Related references
Note: Only part of the references are listed.First-in-Humans Evaluation of Safety and Dosimetry of 64Cu-LLP2A for PET Imaging
Richard Laforest et al.
JOURNAL OF NUCLEAR MEDICINE (2023)
Characterization of folic acid-functionalized PLA-PEG nanomicelle to deliver Letrozole: A nanoinformatics study
Neda Rostami et al.
IET NANOBIOTECHNOLOGY (2022)
Cancer Stem Cells and Circulatory Tumor Cells Promote Breast Cancer Metastasis
RamaRao Malla et al.
CLINICAL BREAST CANCER (2022)
A hypothetical proposal to employ meperidine and tamoxifen in treatment of glioblastoma. Role of P-glycoprotein, ceramide and metabolic pathways
Meric A. Altinoz et al.
CLINICAL NEUROLOGY AND NEUROSURGERY (2022)
Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective
Kunal S. Taskar et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2022)
Recent advances in anti-multidrug resistance for nano-drug delivery system
Changduo Wang et al.
DRUG DELIVERY (2022)
Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy
Dirk Zboralski et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2022)
Peptidomimetics: An Overview of Recent Medicinal Chemistry Efforts toward the Discovery of Novel Small Molecule Inhibitors
Giovanna Li Petri et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
The potential roles of retinoids in combating drug resistance in cancer: implications of ATP-binding cassette (ABC) transporters
Mohamed R. Abdelaal et al.
OPEN BIOLOGY (2022)
Peptidomimetics in Silico
Cristina Tomasella et al.
MOLECULAR INFORMATICS (2021)
Bioactive Peptides as Therapeutic Adjuvants for Cancer
Nidia Quintal-Bojorquez et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2021)
A novel peptidomimetic therapeutic for selective suppression of lung cancer stem cells over non-stem cancer cells
Satya Prakash Shukla et al.
BIOORGANIC CHEMISTRY (2021)
Recent Advancements in Stimuli Responsive Drug Delivery Platforms for Active and Passive Cancer Targeting
Muhammad Abdur Rahim et al.
CANCERS (2021)
Lipidated Peptidomimetic Ligand-Functionalized HER2 Targeted Liposome as Nano-Carrier Designed for Doxorubicin Delivery in Cancer Therapy
Himgauri Naik et al.
PHARMACEUTICALS (2021)
Tumor-Associated Macrophages: Critical Players in Drug Resistance of Breast Cancer
Maoyu Xiao et al.
FRONTIERS IN IMMUNOLOGY (2021)
Multi-Arm PEG/Peptidomimetic Conjugate Inhibitors of DR6/APP Interaction Block Hematogenous Tumor Cell Extravasation
Liting Wang et al.
ADVANCED SCIENCE (2021)
Implementation of docking, molecular dynamics and free energy to investigate drug potency of novel BCR-ABLT315I inhibitors as an alternative to ponatinib
Mohammad Mahmoudi Gomari et al.
COMPUTATIONAL TOXICOLOGY (2021)
Solid-phase Synthesis of Peptidomimetics with Peptide Backbone Modifications
Aizhan Abdildinova et al.
ASIAN JOURNAL OF ORGANIC CHEMISTRY (2021)
CD44 polymorphisms and its variants, as an inconsistent marker in cancer investigations
Mohammad Mahmoudi Gomari et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2021)
Peptidomimetics: A Synthetic Tool for Inhibiting Protein-Protein Interactions in Cancer
Lloyd Mabonga et al.
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS (2020)
Silencing of STAT3 via Peptidomimetic LNP-Mediated Systemic Delivery of RNAi Downregulates PD-L1 and Inhibits Melanoma Growth
Ehexige Ehexige et al.
BIOMOLECULES (2020)
Synthesis and antiproliferative activity of sulfonamide-based peptidomimetic calpain inhibitors
Isaac O. Donkor et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2020)
First-in-Human Assessment of cRGD-ZW800-1, a Zwitterionic, Integrin-Targeted, Near-Infrared Fluorescent Peptide in Colon Carcinoma
Kim S. de Valk et al.
CLINICAL CANCER RESEARCH (2020)
Functionalizing nanoparticles with cancer-targeting antibodies: A comparison of strategies
A. C. Marques et al.
JOURNAL OF CONTROLLED RELEASE (2020)
Polyamide Backbone Modified Cell Targeting and Penetrating Peptides in Cancer Detection and Treatment
Sunil S. Shah et al.
FRONTIERS IN CHEMISTRY (2020)
Methods to Enhance the Metabolic Stability of Peptide-Based PET Radiopharmaceuticals
Brendan J. Evans et al.
