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Childhood body mass index and multiple sclerosis risk: a long-term cohort study
Kassandra L. Munger et al.
MULTIPLE SCLEROSIS JOURNAL (2013)
M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
Veronique E. Miron et al.
NATURE NEUROSCIENCE (2013)
Cerebral hypoperfusion in multiple sclerosis is reversible and mediated by endothelin-1
Miguel D'haeseleer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects
Nikolaos A. Patsopoulos et al.
PLOS GENETICS (2013)
Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination
Wolfgang Brueck et al.
ACTA NEUROPATHOLOGICA (2012)
Kinetics of Proinflammatory Monocytes in a Model of Multiple Sclerosis and Its Perturbation by Laquinimod
Manoj K. Mishra et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Laminin regulates postnatal oligodendrocyte production by promoting oligodendrocyte progenitor survival in the subventricular zone
Jenne Relucio et al.
GLIA (2012)
Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease
Azeb Tadesse Argaw et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Serum nitric oxide concentrations in patients with multiple sclerosis and patients with epilepsy
Saida Ibragic et al.
JOURNAL OF NEURAL TRANSMISSION (2012)
Age at onset as a determinant of presenting phenotype and initial relapse recovery in multiple sclerosis
M. Cossburn et al.
MULTIPLE SCLEROSIS JOURNAL (2012)
High body mass index before age 20 is associated with increased risk for multiple sclerosis in both men and women
Anna K. Hedstrom et al.
MULTIPLE SCLEROSIS JOURNAL (2012)
Metabolic Modulation of Cytokine-Induced Brain Endothelial Adhesion Molecule Expression
Ganta Vijay Chaitanya et al.
MICROCIRCULATION (2012)
Placebo-Controlled Trial of Oral Laquinimod for Multiple Sclerosis
Giancarlo Comi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Laquinimod, a Quinoline-3-Carboxamide, Induces Type II Myeloid Cells That Modulate Central Nervous System Autoimmunity
Ulf Schulze-Topphoff et al.
PLOS ONE (2012)
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
Jeffrey J. Iliff et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation
Dimitrios Davalos et al.
NATURE COMMUNICATIONS (2012)
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation
Anny-Claude Luissint et al.
FLUIDS AND BARRIERS OF THE CNS (2012)
Multiple sclerosis normal-appearing white matter: Pathology-imaging correlations
Natalia M. Moll et al.
ANNALS OF NEUROLOGY (2011)
Human Placental Pericytes Poorly Stimulate and Actively Regulate Allogeneic CD4 T Cell Responses
Cheryl L. Maier et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
Ralf A. Linker et al.
BRAIN (2011)
Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises
Annika Armulik et al.
DEVELOPMENTAL CELL (2011)
Brain microvascular pericytes are immunoactive in culture: cytokine, chemokine, nitric oxide, and LRP-1 expression in response to lipopolysaccharide
Andrej Kovac et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Regulation of Oligodendrocyte Development and Myelination by Glucose and Lactate
Johanne E. Rinholm et al.
JOURNAL OF NEUROSCIENCE (2011)
Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluid
Samia Ragheb et al.
MULTIPLE SCLEROSIS JOURNAL (2011)
FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation
Ji Woong Choi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Cigarette Smoke Components Induce Matrix Metalloproteinase-1 in Aortic Endothelial Cells through Inhibition of mTOR Signaling
Vincent Lemaitre et al.
TOXICOLOGICAL SCIENCES (2011)
Gene expression analysis of the microvascular compartment in multiple sclerosis using laser microdissected blood vessels
Paula Cunnea et al.
ACTA NEUROPATHOLOGICA (2010)
Astrocytes: biology and pathology
Michael V. Sofroniew et al.
ACTA NEUROPATHOLOGICA (2010)
CNS Elevation of Vascular and Not Mucosal Addressin Cell Adhesion Molecules in Patients with Multiple Sclerosis
Rachel Allavena et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Glatiramer Acetate A Review of its Use in Relapsing-Remitting Multiple Sclerosis and in Delaying the Onset of Clinically Definite Multiple Sclerosis
Natalie J. Carter et al.
