Related references
Note: Only part of the references are listed.Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function
Danyang He et al.
IMMUNITY (2022)
Central nervous system macrophages in progressive multiple sclerosis: relationship to neurodegeneration and therapeutics
Emily Kamma et al.
JOURNAL OF NEUROINFLAMMATION (2022)
CellRank for directed single-cell fate mapping
Marius Lange et al.
NATURE METHODS (2022)
Oligodendrocyte death and myelin loss in the cuprizone model: an updated overview of the intrinsic and extrinsic causes of cuprizone demyelination
Martin Zirngibl et al.
MOLECULAR NEURODEGENERATION (2022)
Specification of CNS macrophage subsets occurs postnatally in defined niches
Takahiro Masuda et al.
NATURE (2022)
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain
Samuel E. Marsh et al.
NATURE NEUROSCIENCE (2022)
Abnormal oxidative metabolism in the cuprizone mouse model of demyelination: An in vivo NIRS-MRI study
Mada Hashem et al.
NEUROIMAGE (2022)
Intranasal anti-caspase-1 therapy preserves myelin and glucose metabolism in a model of progressive multiple sclerosis
Leina B. Saito et al.
GLIA (2021)
Nebulosa recovers single-cell gene expression signals by kernel density estimation
Jose Alquicira-Hernandez et al.
BIOINFORMATICS (2021)
NINJ1 mediates plasma membrane rupture during lytic cell death
Nobuhiko Kayagaki et al.
NATURE (2021)
The Ins and Outs of Central Nervous System Inflammation-Lessons Learned from Multiple Sclerosis
Valeria Ramaglia et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 39 (2021)
Activated microglia drive demyelination via CSF1R signaling
Dave E. Marzan et al.
GLIA (2021)
White matter aging drives microglial diversity
Shima Safaiyan et al.
NEURON (2021)
Dying cells fan the flames of inflammation
Kim Newton et al.
SCIENCE (2021)
Phagocytic clearance of apoptotic, necrotic, necroptotic and pyroptotic cells
Georgia K. Atkin-Smith
BIOCHEMICAL SOCIETY TRANSACTIONS (2021)
The CD33 short isoform is a gain-of-function variant that enhances Aβ1-42 phagocytosis in microglia
Abhishek Bhattacherjee et al.
MOLECULAR NEURODEGENERATION (2021)
Barcoded viral tracing of single-cell interactions in central nervous system inflammation
Iain C. Clark et al.
SCIENCE (2021)
Integrated analysis of multimodal single-cell data
Yuhan Hao et al.
CELL (2021)
Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord
Lindsay M. Milich et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2021)
A lymphocyte-microglia-astrocyte axis in chronic active multiple sclerosis
Martina Absinta et al.
NATURE (2021)
Neuroinflammatory astrocyte subtypes in the mouse brain
Philip Hasel et al.
NATURE NEUROSCIENCE (2021)
Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time
Priya Prakash et al.
CHEMICAL SCIENCE (2021)
NicheNet: modeling intercellular communication by linking ligands to target genes
Robin Browaeys et al.
NATURE METHODS (2020)
Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion
Jason R. Plemel et al.
SCIENCE ADVANCES (2020)
Runx3 prevents spontaneous colitis by directing the differentiation of anti-inflammatory mononuclear phagocytes
Shay Hantisteanu et al.
PLOS ONE (2020)
Putative cell type discovery from single-cell gene expression data
Zhichao Miao et al.
NATURE METHODS (2020)
Astrocytes and microglia play orchestrated roles and respect phagocytic territories during neuronal corpse removal in vivo
Eyiyemisi C. Damisah et al.
SCIENCE ADVANCES (2020)
Generalizing RNA velocity to transient cell states through dynamical modeling
Volker Bergen et al.
NATURE BIOTECHNOLOGY (2020)
Increased blood-brain barrier hyperpermeability coincides with mast cell activation early under cuprizone administration
John Shelestak et al.
PLOS ONE (2020)
Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction
Hiroyuki Konishi et al.
EMBO JOURNAL (2020)
Human fetal microglia acquire homeostatic immune-sensing properties early in development
L. Kracht et al.
SCIENCE (2020)
Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation
Karpagam Srinivasan et al.
CELL REPORTS (2020)
Microglia and Astrocytes in Disease: Dynamic Duo or Partners in Crime?
