell Group Modulate Neuronal Firing in the Trigeminocervical Complex: An Electrophysiological and Immunohistochemical Study
Annabelle R. Charbit et al.
JOURNAL OF NEUROSCIENCE (2009)
Genetic Enhancement of Calcitonin Gene-Related Peptide-Induced Central Sensitization to Mechanical Stimuli in Mice
Blanca Marquez de Prado et al.
JOURNAL OF PAIN (2009)
Origin of pain in migraine: evidence for peripheral sensitisation
Jes Olesen et al.
LANCET NEUROLOGY (2009)
Proinflammatory-activated trigeminal satellite cells promote neuronal sensitization: relevance for migraine pathology
Alessandro Capuano et al.
MOLECULAR PAIN (2009)
Calcitonin gene-related peptide, adrenomedullin and flushing
Debbie L. Hay et al.
MATURITAS (2009)
Neural substrate of depression during migraine
Rami Burstein et al.
NEUROLOGICAL SCIENCES (2009)
The role of CGRP in the pathophysiology of migraine and efficacy of CGRP receptor antagonists as acute antimigraine drugs
Carlos M. Villalon et al.
PHARMACOLOGY & THERAPEUTICS (2009)
A role for the medial preoptic area in CGRP-induced suppression of pulsatile LH secretion in the female rat
X. F. Li et al.
STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS (2009)
Migraine: where and how does the pain originate?
Karl Messlinger
EXPERIMENTAL BRAIN RESEARCH (2009)
Proteases for processing proneuropeptides into peptide neurotransmitters and hormones
Vivian Hook et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2008)
Central projections of the sensory innervation of the rat middle meningeal artery
Yi Liu et al.
BRAIN RESEARCH (2008)
CGRP blockers in migraine therapy: where do they act?
L. Edvinsson
BRITISH JOURNAL OF PHARMACOLOGY (2008)
The blood-brain barrier in migraine treatment
L. Edvinsson et al.
CEPHALALGIA (2008)
Comparison of CGRP and NO responses in the human peripheral microcirculation of migraine and control subjects
M-L Edvinsson et al.
CEPHALALGIA (2008)
Procalcitonin has bioactivity at calcitonin receptor family complexes: Potential mediator implications in sepsis
Patrick M. Sexton et al.
CRITICAL CARE MEDICINE (2008)
Receptor Activity-Modifying Proteins Differentially Modulate the G Protein-Coupling Efficiency of Amylin Receptors
Maria Morfis et al.
ENDOCRINOLOGY (2008)
Evidence that alpha-calcitonin gene-related peptide is a neurohormone that controls systemic lipid availability and utilization
Rachel N. Danaher et al.
ENDOCRINOLOGY (2008)
Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis
Takashi Ohno et al.
GASTROENTEROLOGY (2008)
Mechanisms mediating the enhanced gene transcription of P2X3 receptor by calcitonin gene-related peptide in trigeminal sensory neurons
Manuela Simonetti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactlivity in the rat trigeminovascular system:: Differences between peripheral and central CGRP receptor distribution
Jochen K. Lennerz et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2008)
The hemo-neural hypothesis: On the role of blood flow in information processing
Christopher I. Moore et al.
JOURNAL OF NEUROPHYSIOLOGY (2008)
Repression of prespliceosome complex formation at two distinct steps by Fox-1/Fox-2 proteins
Hua-Lin Zhou et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Molecular mechanisms of sensitization of pain-transducing P2X3 receptors by the migraine mediators CGRP and NGF
Rashid Giniatullin et al.
MOLECULAR NEUROBIOLOGY (2008)
Calcitonin gene-related peptide does not cause the familial hemiplegic migraine phenotype
Jakob Moller Hansen et al.
NEUROLOGY (2008)
International Union of Pharmacology. LXIX. Status of the calcitonin gene-related peptide subtype 2 receptor
Debbie L. Hay et al.
PHARMACOLOGICAL REVIEWS (2008)
The effects of C-terminal truncation of receptor activity modifying proteins on the induction of amylin receptor phenotype from human CTb receptors
Madhara Udawela et al.
REGULATORY PEPTIDES (2008)
Control of the calcitonin gene-related peptide enhancer by upstream stimulatory factor in trigeminal ganglion neurons
Ki-Youb Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Pharmacological characterization of MK-0974 [N-[(3R, 6S)-6(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b] pyridin-1-yl)piperidine-1-carboxamide], a potent and orally Active calcitonin gene-related peptide receptor antagonist for the treatment of migraine
Christopher A. Salvatore et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Protective roles of alpha-calcitonin and beta-calcitonin gene-related peptide in spontaneous and experimentally induced colitis
Brent J. Thompson et al.