MOLECULES (2020)
The Role of a Proprotein Convertase Inhibitor in Reactivation of Tumor-Associated Macrophages and Inhibition of Glioma Growth
Melanie Rose et al.
MOLECULAR THERAPY-ONCOLYTICS (2020)
Development of a Cationic Amphiphilic Helical Peptidomimetic (B18L) As A Novel Anti-Cancer Drug Lead
Yuan Lyu et al.
CANCERS (2020)
Opportunities and challenges of the tag-assisted protein purification techniques: Applications in the pharmaceutical industry
Mohammad Mahmoudi Gomari et al.
BIOTECHNOLOGY ADVANCES (2020)
Tirbanibulin Ointment 1% as a Novel Treatment for Actinic Keratosis: Phase 1 and 2 Results
Steven Kempers et al.
JOURNAL OF DRUGS IN DERMATOLOGY (2020)
Peptidomimetic toolbox for drug discovery
Elena Lenci et al.
CHEMICAL SOCIETY REVIEWS (2020)
Targeting siRNA in colorectal cancer therapy: Nanotechnology comes into view
Shahin Aghamiri et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Enhanced anti-tumor activity of the Multi-Leu peptide PACE4 inhibitor transformed into an albumin-bound tumor-targeting prodrug
Anna Kwiatkowska et al.
SCIENTIFIC REPORTS (2019)
A Guanidyl-Based Bivalent Peptidomimetic Inhibits K-Ras Prenylation and Association with c-Raf
Mai Tsubamoto et al.
CHEMISTRY-A EUROPEAN JOURNAL (2019)
Design of Peptidomimetic Functionalized Cholesterol Based Lipid Nanoparticles for Efficient Delivery of Therapeutic Nucleic Acids
Ehexige Ehexige et al.
MOLECULES (2019)
Recent developments of prostate-specific membrane antigen (PSMA)-specific radiopharmaceuticals for precise imaging and therapy of prostate cancer: an overview
Subhani M. Okarvi
CLINICAL AND TRANSLATIONAL IMAGING (2019)
Short Cationic Peptidomimetic Antimicrobials
Rajesh Kuppusamy et al.
ANTIBIOTICS-BASEL (2019)
Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-alpha-amanitin conjugates for tumor-targeting
Lizeth Bodero et al.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY (2018)
Recent advances in peptidomimetics antagonists targeting estrogen receptor alpha-coactivator interaction in cancer therapy
Weirong Qin et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
Breast cancer diagnosis: Imaging techniques and biochemical markers
Seyed Hamed Jafari et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2018)
Peptidomimetic blockade of MYB in acute myeloid leukemia
Kavitha Ramaswamy et al.
NATURE COMMUNICATIONS (2018)
B49, a BST-2-based peptide, inhibits adhesion and growth of breast cancer cells
Wadie D. Mahauad-Fernandez et al.
SCIENTIFIC REPORTS (2018)
Promising Antibiofilm Activity of Peptidomimetics
Rafael Gomes Von Borowski et al.
FRONTIERS IN MICROBIOLOGY (2018)
Design of novel lipidated peptidomimetic conjugates for targeting EGFR heterodimerization in HER2+cancer
Himgauri Naik et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
Design of a doxorubicin-peptidomimetic conjugate that targets HER2-positive cancer cells
Sandeep Pallerla et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
The proprotein convertase furin in tumour progression
Patricia Jaaks et al.
INTERNATIONAL JOURNAL OF CANCER (2017)
Dual Src Kinase/Pretubulin Inhibitor KX-01, Sensitizes ERα-negative Breast Cancers to Tamoxifen through ERα Reexpression
Muralidharan Anbalagan et al.
MOLECULAR CANCER RESEARCH (2017)
A peptidomimetic with a chiral switch is an inhibitor of epidermal growth factor receptor heterodimerization
Shanthi P. Kanthala et al.
ONCOTARGET (2017)
Co-targeting the tumor endothelium and P-selectin-expressing glioblastoma cells leads to a remarkable therapeutic outcome
Shiran Ferber et al.
ELIFE (2017)
Exploring the Role of RGD-Recognizing Integrins in Cancer
Markus Nieberler et al.
CANCERS (2017)
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
Michiru Nishita et al.
SCIENTIFIC REPORTS (2017)
From Peptides to Peptidomimetics: A Strategy Based on the Structural Features of Cyclopropane
Akira Mizuno et al.
CHEMISTRY-A EUROPEAN JOURNAL (2017)
Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer
Xiaoju Wang et al.
