Related references
Note: Only part of the references are listed.Design, synthesis, high algicidal potency, and putative mode of action of new 2-cyclopropyl-4-aminopyrimidine hydrazones
Yuan Zhou et al.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY (2022)
Frontiers in the enzymology of thiamin diphosphate-dependent enzymes
Sabin Prajapati et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2022)
Synthesis of pyrrothiamine, a novel thiamine analogue, and evaluation of derivatives as potent and selective inhibitors of pyruvate dehydrogenase
Alex H. Y. Chan et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2022)
Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening
Di Zhu et al.
CHEMICAL SCIENCE (2022)
Thiamine analogues as inhibitors of pyruvate dehydrogenase and discovery of a thiamine analogue with non-thiamine related antiplasmodial activity
Alex H. Y. Chan et al.
RSC MEDICINAL CHEMISTRY (2022)
Prodrugs of pyrophosphates and bisphosphonates: disguising phosphorus oxyanions
Emma S. Rudge et al.
RSC MEDICINAL CHEMISTRY (2022)
Discovery of efficient inhibitors against pyruvate dehydrogenase complex component E1 with bactericidal activity using computer aided design
Yuan Zhou et al.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY (2021)
Differences in the efficiency of 3-deazathiamine and oxythiamine pyrophosphates as inhibitors of pyruvate dehydrogenase complex and growth of HeLa cells in vitro
Ewa Grabowska et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2021)
Antibacterial activity and mechanism of ThDP analogs against rice brown stripe pathogen Acidovorax avenae subsp. avenae RS-1
Xiao Xuan Wang et al.
JOURNAL OF PLANT PATHOLOGY (2019)
Structure optimization and bioactivity evaluation of ThDP analogs targeting cyanobacterial pyruvate dehydrogenase E1
Jiangtao Feng et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2019)
Enamide Prodrugs of Acetyl Phosphonate Deoxy-D-xylulose-5-phosphate Synthase Inhibitors as Potent Antibacterial Agents
David Bartee et al.
ACS INFECTIOUS DISEASES (2019)
Targeting the Unique Mechanism of Bacterial 1-Deoxy-D-xylulose-5-phosphate Synthase
David Bartee et al.
BIOCHEMISTRY (2018)
Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer
Jingjing Chen et al.
NATURE GENETICS (2018)
Toward Understanding the Chemistry and Biology of 1-Deoxy-D-xylulose 5-Phosphate (DXP) Synthase: A Unique Antimicrobial Target at the Heart of Bacterial Metabolism
David Bartee et al.
ACCOUNTS OF CHEMICAL RESEARCH (2018)
Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism
Sungmi Park et al.
DIABETES & METABOLISM JOURNAL (2018)
Challenges and Hallmarks of Establishing Alkylacetylphosphonates as Probes of Bacterial 1-Deoxy-D-xylulose 5-Phosphate Synthase
Sara Sanders et al.
ACS INFECTIOUS DISEASES (2017)
Metabolic Heterogeneity in Human Lung Tumors
Christopher T. Hensley et al.
CELL (2016)
Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer
Shawn M. Davidson et al.
CELL METABOLISM (2016)
The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V. Liberti et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
Design and synthesis of thiamine analogues to study their binding to the ECF transporter for thiamine in bacteria
L. Monjas et al.
MEDCHEMCOMM (2016)
Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine
Lotteke J. Y. M. Swier et al.
CHEMBIOCHEM (2015)
Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS
T. Masini et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2015)
Gold(I)-catalysed synthesis of a furan analogue of thiamine pyrophosphate
Amjid Iqbal et al.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY (2014)
The role of ligand efficiency metrics in drug discovery
Andrew L. Hopkins et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Chemical and genetic validation of thiamine utilization as an antimalarial drug target
Xie Wah Audrey Chan et al.
NATURE COMMUNICATIONS (2013)
Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology
Gopinath Sutendra et al.
FRONTIERS IN ONCOLOGY (2013)
Thiamine Deficiency in Cambodian Infants with and without Beriberi
Debra Coats et al.
JOURNAL OF PEDIATRICS (2012)
Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety
Nicholas A. Meanwell
CHEMICAL RESEARCH IN TOXICOLOGY (2011)
A Highly Efficient Access to Spiroketals, Mono-unsaturated Spiroketals, and Furans: Hg(II)-Catalyzed Cyclization of Alkyne Diols and Triols
Kontham Ravindar et al.
ORGANIC LETTERS (2011)
Thiamine Status in Humans and Content of Phosphorylated Thiamine Derivatives in Biopsies and Cultured Cells
Marjorie Gangolf et al.
PLOS ONE (2010)
Synthesis and biological evaluation of pyrophosphate mimics of thiamine pyrophosphate based on a triazole scaffold
Karl M. Erixon et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2008)
Structure, mechanism and catalytic duality of thiamine-dependent enzymes
R. A. W. Frank et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Inhibition of thiamin diphosphate dependent enzymes by 3-deazathiamin diphosphate
S Mann et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2004)
Synthesis of 3-deazathiamine
D Hawksley et al.
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (2001)
Share Paper
