Related references
Note: Only part of the references are listed.Structural variants shape driver combinations and outcomes in pediatric high-grade glioma
Frank P. B. Dubois et al.
NATURE CANCER (2022)
Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants
Raul Bardini Bressan et al.
CELL STEM CELL (2021)
Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma
Kosuke Funato et al.
CELL STEM CELL (2021)
An atlas of cortical arealization identifies dynamic molecular signatures
Aparna Bhaduri et al.
NATURE (2021)
Single-cell chromatin state analysis with Signac
Tim Stuart et al.
NATURE METHODS (2021)
Joint profiling of histone modifications and transcriptome in single cells from mouse brain
Chenxu Zhu et al.
NATURE METHODS (2021)
Polycomb repressive complex 2 in the driver's seat of childhood and young adult brain tumours
Brian Krug et al.
TRENDS IN CELL BIOLOGY (2021)
Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage
Elisa Le Boiteux et al.
MOLECULAR ONCOLOGY (2021)
Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia
Ugomma C. Eze et al.
NATURE NEUROSCIENCE (2021)
Life-long oligodendrocyte development and plasticity
Akiko Nishiyama et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2021)
A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR
Philipp Sievers et al.
NEURO-ONCOLOGY (2021)
Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas
Jerome Fortin et al.
CANCER CELL (2020)
HOX gene cluster (de)regulation in brain: from neurodevelopment to malignant glial tumours
Celine S. Goncalves et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2020)
Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons
Corina Nagy et al.
NATURE NEUROSCIENCE (2020)
Understanding the Deadly Silence of Posterior Fossa A Ependymoma
Grant L. Lin et al.
MOLECULAR CELL (2020)
H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2
Siddhant U. Jain et al.
MOLECULAR CELL (2020)
Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones
Jay F. Sarthy et al.
ELIFE (2020)
Histone H3.3G34-Mutant Intemeuron Progenitors Co-opt PDGFRA for Gliomagenesis
Carol C. L. Chen et al.
CELL (2020)
H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation
Ashot S. Harutyunyan et al.
CELL REPORTS (2020)
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
Gabriela S. Kinker et al.
NATURE GENETICS (2020)
EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma
Jens-Martin Huebner et al.
NEURO-ONCOLOGY (2019)
ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis
Christine M. Hoeman et al.
NATURE COMMUNICATIONS (2019)
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas
Brian Krug et al.
CANCER CELL (2019)
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
Maria C. Vladoiu et al.
NATURE (2019)
Comprehensive Integration of Single-Cell Data
Tim Stuart et al.
CELL (2019)
Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq
Dylan Kotliar et al.
ELIFE (2019)
GenPipes: an open-source framework for distributed and scalable genomic analyses
Mathieu Bourgey et al.
GIGASCIENCE (2019)
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape
Daniel N. Weinberg et al.
NATURE (2019)
Stalled developmental programs at the root of pediatric brain tumors
Selin Jessa et al.
NATURE GENETICS (2019)
Fast, sensitive and accurate integration of single-cell data with Harmony
Ilya Korsunsky et al.
NATURE METHODS (2019)
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells
Roberta Ragazzini et al.
NATURE COMMUNICATIONS (2019)
Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State
Surya Nagaraja et al.
MOLECULAR CELL (2019)
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis
Ashot S. Harutyunyan et al.
NATURE COMMUNICATIONS (2019)
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling
Stephen C. Mack et al.
NATURE (2018)
Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas
Kristian W. Pajtler et al.
ACTA NEUROPATHOLOGICA (2018)
Capturing the Onset of PRC2-Mediated Repressive Domain Formation
Ozgur Oksuz et al.
MOLECULAR CELL (2018)
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
Mariella G. Filbin et al.
SCIENCE (2018)
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma
James M. Stafford et al.
SCIENCE ADVANCES (2018)
Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas
Andrea Piunti et al.
NATURE MEDICINE (2017)
SCENIC: single-cell regulatory network inference and clustering
Sara Aibar et al.
NATURE METHODS (2017)
Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma
Alan Mackay et al.
CANCER CELL (2017)
Models of human core transcriptional regulatory circuitries
Violaine Saint-Andre et al.
GENOME RESEARCH (2016)
deepTools2: a next generation web server for deep-sequencing data analysis
Fidel Ramirez et al.
NUCLEIC ACIDS RESEARCH (2016)
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
Itay Tirosh et al.
SCIENCE (2016)
Identification of proliferative progenitors associated with prominent postnatal growth of the pons
Robert A. Lindquist et al.
NATURE COMMUNICATIONS (2016)
Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments
Neva C. Durand et al.
CELL SYSTEMS (2016)
VisRseq: R-based visual framework for analysis of sequencing data
Hamid Younesy et al.
