New diterpenoid alkaloids from Delphinium pachycentrum Hemsl

Article Chemistry, Medicinal

Eleven new C19-diterpenoid alkaloids from Delphinium elatum cv. Pacific Giant

Hiroshi Yamashita et al.

Summary: New C-19-diterpenoid alkaloids were isolated and identified, along with known C-19-diterpenoid alkaloids. These compounds showed cytotoxic activity against human tumor cell lines.

JOURNAL OF NATURAL MEDICINES (2022)

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Review Biochemistry & Molecular Biology

Norditerpenoid alkaloids from Aconitum and Delphinium: structural relevance in medicine, toxicology, and metabolism

Ashraf M. A. Qasem et al.

Summary: Norditerpenoid alkaloids (NDA) are complex natural products with important pharmacological activities. Research has shown that understanding the metabolism of NDA is crucial for their development as drugs.

NATURAL PRODUCT REPORTS (2022)

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Article Plant Sciences

Three new diterpenoid alkaloids from Delphinium tatsienense

Tianpeng Yin et al.

Summary: Three new diterpenoid alkaloids were isolated from the whole plants of Delphinium tatsienense Franch., a folk medicine in China for wind-toxin syndrome treatment. The structures of these alkaloids were determined through extensive spectroscopic analyses. Their potential anti-inflammatory effects were evaluated against NO production in LPS-stimulated RAW 264.7 macrophages.

PHYTOCHEMISTRY LETTERS (2021)

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Review Biochemistry & Molecular Biology

Flavonoids from tribe Delphineae (Ranunculaceae): Phytochemical review and chemotaxonomic value

Tianpeng Yin et al.

Summary: This review presents the first summary of flavonoids isolated from three genera in the Delphineae tribe of the Ranunculaceae family, demonstrating a high chemical diversity among these compounds, with flavonols being the dominant group. Flavonoids in Delphineae plants have chemotaxonomic significance and can serve as valuable markers for identifying specific species within the tribe.

BIOCHEMICAL SYSTEMATICS AND ECOLOGY (2021)

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Review Biochemistry & Molecular Biology

Classification, Toxicity and Bioactivity of Natural Diterpenoid Alkaloids

Amin Mahmood Thawabteh et al.

Summary: Diterpenoid alkaloids are complex natural compounds primarily produced by plants and marine organisms, with potential medicinal and toxic effects, exhibiting a wide range of biological activities. This review focuses on the structure, classification, toxicity, and bioactivity of natural diterpenoid alkaloids.

MOLECULES (2021)

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Review Chemistry, Multidisciplinary