Shining light on diselenide bonds

Post-translational modification of proteins is widely used for studying biological processes; however, competing reactions can provide numerous challenges. Now, a visible-light photocatalytic diselenide contraction enables the highly chemoselective functionalization of selenopeptides and proteins under mild conditions.

Automated summary

A visible-light photocatalytic diselenide contraction has been developed for the chemoselective functionalization of selenopeptides and proteins under mild conditions, providing a new method for studying post-translational modification of proteins.