DIGESTIVE DISEASES AND SCIENCES (2008)
Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and β-arrestins
Benjamin E. Padilla et al.
JOURNAL OF CELL BIOLOGY (2007)
Role of visceral afferent neurons in mucosal inflammation and defense
Peter Holzer
CURRENT OPINION IN PHARMACOLOGY (2007)
Calcitonin gene-related peptide mediates acid-induced lung injury in mice
Tomoko Aoki-Nagase et al.
RESPIROLOGY (2007)
What makes a CGRP2 receptor?
D. L. Hay
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2007)
Interactions between olfaction and the trigeminal system: What can be learned from olfactory loss
Johannes Frasnelli et al.
CEREBRAL CORTEX (2007)
Calcitonin receptor-like and receptor activity modifying protein 1 in the rat dorsal horn localization in glutamatergic presynaptic terminal containing opioids and adrenergic α2c receptor
J. C. G. Marvizon et al.
NEUROSCIENCE (2007)
Calcitonin gene-related peptide induces the expression of acetylcholinesterase-associated collagen ColQ in muscle: a distinction in driving two different promoters between fast- and slow-twitch muscle fibers
Roy C. Y. Choi et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Neuron-glia signaling in trigeminal ganglion: Implications for migraine pathology
Srikanth Thalakoti et al.
HEADACHE (2007)
Role of calcitonin receptor-like receptor in colonic motility and inflammation
Matthew S. Clifton et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age
Ryan Dackor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Modification of classical neurochemical markers in identified primary afferent neurons with Aβ-, Aδ-, and C-fibers after chronic constriction injury in mice
Ruth Ruscheweyh et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2007)
Pharmacological approaches to managing migraine and associated comorbidities - Clinical considerations for monotherapy versus polytherapy
Stephen D. Silberstein et al.
HEADACHE (2007)
Involvement of endothelial cell-derived CGRP in heat stress-induced protection of endothelial function
Feng Ye et al.
VASCULAR PHARMACOLOGY (2007)
The colocalization of CGRP receptor and AMPA receptor in the spinal dorsal horn neuron of rat: A morphological and electrophysiological study
Xing-Long Gu et al.
NEUROSCIENCE LETTERS (2007)
Sensitization of calcitonin gene-related peptide receptors by receptor activity-modifying protein-1 in the trigeminal ganglion
Zhongming Zhang et al.
JOURNAL OF NEUROSCIENCE (2007)
Role for Fox-1/Fox-2 in mediating the neuronal pathway of calcitonin/calcitonin gene-related peptide alternative RNA processing
Hua-Lin Zhou et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
A nuclear function of Hu proteins as neuron-specific alternative RNA processing regulators
Hui Zhu et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Determinants of 1-piperidinecarboxamide, N-[2-[[5-amino-l-[[4(4-pyridinyl)-l-piperazinyl]carbonyl]pentyl]amino]-1-[(3,5-dibromo-4-hydroxyphenyl)methyl]-2-oxoethyl]-4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl) (BIBN4096BS) affinity for calcitonin gene-related peptide and amylin receptors -: The role of receptor activity modifying protein 1
Debbie L. Hay et al.
MOLECULAR PHARMACOLOGY (2006)
A critical role for the short intracellular C terminus in receptor activity-modifying protein function
Madhara Udawela et al.
MOLECULAR PHARMACOLOGY (2006)
Pharmacological characterization of novel α-calcitonin gene-related peptide (CGRP) receptor peptide antagonists that are selective for human CGRP receptors
Christopher K. Taylor et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Delayed upregulation of ATP P2X3 receptors of trigeminal sensory neurons by calcitonin gene-related peptide
Elsa Fabbretti et al.
JOURNAL OF NEUROSCIENCE (2006)
Pharmacology of the human CGRP1 receptor in Cos 7 cells
Richard J. Bailey et al.
PEPTIDES (2006)
Calcitonin gene-related peptide receptor activation by receptor activity-modifying protein-1 gene transfer to vascular smooth muscle cells
ZM Zhang et al.