Shane A. Liddelow et al.
TRENDS IN IMMUNOLOGY (2020)
Master Regulator Activating Transcription Factor 3 (ATF3) in Metabolic Homeostasis and Cancer
Hui-Chen Ku et al.
FRONTIERS IN ENDOCRINOLOGY (2020)
Ferroptosis Mediates Cuprizone-Induced Loss of Oligodendrocytes and Demyelination
Priya Jhelum et al.
JOURNAL OF NEUROSCIENCE (2020)
Microglia Diversity in Health and Multiple Sclerosis
Sameera Zia et al.
FRONTIERS IN IMMUNOLOGY (2020)
Iron Metabolism in Oligodendrocytes and Astrocytes, Implications for Myelination and Remyelination
Veronica T. Cheli et al.
ASN NEURO (2020)
Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution
Takahiro Masuda et al.
NATURE (2019)
Integrative single-cell analysis
Tim Stuart et al.
NATURE REVIEWS GENETICS (2019)
Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation
Marta Joana Costa Jordao et al.
SCIENCE (2019)
Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment
Kayla V. Myers et al.
MOLECULAR CANCER (2019)
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
Hannah Van Hove et al.
NATURE NEUROSCIENCE (2019)
The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques
Carlo Sala Frigerio et al.
CELL REPORTS (2019)
Comprehensive Integration of Single-Cell Data
Tim Stuart et al.
CELL (2019)
Macrophages at CNS interfaces: ontogeny and function in health and disease
Katrin Kierdorf et al.
NATURE REVIEWS NEUROSCIENCE (2019)
Mapping microglia states in the human brain through the integration of high-dimensional techniques
Roman Sankowski et al.
NATURE NEUROSCIENCE (2019)
Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination
Leslie Kirby et al.
NATURE COMMUNICATIONS (2019)
Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model
Elizabeth Spangenberg et al.
NATURE COMMUNICATIONS (2019)
GLUT6 is a lysosomal transporter that is regulated by inflammatory stimuli and modulates glycolysis in macrophages
Shotaro Maedera et al.
FEBS LETTERS (2019)
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
Timothy R. Hammond et al.
IMMUNITY (2019)
Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing
Qingyun Li et al.
NEURON (2019)
Tmem119-EGFP and Tmem119-CreERT2 transgenic mice for labeling and manipulating microglia
Tobias Kaiser et al.
ENEURO (2019)
Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression
Christoph Hafemeister et al.
GENOME BIOLOGY (2019)
Mechanisms of lysophosphatidylcholine-induced demyelination: A primary lipid disrupting myelinopathy
Jason R. Plemel et al.
GLIA (2018)
Single-Cell Transcriptomics and Fate Mapping of Ependymal Cells Reveals an Absence of Neural Stem Cell Function
Prajay T. Shah et al.
CELL (2018)
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Lorenzo Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2018)
High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease
Dunja Mrdjen et al.
IMMUNITY (2018)
Deficient Surveillance and Phagocytic Activity of Myeloid Cells Within Demyelinated Lesions in Aging Mice Visualized by Ex Vivo Live Multiphoton Imaging
Khalil S. Rawji et al.
JOURNAL OF NEUROSCIENCE (2018)
A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex
Suijuan Zhong et al.
NATURE (2018)
Biochemically altered myelin triggers autoimmune demyelination
Andrew V. Caprariello et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Clustering trees: a visualization for evaluating clusterings at multiple resolutions
Luke Zappia et al.
GIGASCIENCE (2018)
Unique microglia recovery population revealed by single-cell RNAseq following neurodegeneration
Tuan Leng Tay et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)
Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis
Ana Mendanha Falcao et al.
NATURE MEDICINE (2018)
SCANPY: large-scale single-cell gene expression data analysis
F. Alexander Wolf et al.
GENOME BIOLOGY (2018)
An updated histological classification system for multiple sclerosis lesions
Tanja Kuhlmann et al.
ACTA NEUROPATHOLOGICA (2017)
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
Susanne Krasemann et al.
IMMUNITY (2017)
Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis
Jason R. Plemel et al.
JOURNAL OF CELL BIOLOGY (2017)
NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes
Leslie Freeman et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
SCENIC: single-cell regulatory network inference and clustering
Sara Aibar et al.