BMC BIOINFORMATICS (2015)
CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation
Varun Narendra et al.
SCIENCE (2015)
Tissue-based map of the human proteome
Mathias Uhlen et al.
SCIENCE (2015)
The Molecular Signatures Database Hallmark Gene Set Collection
Arthur Liberzon et al.
CELL SYSTEMS (2015)
changepoint: AnRPackage for Changepoint Analysis
Rebecca Killick et al.
Journal of Statistical Software (2015)
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
Yang Liao et al.
BIOINFORMATICS (2014)
Trimmomatic: a flexible trimmer for Illumina sequence data
Anthony M. Bolger et al.
BIOINFORMATICS (2014)
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
Suhas S. P. Rao et al.
CELL (2014)
Polycomb-Dependent H3K27me1 and H3K27me2 Regulate Active Transcription and Enhancer Fidelity
Karin J. Ferrari et al.
MOLECULAR CELL (2014)
The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
Gang Wu et al.
NATURE GENETICS (2014)
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
Pawel Buczkowicz et al.
NATURE GENETICS (2014)
Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma
Kathryn R. Taylor et al.
NATURE GENETICS (2014)
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma
Adam M. Fontebasso et al.
NATURE GENETICS (2014)
A High-Resolution Spatiotemporal Atlas of Gene Expression of the Developing Mouse Brain
Carol L. Thompson et al.
NEURON (2014)
Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome
David A. Orlando et al.
CELL REPORTS (2014)
Impact of artifact removal on ChIP quality metrics in ChIP-seq and ChIP-exo data
Thomas S. Carroll et al.
FRONTIERS IN GENETICS (2014)
STAR: ultrafast universal RNA-seq aligner
Alexander Dobin et al.
BIOINFORMATICS (2013)
Evaluation of Histone 3 Lysine 27 Trimethylation (H3K27me3) and Enhancer of Zest 2 (EZH2) in Pediatric Glial and Glioneuronal Tumors Shows Decreased H3K27me3 in H3F3A K27M Mutant Glioblastomas
Sriram Venneti et al.
BRAIN PATHOLOGY (2013)
Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration
Helga Thorvaldsdottir et al.
BRIEFINGS IN BIOINFORMATICS (2013)
Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas
Sebastian Bender et al.
CANCER CELL (2013)
Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
Jakob Loven et al.
CELL (2013)
A High-Resolution Enhancer Atlas of the Developing Telencephalon
Axel Visel et al.
CELL (2013)
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran et al.
CELL (2013)
A smart local moving algorithm for large-scale modularity-based community detection
Ludo Waltman et al.
EUROPEAN PHYSICAL JOURNAL B (2013)
Hox Genes: Choreographers in Neural Development, Architects of Circuit Organization
Polyxeni Philippidou et al.
NEURON (2013)
Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
Peter W. Lewis et al.
SCIENCE (2013)
K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
Dong-Anh Khuong-Quang et al.
ACTA NEUROPATHOLOGICA (2012)
Mechanistic Differences in the Transcriptional Interpretation of Local and Long-Range Shh Morphogen Signaling
Tony Oosterveen et al.
DEVELOPMENTAL CELL (2012)
The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation
Allison M. Bond et al.
DEVELOPMENTAL NEUROBIOLOGY (2012)
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Jeremy Schwartzentruber et al.
NATURE (2012)
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
Gang Wu et al.
NATURE GENETICS (2012)
Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma
Michelle Monje et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Dynamic Architecture of Hox Gene Clusters
Daan Noordermeer et al.
SCIENCE (2011)
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
Sven Heinz et al.
MOLECULAR CELL (2010)
Building a bridal chamber: development of the thalamus
Steffen Scholpp et al.
TRENDS IN NEUROSCIENCES (2010)
The Hox genes and their roles in oncogenesis
Nilay Shah et al.
NATURE REVIEWS CANCER (2010)
Fast and accurate short read alignment with Burrows-Wheeler transform
Heng Li et al.
BIOINFORMATICS (2009)
FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain
Benoit V. Jacquet et al.
DEVELOPMENT (2009)
Genome-wide atlas of gene expression in the adult mouse brain
Ed S. Lein et al.
NATURE (2007)
Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells
Noritaka Masahira et al.
DEVELOPMENTAL BIOLOGY (2006)
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
BE Bernstein et al.
CELL (2006)
Control of developmental regulator's by polycomb in human embryonic stem cells
TI Lee et al.
CELL (2006)
Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage
N Kessaris et al.
NATURE NEUROSCIENCE (2006)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
A subset of oligodendrocytes generated from radial glia in the dorsal spinal cord
M Fogarty et al.
DEVELOPMENT (2005)
Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling
J Cai et al.
NEURON (2005)