CANCER CELL (2017)
Peptidomimetic therapeutics: scientific approaches and opportunities
Nir Qvit et al.
DRUG DISCOVERY TODAY (2017)
Dynamic Docking of Conformationally Constrained Macrocycles: Methods and Applications
Scott E. Allen et al.
ACS CHEMICAL BIOLOGY (2016)
In vivo biokinetic and metabolic characterization of the 68Ga-labelled α5β1-selective peptidomimetic FR366
Calogero D'Alessandria et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2016)
Peptidomimetic suppresses proliferation and invasion of gastric cancer cells by fibroblast growth factor 2 signaling cascade blockage
Wulan Li et al.
ANTI-CANCER DRUGS (2016)
Facile synthesis and 18F-radiolabeling of α4β1-specific LLP2A-aryltrifluoroborate peptidomimetic conjugates
Daniel Walker et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Design, synthesis, biological evaluation and molecular docking study on peptidomimetic analogues of XK469
Qiao-Hong Xia et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Peptides and peptidomimetics in the p53/MDM2/MDM4 circuitry - a patent review
Emanuela Teveroni et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2016)
Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and grafting method
Cyril Corbet et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis
Boris Strilic et al.
NATURE (2016)
Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice
Fariba Poosti et al.
ONCOTARGET (2016)
Peptidomimetics Based On Dehydroepiandrosterone Scaffold: Synthesis, Antiproliferation Activity, Structure-Activity Relationship, and Mechanisms
Xiaohui Wang et al.
SCIENTIFIC REPORTS (2016)
Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes
Marta Pelay-Gimeno et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
Synthesis and characterization of gadolinium-Peptidomimetic complex as an αvβ3 integrin targeted MR contrast agent
Young-Seung Kim et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
Macrophages and Therapeutic Resistance in Cancer
Brian Ruffell et al.
CANCER CELL (2015)
Synthesis and Biological Evaluation of RGD Peptidomimetic-Paclitaxel Conjugates Bearing Lysosomally Cleavable Linkers
Alberto Dal Corso et al.
CHEMISTRY-A EUROPEAN JOURNAL (2015)
The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation
Kai Xu et al.
GENES & DEVELOPMENT (2015)
GDC-0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway
Lin Yang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2015)
The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal disease
Richard L. Sidman et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
ADAM8 as a drug target in pancreatic cancer
Uwe Schlomann et al.
NATURE COMMUNICATIONS (2015)
PACE4 inhibitors and their peptidomimetic analogs block prostate cancer tumor progression through quiescence induction, increased apoptosis and impaired neovascularisation
Christine Levesque et al.
ONCOTARGET (2015)
A small molecule peptidomimetic that binds to c-KIT1 G-quadruplex and exhibits antiproliferative properties in cancer cells
Ajay Chauhan et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
Interferon gamma peptidomimetic targeted to hepatic stellate cells ameliorates acute and chronic liver fibrosis in vivo
Ruchi Bansal et al.
JOURNAL OF CONTROLLED RELEASE (2014)
Design, Synthesis, and Structure-Activity Relationship Studies of a Potent PACE4 Inhibitor
Anna Kwiatkowska et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
PET Imaging of Very Late Antigen-4 in Melanoma: Comparison of 68Ga- and 64Cu-Labeled NODAGA and CB-TE1A1P-LLP2A Conjugates
Wissam Beaino et al.
JOURNAL OF NUCLEAR MEDICINE (2014)
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial
Roger Stupp et al.
LANCET ONCOLOGY (2014)
Targeted Recombinant Fusion Proteins of IFNγ and Mimetic IFNγ with PDGFβR Bicyclic Peptide Inhibits Liver Fibrogenesis In Vivo
Ruchi Bansal et al.
PLOS ONE (2014)
The Secreted Protein ANGPTL2 Promotes Metastasis of Osteosarcoma Cells Through Integrin α5β1, p38 MAPK, and Matrix Metalloproteinases
Haruki Odagiri et al.
SCIENCE SIGNALING (2014)
Effects of a novel cyclic RGD peptidomimetic on cell proliferation, migration and angiogenic activity in human endothelial cells
Roberto Fanelli et al.
VASCULAR CELL (2014)
Validation and application of a liquid chromatography-tandem mass spectrometric method for the determination of GDC-0152 in human plasma using solid-phase extraction
Young G. Shin et al.
