Journal
ORGANIC LETTERS
Volume 24, Issue 45, Pages 8326-8330Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.2c03325
Keywords
-
Categories
Funding
- NSF [CHE2102626, 1S10RR023444, CHE- 1827457, 3R01GM118510-03S1, 3R01GM087605-06S1]
- Vagelos Institute for Energy Science and Technology
- NIH
Ask authors/readers for more resources
A method to cleave the C-C biaryl bond of binaphthyl derivatives under reductive conditions is described. Monomeric products were obtained in improved yields by employing triflic acid together with a catalytic HAT reagent and catalytic Pd/C. Kinetic analyses provided insight into the mechanism of aryl-aryl activation.
A method to cleave the C-C biaryl bond of binaphthyl derivatives under reductive conditions is described. Triflic acid employed together with a catalytic HAT reagent, 2ethyl-9,10-dihydroxyanthracene, that is regenerated using H2 with catalytic Pd/C yielded monomeric products in improved yields. A range of substrates is disclosed, and kinetic analyses provide insight into the mechanism of aryl-aryl activation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available