ENDOCRINOLOGY (2006)
Nitric oxide regulation of calcitonin gene-related peptide gene expression in rat trigeminal ganglia neurons
J Bellamy et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the Calcitonin receptor-like receptor gene
RT Dackor et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Dendritic peptide release and peptide-dependent behaviours
M Ludwig et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Immunocytochemical localization of adrenomedullin 2/intermedin-like immunoreactivity in human hypothalamus, heart and kidney
Kazuhiro Takahashi et al.
PEPTIDES (2006)
Adventitial neuronal somata
Chandra Somasundaram et al.
JOURNAL OF VASCULAR RESEARCH (2006)
Tumor necrosis factor-alpha stimulation of calcitonin gene-related peptide expression and secretion from rat trigeminal ganglion neurons
EJ Bowen et al.
JOURNAL OF NEUROCHEMISTRY (2006)
GPCR modulation by RAMPS
DL Hay et al.
PHARMACOLOGY & THERAPEUTICS (2006)
Salivary levels of CGRP and VIP in rhinosinusitis and migraine patients
JL Bellamy et al.
HEADACHE (2006)
Endogenous NGF regulates CGRP expression in human monocytes, and affects HLA-DR and CD86 expression and IL-10 production
L Bracci-Laudiero et al.
BLOOD (2005)
No increase of calcitonin gene-related peptide in jugular blood during migraine
JF Tvedskov et al.
ANNALS OF NEUROLOGY (2005)
Without nerves, immunology remains incomplete -: in vivo veritas
AJ Shepherd et al.
IMMUNOLOGY (2005)
Localization of calcitonin receptor-like receptor and receptor activity modifying protein 1 in enteric neurons, dorsal root ganglia, and the spinal cord of the rat
GS Cottrell et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2005)
The nonpeptide calcitonin gene-related peptide receptor antagonist BIBN4096BS lowers the activity of neurons with meningeal input in the rat spinal trigeminal nucleus
MJM Fischer et al.
JOURNAL OF NEUROSCIENCE (2005)
Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue
P Linscheid et al.
ENDOCRINOLOGY (2005)
Endogenous calcitonin gene-related peptide protects human alveolar epithelial cells through protein kinase Cε and heat shock protein
W Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Impaired capsaicin and neurokinin-evoked colonic motility in inflammatory bowel disease
AS Smith et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2005)
Pharmacological discrimination of calcitonin receptor: receptor activity-modifying protein complexes
DL Hay et al.
MOLECULAR PHARMACOLOGY (2005)
Evidence for decreased calcitonin gene-related peptide (CGRP) receptors and compromised responsiveness to CGRP of fetoplacental vessels in preeclamptic pregnancies
YL Dong et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
BIBN4096BS antagonizes human α-calcitonin gene related peptide-induced headache and extracerebral artery dilatation
KA Petersen et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2005)
Sumatriptan causes parallel decrease in plasma calcitonin gene-related peptide (CGRP) concentration and migraine headache during nitroglycerin induced migraine attack
G Juhasz et al.
CEPHALALGIA (2005)
Can we develop neurally acting drugs for the treatment of migraine?
PJ Goadsby
NATURE REVIEWS DRUG DISCOVERY (2005)
Ca2+ and frequency dependence of exocytosis in isolated somata of magnocellular supraoptic neurones of the rat hypothalamus
BL Soldo et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Calcitonin gene-related peptide receptor antagonist BIBN4096BS for the acute treatment of migraine
J Olesen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes
J Roh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Peripheral amylin activates circumventricular organs expressing calcitonin receptor a/b subtypes and receptor-activity modifying proteins in the rat
SW Barth et al.
BRAIN RESEARCH (2004)
Neuronal expression and regulation of CGRP promoter activity following viral gene transfer into cultured trigeminal ganglia neurons
PL Durham et al.
BRAIN RESEARCH (2004)
Identification of novel adrenomedullin in mammals: a potent cardiovascular and renal regulator
Y Takei et al.
FEBS LETTERS (2004)
Effect of pramlintide on symptom, catecholamine, and glucagon responses to hypoglycemia in healthy subjects
T Heise et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2004)
Analysis of the cellular expression pattern of β-CGRP in α-CGRP-deficient mice
B Schütz et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2004)
Calcitonin gene-related peptide (CGRP) modulates nociceptive trigeminovascular transmission in the cat
RJ Storer et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Both U2 snRNA and U12 snRNA are required for accurate splicing of exon 5 of the rat calcitonin/CGRP gene
JR Roesser
RNA (2004)
Immunohistochemical mapping of calcitonin receptors in the adult rat brain
C Becskei et al.
