4.6 Article

PMMA/ABS/CoCl2 Composites for Pharmaceutical Applications: Thermal, Antimicrobial, Antibiofilm, and Antioxidant Studies

Journal

MOLECULES
Volume 27, Issue 22, Pages -

Publisher

MDPI
DOI: 10.3390/molecules27227669

Keywords

biofilms; bacteria; degradation; inorganic filler

Funding

  1. Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research, King Faisal University, Saudi Arabia [Grant1869]

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In this study, PMMA/ABS/CoCl2 ternary composite films were fabricated and their chemical structure, thermal properties, and biological properties were evaluated. The results demonstrated that the PMMA/ABS/cobalt chloride composites showed enhanced thermal stability, antibacterial activity, and antioxidant capacity, suitable for high-quality plastics and pharmaceutical applications.
In this study, PMMA/ABS/CoCl2 ternary composite films were fabricated by the solution casting technique. The different weight ratios of cobalt chloride (<= 10 wt) were incorporated into the PMMA/ABS blend (80:20). The chemical structure and thermal properties of the synthesized composites were assessed by FT-IR, TGA, and XRD. The biological properties of ternary composites, such as in vitro antibacterial activity and antioxidant capacity, were investigated. The enhanced thermal stability and promising antibacterial, selective antibiofilm, and potential antioxidant properties of PMMA/ABS/cobalt chloride composites demonstrated that they can be used for high-quality plastics and in many pharmaceutical applications.

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