DRUGS (2010)
The Perivascular Astroglial Sheath Provides a Complete Covering of the Brain Microvessels: An Electron Microscopic 3D Reconstruction
Thomas Misje Mathiisen et al.
GLIA (2010)
Sphingosine 1-Phosphate Receptor 1 and 3 Are Upregulated in Multiple Sclerosis Lesions
Ruben Van Doorn et al.
GLIA (2010)
Astrocyte-Restricted Ablation of Interleukin-17-Induced Act1-Mediated Signaling Ameliorates Autoimmune Encephalomyelitis
Zizhen Kang et al.
IMMUNITY (2010)
NG2 Glia Generate New Oligodendrocytes But Few Astrocytes in a Murine Experimental Autoimmune Encephalomyelitis Model of Demyelinating Disease
Richa B. Tripathi et al.
JOURNAL OF NEUROSCIENCE (2010)
Pericytes regulate the blood-brain barrier
Annika Armulik et al.
NATURE (2010)
Pericytes are required for blood-brain barrier integrity during embryogenesis
Richard Daneman et al.
NATURE (2010)
Longitudinal Examination of Obesity and Cognitive Function: Results from the Baltimore Longitudinal Study of Aging
John Gunstad et al.
NEUROEPIDEMIOLOGY (2010)
Increased blood vessel density and endothelial cell proliferation in multiple sclerosis cerebral white matter
Janet E. Holley et al.
NEUROSCIENCE LETTERS (2010)
A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
Ludwig Kappos et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Promotion of Central Nervous System Remyelination by Induced Differentiation of Oligodendrocyte Precursor Cells
Sha Mi et al.
ANNALS OF NEUROLOGY (2009)
An Oligovascular Niche: Cerebral Endothelial Cells Promote the Survival and Proliferation of Oligodendrocyte Precursor Cells
Ken Arai et al.
JOURNAL OF NEUROSCIENCE (2009)
Biochemical Evidence of Atherosclerosis Progression Mediated by Increased Oxidative Stress in Apolipoprotein E-Deficient Spontaneously Hyperlipidemic Mice Exposed to Chronic Cigarette Smoke
Masaru Kunitomo et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2009)
White matter hemodynamic abnormalities precede sub-cortical gray matter changes in multiple sclerosis
Andrew W. Varga et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2009)
Progeny of Olig2-Expressing Progenitors in the Gray and White Matter of the Adult Mouse Cerebral Cortex
Leda Dimou et al.
JOURNAL OF NEUROSCIENCE (2008)
Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
Ludwig Kappos et al.
LANCET (2008)
PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice
Leanne E. Rivers et al.
NATURE NEUROSCIENCE (2008)
NG2 cells generate both oligodendrocytes and gray matter astrocytes
Xiaoqin Zhu et al.
DEVELOPMENT (2008)
Mid-life adiposity factors relate to blood-brain barrier integrity in late life
D. R. Gustafson et al.
JOURNAL OF INTERNAL MEDICINE (2007)
Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?
Christina Marik et al.
BRAIN (2007)
Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors
Florian Mullershausen et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Obesity impairs vascular relaxation in human subjects: hyperglycemia exaggerates drenergic vasoconstriction - Arterial dysfunction in obesity and diabetes
William I. Sivitz et al.
JOURNAL OF DIABETES AND ITS COMPLICATIONS (2007)
Loss of aquaporin 4 in lesions of neuromyelitis optica: distinction from multiple sclerosis
T. Misu et al.
BRAIN (2007)
Persistent endothelial abnormalities and blood-brain barrier leak in primary and secondary progressive multiple sclerosis
S. Leech et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2007)
Glatiramer acetate in primary progressive multiple sclerosis: Results of a multinational, multicenter, double-blind, placebo-controlled trial
Jerry S. Wolinsky et al.
ANNALS OF NEUROLOGY (2007)
Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation
Zsuzsanna Orosz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis
Kassandra L. Munger et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)
Pattern of hemodynamic impairment in multiple sclerosis: Dynamic susceptibility contrast perfusion MR imaging at 3.0 T
Sumita Adhya et al.
NEUROIMAGE (2006)
Low cerebrospinal fluid insulin levels in obese humans
W. Kern et al.
DIABETOLOGIA (2006)
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
CH Polman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis
CMP Vos et al.
