4.8 Letter

Six-Month Follow-up after a Fourth BNT162b2 Vaccine Dose

Journal

NEW ENGLAND JOURNAL OF MEDICINE
Volume 387, Issue 22, Pages 2092-2094

Publisher

MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMc2211283

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A fourth dose of the BNT162b2 vaccine resulted in a smaller improvement in immunity compared to a third dose, and this improvement disappeared completely after 13 weeks.
Follow-up after a Fourth BNT162b2 Vaccine DoseAlthough a third vaccine dose showed an improved and sustained level of protection as compared with a second dose, the improvement in immunity from a fourth dose was smaller and had waned completely by 13 weeks after administration.

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