4.6 Article

Modeling families of particle distributions with conditional GAN for Monte Carlo SPECT simulations

Journal

PHYSICS IN MEDICINE AND BIOLOGY
Volume 67, Issue 23, Pages -

Publisher

IOP Publishing Ltd
DOI: 10.1088/1361-6560/aca068

Keywords

conditional GAN; wasserstein; Monte Carlo; SPECT simulation

Funding

  1. MOCAMED project [ANR-20-CE45-0025]
  2. SIRIC LYriCAN Grant [INCa-INSERM-DGOS-12563]
  3. LABEX PRIMES of Universite de Lyon, within the program Investissements d'Avenir' [ANR-11-LABX-0063, ANR-19-PERM-0007-04]
  4. HPC resources of IDRIS
  5. Agence Nationale de la Recherche (ANR) [ANR-19-PERM-0007] Funding Source: Agence Nationale de la Recherche (ANR)

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In this study, a method to model families of particle distributions exiting a phantom in single photon emission computed tomography imaging devices using a condGAN is proposed. The condGAN is trained on a low statistics dataset and can generate particles with specific energy and position, leading to improved computational efficiency.
Objective. We propose a method to model families of distributions of particles exiting a phantom with a conditional generative adversarial network (condGAN) during Monte Carlo simulation of single photon emission computed tomography imaging devices. Approach. The proposed condGAN is trained on a low statistics dataset containing the energy, the time, the position and the direction of exiting particles. In addition, it also contains a vector of conditions composed of four dimensions: the initial energy and the position of emitted particles within the phantom (a total of 12 dimensions). The information related to the gammas absorbed within the phantom is also added in the dataset. At the end of the training process, one component of the condGAN, the generator (G), is obtained. Main results. Particles with specific energies and positions of emission within the phantom can then be generated with G to replace the tracking of particle within the phantom, allowing reduced computation time compared to conventional Monte Carlo simulation. Significance. The condGAN generator is trained only once for a given phantom but can generate particles from various activity source distributions.

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