Related references
Note: Only part of the references are listed.Inference of CRISPR Edits from Sanger Trace Data
David Conant et al.
CRISPR JOURNAL (2022)
Nonlinear control of transcription through enhancer-promoter interactions
Jessica Zuin et al.
NATURE (2022)
Building regulatory landscapes reveals that an enhancer can recruit cohesin to create contact domains, engage CTCF sites and activate distant genes
Niels J. Rinzema et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2022)
Ctcfhaploinsufficiency mediates intron retention in a tissue-specific manner
Adel B. Alharbi et al.
RNA BIOLOGY (2021)
WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation
Ning Qing Liu et al.
NATURE GENETICS (2021)
Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation
Naoki Kubo et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2021)
Distinct properties and functions of CTCF revealed by a rapidly inducible degron system
Jing Luan et al.
CELL REPORTS (2021)
How subtle changes in 3D structure can create large changes in transcription
Jordan Yupeng Xiao et al.
ELIFE (2021)
DEAD-Box RNA Helicases and Genome Stability
Michael Cargill et al.
GENES (2021)
DNA Methylation Regulates Alternative Polyadenylation via CTCF and the Cohesin Complex
Vishal Nanavaty et al.
MOLECULAR CELL (2020)
Exploring the Interaction between the SWI/SNF Chromatin Remodeling Complex and the Zinc Finger Factor CTCF
Mariangela Valletta et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Condensin II Counteracts Cohesin and RNA Polymerase II in the Establishment of 3D Chromatin Organization
M. Jordan Rowley et al.
CELL REPORTS (2019)
Mammalian ISWI and SWI/SNF selectively mediate binding of distinct transcription factors
Darko Barisic et al.
NATURE (2019)
Principles of genome folding into topologically associating domains
Quentin Szabo et al.
SCIENCE ADVANCES (2019)
Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture
Alexandra Despang et al.
NATURE GENETICS (2019)
Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF
Anders S. Hansen et al.
MOLECULAR CELL (2019)
RNA polymerases as moving barriers to condensin loop extrusion
Hugo B. Brandao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation
Antoine Campagne et al.
NATURE COMMUNICATIONS (2019)
Human gene essentiality
Istvan Bartha et al.
NATURE REVIEWS GENETICS (2018)
Chromatin organization by an interplay of loop extrusion and compartmental segregation
Johannes Nuebler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Two independent modes of chromatin organization revealed by cohesin removal
Wibke Schwarzer et al.
NATURE (2017)
Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl
Georg A. Busslinger et al.
NATURE (2017)
Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens
Traver Hart et al.
G3-GENES GENOMES GENETICS (2017)
CTCF-Mediated Chromatin Loops between Promoter and Gene Body Regulate Alternative Splicing across Individuals
Mariana Ruiz-Velasco et al.
CELL SYSTEMS (2017)
Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins
Gordana Wutz et al.
EMBO JOURNAL (2017)
A mechanism of cohesin-dependent loop extrusion organizes zygotic genome architecture
Johanna Gassler et al.
EMBO JOURNAL (2017)
Multiscale 3D Genome Rewiring during Mouse Neural Development
Boyan Bonev et al.
CELL (2017)
Cohesin Loss Eliminates All Loop Domains
Suhas S. P. Rao et al.
CELL (2017)
Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization
Elphege P. Nora et al.
CELL (2017)
The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension
Judith H. I. Haarhuis et al.
CELL (2017)
Insulator dysfunction and oncogene activation in IDH mutant gliomas
William A. Flavahan et al.
NATURE (2016)
BAGEL: a computational framework for identifying essential genes from pooled library screens
Traver Hart et al.
BMC BIOINFORMATICS (2016)
TAD disruption as oncogenic driver
Anne-Laure Valton et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2016)
Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals
Lionel A. Sanz et al.
MOLECULAR CELL (2016)
Formation of new chromatin domains determines pathogenicity of genomic duplications
Martin Franke et al.
