Safety Evaluation of Far-UV-C Irradiation to Epithelial Basal Cells in the Corneal Limbus

Review Dermatology

TGFβ Signaling in Photoaging and UV-Induced Skin Cancer

Yao Ke et al.

Summary: UVR-induced TGF-beta signaling activation and gene mutations play significant roles in photoaging and the development of skin cancer.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2021)

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Review Ophthalmology

Corneal stromal mesenchymal stem cells: reconstructing a bioactive cornea and repairing the corneal limbus and stromal microenvironment

Xian-Ning Liu et al.

Summary: CS-MSCs, derived from the corneal stroma, have self-renewal and multidirectional differentiation potential, which can be induced to differentiate into functional keratocytes in vitro. They play a crucial role in maintaining corneal transparency and reconstructing ocular surface tissue. Moreover, they have great application prospects in tissue engineering for active biocornea construction.

INTERNATIONAL JOURNAL OF OPHTHALMOLOGY (2021)

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Article Biochemistry & Molecular Biology

Re-Evaluation of Rat Corneal Damage by Short-Wavelength UV Revealed Extremely Less Hazardous Property of Far-UV-C†

Sachiko Kaidzu et al.

Summary: Short-wavelength UV-C (207 and 222 nm) is less hazardous to the cornea compared to longer UV wavelengths, as this radiation only penetrates to the outermost layer of the corneal epithelium, where the cells typically peel off within 24 hours. Therefore, short-wavelength UV-C may be less harmful to the cornea than previously thought.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2021)

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Article Biochemistry & Molecular Biology