NEUROBIOLOGY OF DISEASE (2005)
Blocking adhesion molecules as therapy for multiple sclerosis: Natalizumab
L Steinman
NATURE REVIEWS DRUG DISCOVERY (2005)
Temporal relationship between elevation of Epstein-Barr virus antibody titers and initial onset of neurological symptoms in multiple sclerosis
LI Levin et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)
Differential activation of astrocytes by innate and adaptive immune stimuli
PA Carpentier et al.
GLIA (2005)
Pulsatile flow increases the expression of eNOS, ET-1, and prostacyclin in a novel in vitro coculture model of the retinal vasculature
TE Walshe et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
M Krumbholz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Impaired brain angiogenesis and neuronal apoptosis induced by conditional homozygous inactivation of vascular endothelial growth factor
S Raab et al.
THROMBOSIS AND HAEMOSTASIS (2004)
Induction of IL-10 in rat peritoneal macrophages and dendritic cells by glatiramer acetate
S Jung et al.
JOURNAL OF NEUROIMMUNOLOGY (2004)
Peroxynitrite-mediated oxidative modification of low-density lipoprotein by aqueous extracts of cigarette smoke and the preventive effect of fluvastatin
Y Yamaguchi et al.
ATHEROSCLEROSIS (2004)
Vitamin D intake and incidence of multiple sclerosis
KL Munger et al.
NEUROLOGY (2004)
Microvascular abnormality in relapsing-remitting multiple sclerosis: Perfusion MR imaging findings in normal-appearing white matter
M Law et al.
RADIOLOGY (2004)
Asynchronous shear stress and circumferential strain reduces endothelial NO synthase and cyclooxygenase-2 but induces endothelin-1 gene expression in endothelial cells
MB Dancu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Cortical GABA interneurons in neurovascular coupling: Relays for subcortical vasoactive pathways
B Cauli et al.
JOURNAL OF NEUROSCIENCE (2004)
Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival
DC Darland et al.
DEVELOPMENTAL BIOLOGY (2003)
Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood-brain barrier leakage and active demyelination
J Kirk et al.
JOURNAL OF PATHOLOGY (2003)
Epidemiology of smoking-induced cardiovascular disease
DM Burns
PROGRESS IN CARDIOVASCULAR DISEASES (2003)
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
H Gerhardt et al.
JOURNAL OF CELL BIOLOGY (2003)
Nitric oxide metabolite determinations reveal continuous inflammation in multiple sclerosis
AI Danilov et al.
JOURNAL OF NEUROIMMUNOLOGY (2003)
Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases
F Aboul-Enein et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2003)
Why does remyelination fail in multiple sclerosis?
RJM Franklin
NATURE REVIEWS NEUROSCIENCE (2002)
Stable expression of angiopoietin-1 and other markers by cultured pericytes: Phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo
C Sundberg et al.
LABORATORY INVESTIGATION (2002)
Glatiramer acetate and IFN-β act on dendritic cells in multiple sclerosis
Y Hussien et al.
JOURNAL OF NEUROIMMUNOLOGY (2001)
An energy budget for signaling in the grey matter of the brain
D Attwell et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2001)
Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions
JW Peterson et al.
ANNALS OF NEUROLOGY (2001)
Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement
JGN Garcia et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Antiproliferative properties of sphingosine-1-phosphate in human hepatic myofibroblasts
A Pébay et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
Requirement for leptin in the induction and progression of autoimmune encephalomyelitis
G Matarese et al.
JOURNAL OF IMMUNOLOGY (2001)
European/Canadian multicenter, double-blind, randomized, placebo-controlled study of the effects of glatiramer acetate on magnetic resonance imaging-measured disease activity and burden in patients with relapsing multiple sclerosis
G Comi et al.
ANNALS OF NEUROLOGY (2001)
Plasma interleukin-6, tumour necrosis factor α and blood cytokine production in type 2 diabetes
JC Pickup et al.
LIFE SCIENCES (2000)
Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors
Q Zhou et al.
NEURON (2000)
Sonic hedgehog-regulateld oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system
QR Lu et al.
NEURON (2000)