4.6 Editorial Material

Co-agonist therapeutics come of age for obesity

Journal

NATURE REVIEWS ENDOCRINOLOGY
Volume 19, Issue 2, Pages 66-67

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41574-022-00788-y

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GLP1 analogues are approved treatments for obesity, but novel therapies are needed for improved weight loss and the direct treatment of other comorbidities, such as non-alcoholic fatty liver disease. Recent research published in 2022 demonstrates that co-agonist combinations of GLP1 with other hormones offer clinically significant advancements.
Glucagon-like peptide 1 (GLP1) analogues are licensed options for obesity, but new treatments are required to obtain better weight loss and to directly address other co-morbidities, such as non-alcoholic fatty liver disease. Research published in 2022 shows that co-agonist combinations of GLP1 with other hormones provide clinically important advances.

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