BRAIN RESEARCH (2004)
Vascular actions of calcitonin gene-related peptide and adrenomedullin
SD Brain et al.
PHYSIOLOGICAL REVIEWS (2004)
Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues
V Besnard et al.
GENE EXPRESSION PATTERNS (2004)
Calcitonin gene-related peptide regulates gene transcription in primary afferent neurons
LE Anderson et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Long-term induction of β-CGRP mRNA in rat lungs by allergic inflammation
J Tsukiji et al.
LIFE SCIENCES (2004)
Regulation of the cell-specific calcitonin/calcitonin gene-related peptide enhancer by USF and the Foxa2 forkhead protein
TJ Viney et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Central projections of sensory innervation of the rat superior sagittal sinus
Y Liu et al.
NEUROSCIENCE (2004)
Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization
RQ Sun et al.
JOURNAL OF NEUROPHYSIOLOGY (2004)
The amygdala and persistent pain
V Neugebauer et al.
NEUROSCIENTIST (2004)
Expression of calcitonin gene-related peptide type 1 receptor mRNA and their activity-modifying proteins in the rat nucleus accumbens
N Li et al.
NEUROSCIENCE LETTERS (2004)
Effects of alpha calcitonin gene-related peptide in human bronchial smooth muscle and pulmonary artery
J Springer et al.
REGULATORY PEPTIDES (2004)
Three receptor-activity-modifying proteins define calcitonin gene-related peptide or adrenomedullin selectivity of the mouse calcitonin-like receptor in COS-7 cells
K Husmann et al.
BIOCHEMICAL PHARMACOLOGY (2003)
CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors:: a comparison of effects of adrenomedullin22-52, CGRP8-37 and BIBN4096BS
DL Hay et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Mechanism of interleukin-1β-induced calcitonin gene-related peptide production from dorsal root ganglion neurons of neonatal rats
LF Hou et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2003)
Glutamate and nitric oxide pathway in chronic daily headache: evidence from cerebrospinal fluid
V Gallai et al.
CEPHALALGIA (2003)
Paraventricular nucleus administration of calcitonin gene-related peptide inhibits food intake and stimulates the hypothalamo-pituitary-adrenal axis
WS Dhillo et al.
ENDOCRINOLOGY (2003)
SRp55 is a regulator of calcitonin/CGRP alternative RNA splicing
Q Tran et al.
BIOCHEMISTRY (2003)
Ontogeny of calcitonin receptor mRNA and protein in the developing central nervous system of the rat
M Tolcos et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2003)
Loss of alpha CGRP reduces sound-evoked activity in the cochlear nerve
SF Maison et al.
JOURNAL OF NEUROPHYSIOLOGY (2003)
Mechanisms involved in calcitonin gene-related peptide-induced relaxation in pregnant rat uterine artery
PRR Gangula et al.
BIOLOGY OF REPRODUCTION (2003)
Calcitonin gene-related peptide as inflammatory mediator
J Springer et al.
PULMONARY PHARMACOLOGY & THERAPEUTICS (2003)
Expression and regulation of calcitonin gene-related peptide receptor in rat placentas
YL Dong et al.
BIOLOGY OF REPRODUCTION (2002)
A comparison of the actions of BIBN4096BS and CGRP8-37 on CGRP and adrenomedullin receptors expressed on SK-N-MC, L6, Col 29 and Rat 2 cells
DL Hay et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
Infusion of pregnant rats with calcitonin gene-related peptide (CGRP)8-37, a CGRP receptor antagonist, increases blood pressure and fetal mortality and decreases fetal growth
PRR Gangula et al.
BIOLOGY OF REPRODUCTION (2002)
An immunocytochemical investigation of human trigeminal nucleus caudalis:: CGRP, substance P and 5-HT1D-receptor immunoreactivities are expressed by trigeminal sensory fibres
D Smith et al.
CEPHALALGIA (2002)
Comparison of the expression of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) with CGRP and adrenomedullin binding in cell lines
T Choksi et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors
DR Poyner et al.
PHARMACOLOGICAL REVIEWS (2002)
Adenosine A1 receptor agonists inhibit trigeminovascular nociceptive transmission
PJ Goadsby et al.
BRAIN (2002)
Localization of calcitonin gene-related peptide receptors in rat gastric mucosa
K Kawashima et al.
