4.4 Article

Towards an integrated radiofrequency safety concept for implant carriers in MRI based on sensor-equipped implants and parallel transmission

Journal

NMR IN BIOMEDICINE
Volume 36, Issue 7, Pages -

Publisher

WILEY
DOI: 10.1002/nbm.4900

Keywords

active implantable medical devices; implant safety; parallel transmission; RF heating; simulation; virtual sensor

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This study integrates the safety assessment of implant carriers in MRI with pTx technology. It proposes a comprehensive safety concept that combines real-time monitoring with physical sensors for quantifying implant-related heating. Simulation experiments and optimization algorithms are used to find the best excitation scheme that ensures both overall and local safety.
To protect implant carriers in MRI from excessive radiofrequency (RF) heating it has previously been suggested to assess that hazard via sensors on the implant. Other work recommended parallel transmission (pTx) to actively mitigate implant-related heating. Here, both ideas are integrated into one comprehensive safety concept where native pTx safety (without implant) is ensured by state-of-the-art field simulations and the implant-specific hazard is quantified in situ using physical sensors. The concept is demonstrated by electromagnetic simulations performed on a human voxel model with a simplified spinal-cord implant in an eight-channel pTx body coil at 3T. To integrate implant and native safety, the sensor signal must be calibrated in terms of an established safety metric (e.g., specific absorption rate [SAR]). Virtual experiments show that E-field and implant-current sensors are well suited for this purpose, while temperature sensors require some caution, and B1 probes are inadequate. Based on an implant sensor matrix Qs, constructed in situ from sensor readings, and precomputed native SAR limits, a vector space of safe RF excitations is determined where both global (native) and local (implant-related) safety requirements are satisfied. Within this safe-excitation subspace, the solution with the best image quality in terms of Bthorn1 magnitude and homogeneity is then found by a straightforward optimization algorithm. In the investigated example, the optimized pTx shim provides a 3-fold higher mean Bthorn1 magnitude compared with circularly polarized excitation for a maximum implant-related temperature increase.Delta T = 1K. To date, sensor-equipped implants interfaced to a pTx scanner exist as demonstrator items in research labs, but commercial devices are not yet within sight. This paper aims to demonstrate the significant benefits of such an approach and how this could impact implant-related RF safety in MRI. Today, the responsibility for safe implant scanning lies with the implant manufacturer and the MRI operator; within the sensor

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