NATURE (2016)
Activation of proto-oncogenes by disruption of chromosome neighborhoods
Denes Hnisz et al.
SCIENCE (2016)
Breaking TADs: How Alterations of Chromatin Domains Result in Disease
Dario G. Lupianez et al.
TRENDS IN GENETICS (2016)
Rapid Protein Depletion in Human Cells by Auxin-Inducible Degron Tagging with Short Homology Donors
Toyoaki Natsume et al.
CELL REPORTS (2016)
Formation of Chromosomal Domains by Loop Extrusion
Geoffrey Fudenberg et al.
CELL REPORTS (2016)
The Chromatin Remodelling Enzymes SNF2H and SNF2L Position Nucleosomes adjacent to CTCF and Other Transcription Factors
Nicola Wiechens et al.
PLOS GENETICS (2016)
Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders
Liis Uuskula-Reimand et al.
GENOME BIOLOGY (2016)
Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions
Dario G. Lupianez et al.
CELL (2015)
High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
Traver Hart et al.
CELL (2015)
Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition
Nova Fong et al.
MOLECULAR CELL (2015)
CTCF Binding Polarity Determines Chromatin Looping
Elzo de Wit et al.
MOLECULAR CELL (2015)
Condensin-driven remodelling of X chromosome topology during dosage compensation
Emily Crane et al.
NATURE (2015)
Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes
Adrian L. Sanborn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation
Varun Narendra et al.
SCIENCE (2015)
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
Suhas S. P. Rao et al.
CELL (2014)
Measuring error rates in genomic perturbation screens: gold standards for human functional genomics
Traver Hart et al.
MOLECULAR SYSTEMS BIOLOGY (2014)
dREAM co-operates with insulator-binding proteins and regulates expression at divergently paired genes
Michael Korenjak et al.
NUCLEIC ACIDS RESEARCH (2014)
A Functional Insulator Screen Identifies NURF and dREAM Components to Be Required for Enhancer-Blocking
Dorte Bohla et al.
PLOS ONE (2014)
Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment
Jennifer E. Phillips-Cremins et al.
CELL (2013)
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran et al.
NATURE PROTOCOLS (2013)
Three-Dimensional Folding and Functional Organization Principles of the Drosophila Genome
Tom Sexton et al.
CELL (2012)
The long-range interaction landscape of gene promoters
Amartya Sanyal et al.
NATURE (2012)
Topological domains in mammalian genomes identified by analysis of chromatin interactions
Jesse R. Dixon et al.
NATURE (2012)
Spatial partitioning of the regulatory landscape of the X-inactivation centre
Elphege P. Nora et al.
NATURE (2012)
Self-organization of domain structures by DNA-loop-extruding enzymes
Elnaz Alipour et al.
NUCLEIC ACIDS RESEARCH (2012)
Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes
Xingguo Li et al.
BLOOD (2011)
Control of Embryonic Stem Cell Lineage Commitment by Core Promoter Factor, TAF3
Zhe Liu et al.
CELL (2011)
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
Sanjeev Shukla et al.
NATURE (2011)
Mediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA
Hongjie Yao et al.
GENES & DEVELOPMENT (2010)
Mediator and cohesin connect gene expression and chromatin architecture
Michael H. Kagey et al.
NATURE (2010)
The SAGA continues: expanding the cellular role of a transcriptional co-activator complex
S. P. Baker et al.
ONCOGENE (2007)
CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus
Erik Splinter et al.
GENES & DEVELOPMENT (2006)
RNA interference machinery influences the nuclear organization of a chromatin insulator
Elissa P. Lei et al.
NATURE GENETICS (2006)
Genome-wide mapping of the cohesin complex in the yeast Saccharomyces cerevisiae
EF Glynn et al.
PLOS BIOLOGY (2004)
Cohesin relocation from sites of chromosomal loading to places of convergent transcription
A Lengronne et al.
NATURE (2004)