Journal
PATHOLOGY RESEARCH AND PRACTICE
Volume 242, Issue -, Pages -Publisher
ELSEVIER GMBH
DOI: 10.1016/j.prp.2023.154316
Keywords
Bladder cancer (BC); Pathogenesis; Oncogenic miRNAs; Tumor suppressor (TS) miRNAs; Biogenesis
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Bladder cancer is the 11th most popular cancer in females and 4th in males. Efforts have been made to improve BC patients' care, and new approaches have been developed to enhance the efficiency of BC diagnosis, prognosis, therapeutics, and monitoring.
Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of efforts have been exerted to improve BC patients' care. Besides, new approaches have been developed to enhance the efficiency of BC diagnosis, prognosis, therapeutics, and monitoring. MicroRNAs (miRNAs, miRs) are small chain nucleic acids that can regulate wide networks of cellular events. They can inhibit or degrade their target protein-encoding genes. The miRNAs are either downregulated or upregulated in BC due to epigenetic alterations or biogenesis machinery abnormalities. In BC, dysregulation of miRNAs is associated with cell cycle arrest, apoptosis,
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