PEPTIDES (2002)
Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists
JJ Mallee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
New insights into the molecular actions of serotonergic antimigraine drugs
PL Durham et al.
PHARMACOLOGY & THERAPEUTICS (2002)
Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model
H Bolay et al.
NATURE MEDICINE (2002)
CGRP may play a causative role in migraine
LH Lassen et al.
CEPHALALGIA (2002)
Drug therapy: Migraine - Current understanding and treatment.
PJ Goadsby et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Neuropeptide expression in the human trigeminal nucleus caudalis and in the cervical spinal cord C1 and C2
R Uddman et al.
CEPHALALGIA (2002)
Expression of receptor-activity modifying protein (RAMP) mRNAs in the mouse brain
T Ueda et al.
MOLECULAR BRAIN RESEARCH (2001)
The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression
MD Galibert et al.
EMBO JOURNAL (2001)
Cloning, characterization and distribution of receptor activity central nervous system modifying proteins in the rat
KR Oliver et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
Levels of nerve growth factor in cerebrospinal fluid of chronic daily headache patients
P Sarchielli et al.
NEUROLOGY (2001)
Prevalence and burden of migraine in the United States: Data from the American Migraine Study II
RB Lipton et al.
HEADACHE (2001)
Adjuvant-induced joint inflammation causes very rapid transcription of β-preprotachykinin and α-CGRP genes in innervating sensory ganglia
DGS Bulling et al.
JOURNAL OF NEUROCHEMISTRY (2001)
The expression of calcitonin gene-related peptide in dorsal horn neurons of the mouse lumbar spinal cord
SS Tie-Jun et al.
NEUROREPORT (2001)
Pharmacological evidence for CGRP uptake into perivascular capsaicin sensitive nerve terminals
A Sams-Nielsen et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
Capsaicin-sensitive afferents and their role in gastroprotection: an update
J Szolcsanyi et al.
JOURNAL OF PHYSIOLOGY-PARIS (2001)
Nitric oxide metabolites, prostaglandins and trigeminal vasoactive peptides in internal jugular vein blood during spontaneous migraine attacks
P Sarchielli et al.
CEPHALALGIA (2000)
Release of calcitonin gene-related peptide (CGRP) from guinea pig dura mater in vitro is inhibited by sumatriptan but unaffected by nitric oxide
CT Eltorp et al.
CEPHALALGIA (2000)
Immunohistochemical localization of amylin in rat brainstem
L D'Este et al.
PEPTIDES (2000)
Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors
V Souslova et al.
NATURE (2000)
Induction and expression of β-calcitonin gene-related peptide in rat T lymphocytes and its significance
LY Xing et al.
JOURNAL OF IMMUNOLOGY (2000)
Vascular matrix metalloproteinase-2-dependent cleavage of calcitonin gene-related peptide promotes vasoconstriction
C Fernandez-Patron et al.
CIRCULATION RESEARCH (2000)
CGRP-RCP, a novel protein required for signal transduction at calcitonin gene-related peptide and adrenomedullin receptors
BN Evans et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Anti-nociceptive effects of calcitonin gene-related peptide in nucleus raphe magnus of rats: an effect attenuated by naloxone
YH Huang et al.
BRAIN RESEARCH (2000)
Cellular localization of neprilysin in mouse bone tissue and putative role in hydrolysis of osteogenic peptides
AF Ruchon et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2000)
CGRP2 receptor in the internal anal sphincter of the rat:: implications for CGRP receptor classification
FM Wisskirchen et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Localization of calcitonin receptor mRNA in the mouse brain: coexistence with serotonin transporter mRNA
H Nakamoto et al.
MOLECULAR BRAIN RESEARCH (2000)
In vivo gene transfer of prepro-calcitonin gene-related peptide to the lung attenuates chronic hypoxia-induced pulmonary hypertension in the mouse
HC Champion et al.
CIRCULATION (2000)
CGRP and adrenomedullin binding correlates with transcript levels for Calcitonin Receptor-Like Receptor (CRLR) and Receptor Activity Modifying Proteins (RAMPs) in rat tissues
P Chakravarty et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist
H Doods et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Calcitonin gene-related peptide-like immunoreactivity marks putative visceral sensory pathways in human brain
S De Lacalle et al.
NEUROSCIENCE (2000)
Digestive motor effects and vascular actions of CGRP in dog are expressed by different receptor subtypes
MC L'Heureux et al.
PEPTIDES (2000)