NATURE METHODS (2017)
Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures
Christopher J. Bohlen et al.
NEURON (2017)
Dietary cholesterol promotes repair of demyelinated lesions in the adult brain
Stefan A. Berghoff et al.
NATURE COMMUNICATIONS (2017)
Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution
Hansruedi Mathys et al.
CELL REPORTS (2017)
Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model
Stefan A. Berghoff et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease
Hadas Keren-Shaul et al.
CELL (2017)
Origin, fate and dynamics of macrophages at central nervous system interfaces
Tobias Goldmann et al.
NATURE IMMUNOLOGY (2016)
Diffusion kurtosis imaging probes cortical alterations and white matter pathology following cuprizone induced demyelination and spontaneous remyelination
C. Guglielmetti et al.
NEUROIMAGE (2016)
TREM2 regulates microglial cell activation in response to demyelination in vivo
Claudia Cantoni et al.
ACTA NEUROPATHOLOGICA (2015)
Inefficient clearance of myelin debris by microglia impairs remyelinating processes
Antoine Lampron et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Activation of Necroptosis in Multiple Sclerosis
Dimitry Ofengeim et al.
CELL REPORTS (2015)
IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunity
Magdalena Kocur et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Pathologic Heterogeneity Persists in Early Active Multiple Sclerosis Lesions
Imke Metz et al.
ANNALS OF NEUROLOGY (2014)
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
Christopher N. Parkhurst et al.
CELL (2013)
Short-Term Cuprizone Feeding Induces Selective Amino Acid Deprivation with Concomitant Activation of an Integrated Stress Response in Oligodendrocytes
Johannes Goldberg et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2013)
NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration
Liya Qin et al.
GLIA (2013)
Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways
Won-Suk Chung et al.
NATURE (2013)
A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
Tobias Goldmann et al.
NATURE NEUROSCIENCE (2013)
Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells
Jun Suzuki et al.
SCIENCE (2013)
Clearing the Dead: Apoptotic Cell Sensing, Recognition, Engulfment, and Digestion
Amelia Hochreiter-Hufford et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
The cuprizone model: regional heterogeneity of pathology
Stig Wergeland et al.
APMIS (2012)
Functional regulation of HIF-1a under normoxiauis there more than post-translational regulation?
A. Kuschel et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2012)
Will the real multiple sclerosis please stand up?
Peter K. Stys et al.
NATURE REVIEWS NEUROSCIENCE (2012)
The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18
Sushmita Jha et al.
JOURNAL OF NEUROSCIENCE (2010)
In toxic demyelination oligodendroglial cell death occurs early and is FAS independent
Amke Hesse et al.
NEUROBIOLOGY OF DISEASE (2010)
Remyelination protects axons from demyelination-associated axon degeneration
K. A. Irvine et al.
BRAIN (2008)
MHC class II exacerbates demyelination in vivo independently of T cells
Meenaxi M. Hiremath et al.
JOURNAL OF NEUROIMMUNOLOGY (2008)
Hypoxia, HIF1 and glucose metabolism in the solid tumour
Nicholas C. Denko
NATURE REVIEWS CANCER (2008)
Lack of interferon-beta leads to accelerated remyelination in a toxic model of central nervous system demyelination
Corinna Trebst et al.
ACTA NEUROPATHOLOGICA (2007)
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
Bahareh Ajami et al.
NATURE NEUROSCIENCE (2007)
Transcription factor Tfec contributes to the IL-4-inducible expression of a small group of genes in mouse macrophages including the granulocyte colony-stimulating factor receptor
M Rehli et al.
JOURNAL OF IMMUNOLOGY (2005)
Phagocytosis of apoptotic inflammatory cells by microglia and its therapeutic implications: Termination of CNS autoimmune inflammation and modulation by interferon-beta
A Chan et al.
GLIA (2003)
Aminophospholipid asymmetry: A matter of life and death
K Balasubramanian et al.
ANNUAL REVIEW OF PHYSIOLOGY (2003)
Absence of macrophage-inflammatory protein-1α delays central nervous system demyelination in the presence of an intact blood-brain barrier
EJ McMahon et al.
JOURNAL OF IMMUNOLOGY (2001)
Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1
GL Semenza
JOURNAL OF CLINICAL INVESTIGATION (2000)