Diagnostic Value of Non-invasive Liver Function Tests in Liver Fibrosis and Changes in These Parameters Post-metabolic Surgery

Article Endocrinology & Metabolism

Obesity Modifies the Performance of Fibrosis Biomarkers in Nonalcoholic Fatty Liver Disease

Sami Qadri et al.

Summary: This study investigated the impact of obesity on the performance of liver fibrosis biomarkers in NAFLD and found that ADAPT and FIB-4 are the best-performing biomarkers in obese patients, unaffected by body mass index.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

Add to Collection

Article Engineering, Biomedical

Effect of bariatric surgery on fatty liver disease in obese patients: A prospective one year follow-up study

Daniel Toman et al.

Summary: The study showed that bariatric surgery in morbidly obese patients led to significant improvements in biochemical parameters and liver function, with reductions in body weight, waist circumference, and BMI, as well as improvements in liver fibrosis levels.

BIOMEDICAL PAPERS-OLOMOUC (2022)

Add to Collection

Review Surgery

Impact of Bariatric Surgery on Carotid Intima-Media Thickness in Patients with Morbid Obesity: a Prospective Study and Review of the Literature

Nima Nabavi et al.

Summary: This study aimed to evaluate the effect of substantial weight loss after bariatric surgery on carotid intima-media thickness (CIMT). The results showed that bariatric surgery resulted in significant reduction in CIMT, metabolic syndrome factors, and liver stiffness in patients with morbid obesity.

OBESITY SURGERY (2022)

Add to Collection

Article Medicine, General & Internal

Triglyceride and Glucose Index as a Screening Tool for Nonalcoholic Liver Disease in Patients with Metabolic Syndrome

Anca Maria Amzolini et al.

Summary: This study found an association between the TyG index and histopathological features of NAFLD lesions, suggesting it can be used as a tool to identify individuals at risk for NAFLD.

JOURNAL OF CLINICAL MEDICINE (2022)

Add to Collection

Article Medicine, General & Internal

Impact of bariatric surgery on circulating PCSK9 levels as a marker of cardiovascular disease risk: a meta-analysis

Tannaz Jamialahmadi et al.

Summary: This study focused on PCSK9 changes in obese patients following bariatric surgery, showing a significant decrease in PCSK9 and LDL-C post-surgery. The decrease of PCSK9 may serve as an independent surrogate marker for improving the risk of atherosclerotic cardiovascular disease following bariatric surgery.

ARCHIVES OF MEDICAL SCIENCE (2022)

Add to Collection

Review Medicine, General & Internal

The Effect of Bariatric Surgery on Circulating Levels of Monocyte Chemoattractant Protein-1: A Systematic Review and Meta-Analysis

Tannaz Jamialahmadi et al.

Summary: This meta-analysis found that bariatric surgery significantly decreases MCP-1 concentration, but there was no association between the changes in BMI and absolute difference in MCP-1 levels before and after the surgery. However, a linear relationship between the changes in MCP-1 and length of follow-up was proven.

JOURNAL OF CLINICAL MEDICINE (2022)

Add to Collection

Review Medicine, General & Internal

Effect of Bariatric Surgery on Flow-Mediated Vasodilation as a Measure of Endothelial Function: A Systematic Review and Meta-Analysis

Tannaz Jamialahmadi et al.

Summary: This study found that bariatric surgery significantly improved flow mediated vasodilation (FMD) and this improvement increased over time. The improvement in endothelial function was independent of weight loss or a reduction in blood pressure.

JOURNAL OF CLINICAL MEDICINE (2022)

Add to Collection

Review Biotechnology & Applied Microbiology

The Effect of Bariatric Surgery on Circulating Levels of Lipoprotein (a): A Meta-analysis

Tannaz Jamialahmadi et al.

Summary: This meta-analysis aimed to analyze the association between bariatric surgery and lipoprotein (a) (Lp(a)) concentrations. The results of the analysis, which included 13 studies, showed a significant decrease in circulating Lp(a) levels after bariatric surgery.

BIOMED RESEARCH INTERNATIONAL (2022)

Add to Collection

Review Medicine, General & Internal

Effect of Bariatric Surgery on Intima Media Thickness: A Systematic Review and Meta-Analysis

Tannaz Jamialahmadi et al.

