4.6 Article

Enhancement of the Protective Activity of Vanillic Acid against Tetrachloro-Carbon (CCl4) Hepatotoxicity in Male Rats by the Synthesis of Silver Nanoparticles (AgNPs)

Related references

Note: Only part of the references are listed.
Review Pharmacology & Pharmacy

Special Section on Pharmacokinetics and ADME of Biological Therapeutics-Minireview Absorption, Distribution, Metabolism, and Excretion of US Food and Drug Administration-Approved Antisense Oligonucleotide Drugs

Julia M. Migliorati et al.

Summary: Absorption, distribution, metabolism, and excretion (ADME) are key biological processes that determine a drug's pharmacokinetic parameters and directly impact its efficacy and adverse reactions. This review focuses on the unique ADME characteristics of antisense oligonucleotide (ASO) drugs, which have diverse modes of drug actions and great potential for treating diseases untreatable by small molecule-based drugs. A meta-analysis of 10 FDA-approved ASO drugs provides comprehensive insights into their formulation, dosage, administration sites, distribution, metabolism, and excretion, improving our understanding of their therapeutic efficacy and potential adverse reactions.

DRUG METABOLISM AND DISPOSITION (2022)

Article Biochemistry & Molecular Biology

Vanillic Acid, a Bioactive Phenolic Compound, Counteracts LPS-Induced Neurotoxicity by Regulating c-Jun N-Terminal Kinase in Mouse Brain

Rahat Ullah et al.

Summary: The study demonstrated that vanillic acid (V.A) exhibits neuroprotective effects against lipopolysaccharides (LPS)-induced neuroinflammatory processes by inhibiting the JNK signaling pathway mediated by LPS/RAGE. Furthermore, V.A was found to attenuate synaptic loss and improve memory performance induced by LPS, suggesting its potential as a neuroprotective and neurotherapeutic agent for various neurological disorders.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Polymer Science

Application of Chitosan/Alginate Nanocomposite Incorporated with Phycosynthesized Iron Nanoparticles for Efficient Remediation of Chromium

Fahad M. Almutairi et al.

Summary: The study innovatively synthesized nanopolymer composites using biopolymers and nanomaterials to remove hexavalent chromium (Cr6+) from water. By combining chitosan and alginate with phycosynthesized iron nanoparticles, effective removal of Cr6+ was achieved through adsorption.

POLYMERS (2021)

Article Integrative & Complementary Medicine

Green coffee methanolic extract and silymarin protect against CCl4-induced hepatotoxicity in albino male rats

Haddad A. El Rabey et al.

Summary: This study aimed to investigate the protective effects of green coffee methanolic extract, silymarin, and their combination on CCl4-induced liver toxicity in male rats. The results showed that these substances successfully protected the rats against CCl4-induced hepatotoxicity, demonstrating antioxidant activity.

BMC COMPLEMENTARY MEDICINE AND THERAPIES (2021)

Article Chemistry, Multidisciplinary

Roles of Akt and ERK in mTOR-Dependent Antidepressant Effects of Vanillic Acid

Han-Wen Chuang et al.

ACS OMEGA (2020)

Article Polymer Science

Effectual Anticancer Potentiality of Loaded Bee Venom onto Fungal Chitosan Nanoparticles

Adel Alalawy et al.

INTERNATIONAL JOURNAL OF POLYMER SCIENCE (2020)

Article Cell Biology

Vanillic Acid Alleviates Acute Myocardial Hypoxia/Reoxygenation Injury by Inhibiting Oxidative Stress

Xiuya Yao et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)

Article Nanoscience & Nanotechnology

The Efficacy of AgNO3 Nanoparticles Alone and Conjugated with Imipenem for Combating Extensively Drug-Resistant Pseudomonas aeruginosa

Mahsa Shahbandeh et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

Article Biochemistry & Molecular Biology

Protective effect of vanillic acid against benzo(a)pyrene induced lung cancer in Swiss albino mice

Sathesh Kanna Velli et al.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2019)

Article Chemistry, Multidisciplinary

Phenolic compounds and biological activities of rye (Secale cereale L.) grains

Katarina Kulichova et al.

OPEN CHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Augmented control of drug-resistant Candida spp. via fluconazole loading into fungal chitosan nanoparticles

Haddad A. El Rabey et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Review Biotechnology & Applied Microbiology

Nano based drug delivery systems: recent developments and future prospects

Jayanta Kumar Patra et al.

JOURNAL OF NANOBIOTECHNOLOGY (2018)

Review Chemistry, Multidisciplinary

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

Alexandra-Cristina Burdusel et al.

NANOMATERIALS (2018)

Article Medicine, Research & Experimental

Capparis spinosa leaves extract: Source of bioantioxidants with nephroprotective and hepatoprotective effects

Nizar Tlili et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

Article Integrative & Complementary Medicine

Liquid and vapour-phase antifungal activities of essential oils against Candida albicans and non-albicans Candida

Narcisa Mandras et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2016)

Article Integrative & Complementary Medicine

The hepatoprotective activity of olive oil and Nigella sativa oil against CCl4 induced hepatotoxicity in male rats

Madeha N. Al-Seeni et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2016)

Review Biochemistry & Molecular Biology

Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches

Xi-Feng Zhang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article Integrative & Complementary Medicine

Bioactive Polyphenols from the Methanol Extract of Cnicus arvensis (L.) Roth Demonstrated Antinociceptive and Central Nervous System Depressant Activities in Mice

Mahmudur Rahman et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2015)

Article Integrative & Complementary Medicine

Hepatoprotective Effect of Silymarin (Silybum marianum) on Hepatotoxicity Induced by Acetaminophen in Spontaneously Hypertensive Rats

Abel Felipe Freitag et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2015)

Review Biochemistry & Molecular Biology

The Role of Oxidative Stress and Antioxidants in Liver Diseases

Sha Li et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Review Biochemistry & Molecular Biology

ROS Function in Redox Signaling and Oxidative Stress

Michael Schieber et al.

CURRENT BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Antioxidative Properties of Vanillic Acid Esters in Multiple Antioxidant Assays

Akihiro Tai et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2012)

Article Plant Sciences

Possible mechanism of hepatoprotective activity of Azadirachta indica leaf extract:: Part II

RR Chattopadhyay

JOURNAL OF ETHNOPHARMACOLOGY (2003)