Related references
Note: Only part of the references are listed.CRISPR/Cas9 Mediated Knockout of Cyclooxygenase-2 Gene Inhibits Invasiveness in A2058 Melanoma Cells
Cathleen Haase-Kohn et al.
CELLS (2022)
Solid-Phase Synthesis of Cereblon-Recruiting Selective Histone Deacetylase 6 Degraders (HDAC6 PROTACs) with Antileukemic Activity
Laura Sinatra et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
Development of Fluorinated Peptoid-Based Histone Deacetylase (HDAC) Inhibitors for Therapy-Resistant Acute Leukemia
Nina Ressing et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
Carboranyl Analogues of Mefenamic Acid and Their Biological Evaluation
Liridona Useini et al.
ACS OMEGA (2022)
Exploring Nitric Oxide (NO)-Releasing Celecoxib Derivatives as Modulators of Radioresponse in Pheochromocytoma Cells
Florian Brandt et al.
MOLECULES (2022)
Role of Fluorination in the Histone Deacetylase 6 (HDAC6) Selectivity of Benzohydroxamate-Based Inhibitors
Giovanni Sandrone et al.
ACS MEDICINAL CHEMISTRY LETTERS (2021)
Borinostats: solid-phase synthesis of carborane-capped histone deacetylase inhibitors with a tailor-made selectivity profile
Christoph Selg et al.
CHEMICAL SCIENCE (2021)
Hydroxamic Acids Immobilized on Resins (HAIRs): Synthesis of Dual-Targeting HDAC Inhibitors and HDAC Degraders (PROTACs)
Laura Sinatra et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)
Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups
Nina Ressing et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Cyclooxygenase-2 Inhibitors as a Therapeutic Target in Inflammatory Diseases
Miguel D. Ferrer et al.
CURRENT MEDICINAL CHEMISTRY (2019)
Polypharmacology by Design: A Medicinal Chemist's Perspective on Multitargeting Compounds
Ewgenij Proschak et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Targeting Chromatin Remodeling for Cancer Therapy
Jasmine Kaur et al.
CURRENT MOLECULAR PHARMACOLOGY (2019)
Targeting Cyclooxygenase-2 in Pheochromocytoma and Paraganglioma: Focus on Genetic Background
Martin Ullrich et al.
CANCERS (2019)
Fluorinated Analogues of the Histone Deacetylase Inhibitor Vorinostat (Zolinza): Validation of a Chiral Hybrid Bioisostere, BITE
Nathalie Erdeljac et al.
ACS MEDICINAL CHEMISTRY LETTERS (2019)
Structure-Activity and Structure-Toxicity Relationships of Peptoid-Based Histone Deacetylase Inhibitors with Dual-Stage Antiplasmodial Activity
Marcel K. W. Mackwitz et al.
CHEMMEDCHEM (2019)
Cyclooxygenase-2 in cancer: A review
Nasser Hashemi Goradel et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Synthesis of Peptoid-Based Class I-Selective Histone Deacetylase Inhibitors with Chemosensitizing Properties
Viktoria Krieger et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Dual or multi-targeting inhibitors: The next generation anticancer agents
Nulgumnalli Manjunathaiah Raghavendra et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Synopsis of arachidonic acid metabolism: A review
Violette Said Hanna et al.
JOURNAL OF ADVANCED RESEARCH (2018)
Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor
Sanil Bhatia et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Epigenetic mechanisms as a new approach in cancer treatment: An updated review
Masoumeh Fardi et al.
GENES & DISEASES (2018)
A perspective on multi-target drug discovery and design for complex diseases
Rona R. Ramsay et al.
CLINICAL AND TRANSLATIONAL MEDICINE (2018)
Multimodal HDAC Inhibitors with Improved Anticancer Activity
Rainer Schobert et al.
CURRENT CANCER DRUG TARGETS (2018)
Designing multi-targeted agents: An emerging anticancer drug discovery paradigm
Rong-geng Fu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Histone Deacetylase Inhibitors as Anticancer Drugs
Tomas Eckschlager et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Synergistic antitumor effects of the combined treatment with an HDAC6 inhibitor and a COX-2 inhibitor through activation of PTEN
Guanhua Zhang et al.
ONCOLOGY REPORTS (2017)
Synthesis of novel hybrids of pyrazole and coumarin as dual inhibitors of COX-2 and 5-LOX
Fa-Qian Shen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase
Idris Raji et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
Bicyclic-Capped Histone Deacetylase 6 Inhibitors with Improved Activity in a Model of Axonal Charcot-Marie-Tooth Disease
Sida Shen et al.
ACS CHEMICAL NEUROSCIENCE (2016)
Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways
Nicholas S. Kirkby et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Inside HDACs with more selective HDAC inhibitors
Joelle Roche et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Cyclooxygenase-2 is associated with malignant phenotypes in human lung cancer
Weiying Li et al.
ONCOLOGY LETTERS (2016)
Epigenetic polypharmacology: from combination therapy to multitargeted drugs
Angel R. de Lera et al.
CLINICAL EPIGENETICS (2016)
Cyclooxygenase-2: A Role in Cancer Stem Cell Survival and Repopulation of Cancer Cells during Therapy
Lisa Y. Pang et al.
STEM CELLS INTERNATIONAL (2016)
Polypharmacology: the rise of multitarget drugs over combination therapies
Michela Rosini
FUTURE MEDICINAL CHEMISTRY (2014)
Polypharmacology: Challenges and Opportunities in Drug Discovery
Andrew Anighoro et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Cancer-related inflammation and treatment effectiveness
Connie I. Diakos et al.
LANCET ONCOLOGY (2014)
Radiolabeled COX-2 Inhibitors for Non-Invasive Visualization of COX-2 Expression and Activity - A Critical Update
Markus Laube et al.
MOLECULES (2013)
The Anti-Tumor Effect of HDAC Inhibition in a Human Pancreas Cancer Model Is Significantly Improved by the Simultaneous Inhibition of Cyclooxygenase 2
Olivier Peulen et al.
PLOS ONE (2013)
HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications
Omar Khan et al.
IMMUNOLOGY AND CELL BIOLOGY (2012)
Coxibs and Other Nonsteroidal Anti-Inflammatory Drugs in Animal Models of Cancer Chemoprevention
Susan M. Fischer et al.
CANCER PREVENTION RESEARCH (2011)
Histone deacetylase inhibitors:: mechanism of action and therapeutic use in cancer
Olaia Martinez-Iglesias et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2008)
Method for measuring the logarithm of the octanol-water partition coefficient by using short octadecyl-poly(vinyl alcohol) high-performance liquid chromatography columns
SF Donovan et al.
JOURNAL OF CHROMATOGRAPHY A (2002)
Share Paper