Summary: This meta-analysis study showed that bariatric surgery significantly reduced IMT, with the reduction remaining robust in sensitivity analysis. The study did not find a relationship between changes in IMT and changes in BMI or duration of follow-up after bariatric surgery, but subgroup analysis indicated a greater reduction in IMT after laparoscopic sleeve gastrectomy (LSG) compared to Roux-en-Y gastric bypass (RYGB).

JOURNAL OF CLINICAL MEDICINE (2022)

Add to Collection

Review Medicine, General & Internal

The non-invasive assessment of hepatic fibrosis

Gina Gheorghe et al.

Summary: Hepatic diseases cause approximately 2 million deaths per year worldwide, with liver fibrosis being a crucial factor in many chronic liver diseases. Recent research has focused on non-invasive methods for evaluating hepatic fibrosis as an alternative to the invasive liver biopsy.

JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION (2021)

Add to Collection

Article Gastroenterology & Hepatology

Prevalence of clinically relevant liver fibrosis due to nonalcoholic fatty liver disease in Indian individuals with type 2 diabetes

Mohammad Shafi Kuchay et al.

Summary: In Indian individuals with type 2 diabetes, there is a high prevalence of fatty liver disease and liver fibrosis, which are associated with factors such as body mass index, liver enzyme levels, and lipid profile.

JGH OPEN (2021)

Add to Collection

Article

The Effect of Bariatric Surgery on Circulating Levels of Oxidized Low-Density Lipoproteins Is Apparently Independent of Changes in Body Mass Index: A Systematic Review and Meta-Analysis

Tannaz Jamialahmadi et al.

Oxidative Medicine and Cellular Longevity (2021)

Add to Collection

Article Surgery

Performance of Noninvasive Liver Fibrosis Tests in Morbidly Obese Patients with Nonalcoholic Fatty Liver Disease

Saleh A. Alqahtani et al.

Summary: In a study of morbidly obese patients, NFS, FIB-4, and APRI were found to be ineffective at detecting advanced fibrosis but were valuable for excluding it. At optimal thresholds, the tests had good NPV but low PPV, and combining them did not improve performance. Additional research is needed to develop new NITs with high positive predictive value.

OBESITY SURGERY (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Bariatric Surgery and Cardiovascular Outcomes in Patients With Obesity and Cardiovascular Disease: A Population-Based Retrospective Cohort Study

Aristithes G. Doumouras et al.

Summary: This study indicates that bariatric surgery is associated with reduced incidence of major adverse cardiovascular events in patients with cardiovascular disease and obesity, particularly in those with heart failure and ischemic heart disease. These findings suggest the potential benefits of bariatric surgery in improving cardiovascular outcomes and warrant further investigation through large-scale randomized trials.

CIRCULATION (2021)

Add to Collection

Article Endocrinology & Metabolism

Performance of non-invasive fibrosis scores in non-alcoholic fatty liver disease with and without morbid obesity

Andreas Drolz et al.

Summary: The study assessed the applicability and reliability of non-invasive fibrosis scores in NAFLD patients, finding that FIB-4 score accurately predicts advanced fibrosis in all BMI stages, while NFS tends to overestimate fibrosis in morbidly obese NAFLD patients. Adjustments may be needed for accurate assessment.

INTERNATIONAL JOURNAL OF OBESITY (2021)

Add to Collection

Review Surgery

Impact of Bariatric Surgery on Pulse Wave Velocity as a Measure of Arterial Stiffness: a Systematic Review and Meta-analysis

Tannaz Jamialahmadi et al.

Summary: This study conducted a meta-analysis revealing a significant decrease in pulse wave velocity after bariatric surgery, which could serve as an independent surrogate marker of improvement in ASCVD risk. Furthermore, there was no significant correlation found between changes in PWV and initial BMI, BMI changes, or duration of follow-up.

OBESITY SURGERY (2021)

Add to Collection

Article Gastroenterology & Hepatology

The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease

Mohammed Eslam et al.

HEPATOLOGY INTERNATIONAL (2020)

Add to Collection

Review Endocrinology & Metabolism

NAFLD as a continuum: from obesity to metabolic syndrome and diabetes

Amelio F. Godoy-Matos et al.

DIABETOLOGY & METABOLIC SYNDROME (2020)

Add to Collection

Article Gastroenterology & Hepatology

BYPASS VS. SLEEVE AND ITS EFFECTS IN NON-ALCOHOLIC FATTY LIVER DISEASE: WHAT IS THE BEST TECHNIQUE?

Marcos Bertozzi Goldoni et al.

ABCD-ARQUIVOS BRASILEIROS DE CIRURGIA DIGESTIVA-BRAZILIAN ARCHIVES OF DIGESTIVE SURGERY (2020)

Add to Collection

Article Surgery

Measurement of Liver Stiffness with 2D-Shear Wave Elastography (2D-SWE) in Bariatric Surgery Candidates Reveals Acceptable Diagnostic Yield Compared to Liver Biopsy

Tannaz Jamialahmadi et al.

OBESITY SURGERY (2019)

Add to Collection

Article Gastroenterology & Hepatology

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

Naga Chalasani et al.

HEPATOLOGY (2018)

Add to Collection

Article Cardiac & Cardiovascular Systems

The nonalcoholic fatty liver disease (NAFLD) fibrosis score, cardiovascular risk stratification and a strategy for secondary prevention with ezetimibe

Tracey G. Simon et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2018)

Add to Collection

Article Surgery

Modified thresholds for fibrosis risk scores in nonalcoholic fatty liver disease are necessary in the obese

Geraldine J. Ooi et al.

OBESITY SURGERY (2017)

Add to Collection

Article Endocrinology & Metabolism

Can FIB4 and NAFLD fibrosis scores help endocrinologists refer patients with non-alcoholic fat liver disease to a hepatologist?

Rodrigo Bremer Nones et al.

ARCHIVES OF ENDOCRINOLOGY METABOLISM (2017)

Add to Collection

Article Gastroenterology & Hepatology

Global Epidemiology of Nonalcoholic Fatty Liver Disease-Meta-Analytic Assessment of Prevalence, Incidence, and Outcomes

Zobair M. Younossi et al.

HEPATOLOGY (2016)

Add to Collection

Review Gastroenterology & Hepatology

Reversibility of liver fibrosis

Mengxi Sun et al.

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2015)

Add to Collection

Article Gastroenterology & Hepatology

EASL–EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma

et al.

JOURNAL OF HEPATOLOGY (2015)

Add to Collection

Review Endocrinology & Metabolism

Bariatric Surgery as Potential Treatment for Nonalcoholic Fatty Liver Disease: A Future Treatment by Choice or by Chance?

Shuja Hafeez et al.

JOURNAL OF OBESITY (2013)

Add to Collection

Editorial Material Gastroenterology & Hepatology

Non-Alcoholic Fatty Liver Disease and Obesity: Not All About Body Mass Index

Mangesh R. Pagadala et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2012)

Add to Collection

Article Gastroenterology & Hepatology

Association of Nonalcoholic Fatty Liver Disease With Components of Metabolic Syndrome According to Body Mass Index in Korean Adults

Young-Min Kwon et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2012)

Add to Collection

Article Surgery

Effect of Bariatric Surgery on Liver Fibrosis

Myriam Moretto et al.

OBESITY SURGERY (2012)

Add to Collection

Review Pathology

Pathogenesis of Liver Fibrosis

Virginia Hernandez-Gea et al.

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 6 (2011)

Add to Collection

Article Gastroenterology & Hepatology

Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest)

Thierry Poynard et al.

BMC GASTROENTEROLOGY (2010)

Add to Collection

Article Gastroenterology & Hepatology

Noninvasive laboratory tests proposed for predicting cirrhosis in patients with chronic hepatitis C are also useful in patients with non-alcoholic steatohepatitis

Hideki Fujii et al.

JOURNAL OF GASTROENTEROLOGY (2009)

Add to Collection

Article Medical Laboratory Technology

Standardization of ROC curve areas for diagnostic evaluation of liver fibrosis markers based on prevalences of fibrosis stages

Thierry Poynard et al.

CLINICAL CHEMISTRY (2007)

Add to Collection

Article Gastroenterology & Hepatology

The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD

Paul Angulo et al.

HEPATOLOGY (2007)

Add to Collection

Article Gastroenterology & Hepatology

Comparison and validation of simple noninvasive tests for prediction of fibrosis in chronic hepatitis C

C Lackner et al.

HEPATOLOGY (2005)

Add to Collection

Review Gastroenterology & Hepatology

Evaluation of liver fibrosis: A concise review

NH Afdhal et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2004)

Add to Collection

Diagnostic Value of Non-invasive Liver Function Tests in Liver Fibrosis and Changes in These Parameters Post-metabolic Surgery

Related references

Export Citation

Share Paper