BIOMEDICAL CHROMATOGRAPHY (2013)
High-Affinity, Small-Molecule Peptidomimetic Inhibitors of MLL1/WDR5 Protein-Protein Interaction
Hacer Karatas et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
An Antimicrobial Peptidomimetic Induces Mucorales Cell Death through Mitochondria-Mediated Apoptosis
E. Magda Barbu et al.
PLOS ONE (2013)
Synthesis and characterization of αvβ3-targeting peptidomimetic chelate conjugates for PET and SPECT imaging
Young-Seung Kim et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Cyclic RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands
Mattia Marchini et al.
CHEMISTRY-A EUROPEAN JOURNAL (2012)
Reversal of P-glycoprotein-mediated multidrug resistance by a synthetic α-aminoxy peptidomimetic
Bin Ma et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2012)
The Multi-Leu Peptide Inhibitor Discriminates Between PACE4 and Furin And Exhibits Antiproliferative Effects On Prostate Cancer Cells
Christine Levesque et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Multivalent Peptidomimetic Conjugates: A Versatile Platform for Modulating Androgen Receptor Activity
Paul M. Levine et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
Muralidharan Anbalagan et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Mimicking Peptides... In Silico
Matteo Floris et al.
MOLECULAR INFORMATICS (2012)
RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis
Fabienne Danhier et al.
MOLECULAR PHARMACEUTICS (2012)
Integrins as therapeutic targets
Simon L. Goodman et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Integrin-assisted drug delivery of nano-scaled polymer therapeutics bearing paclitaxel
Anat Eldar-Boock et al.
BIOMATERIALS (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Using Modularly Assembled Ligands To Bind RNA Internal Loops Separated by Different Distances
Jessica L. Childs-Disney et al.
CHEMBIOCHEM (2011)
The role of β3-integrins in tumor angiogenesis: context is everything
Stephen D. Robinson et al.
CURRENT OPINION IN CELL BIOLOGY (2011)
Structural and Dynamic Determinants of Protein-Peptide Recognition
Onur Dagliyan et al.
STRUCTURE (2011)
Cilengitide: The First Anti-Angiogenic Small Molecule Drug Candidate. Design, Synthesis and Clinical Evaluation
Carlos Mas-Moruno et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2010)
A Conformationally Constrained Peptidomimetic Binds to the Extracellular Region of HER2 Protein
Sashikanth Banappagari et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2010)
Ligands for Mapping αvβ3-Integrin Expression in Vivo
Margret Schottelius et al.
ACCOUNTS OF CHEMICAL RESEARCH (2009)
Apoptosis of B-cell chronic lymphocytic leukemia cells induced by a novel BH3 peptidomimetic
Fabio Ghiotto et al.
CANCER BIOLOGY & THERAPY (2009)
Cyclic RGD-Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands
Ana Sofia M. da Ressurreicao et al.
CHEMISTRY-A EUROPEAN JOURNAL (2009)
A novel Bim-BH3-derived Bcl-XL inhibitor Biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity
Raffaella Ponassi et al.
CELL CYCLE (2008)
Multimodality molecular imaging of tumor angiogenesis
Weibo Cai et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Identification and Rational Redesign of Peptide Ligands to CRIP1, A Novel Biomarker for Cancers
Jihua Hao et al.
PLOS COMPUTATIONAL BIOLOGY (2008)
Integrins in angiogenesis and lymphangiogenesis
Christie J. Avraamides et al.
NATURE REVIEWS CANCER (2008)
Treatment of hypoxia-induced retinopathy with targeted proapoptotic peptidomimetic in a mouse model of disease
Johanna Lahdenranta et al.
FASEB JOURNAL (2007)
Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX
Baoli Hu et al.
CANCER RESEARCH (2007)
Apoptosis: A review of programmed cell death
Susan Elmore
TOXICOLOGIC PATHOLOGY (2007)
Angiogenesis in cancer
Naoyo Nishida et al.
VASCULAR HEALTH AND RISK MANAGEMENT (2006)
Targeting RGD recognizing integrins: Drug development, biomaterial research, tumor imaging and targeting
A. Meyer et al.
CURRENT PHARMACEUTICAL DESIGN (2006)
Antitumor effect of RGD-4C-GG-D(KLAKLAK)(2) peptide in mouse B16(F10) melanoma model
Ryszard Smolarczyk et al.
ACTA BIOCHIMICA POLONICA (2006)
Cutting back on pro-protein convertases:: the latest approaches to pharmacological inhibition
M Fugère et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2005)
Anti-metastatic properties of RGD-peptidomimetic agents S137 and S247
KE Shannon et al.
CLINICAL & EXPERIMENTAL METASTASIS (2004)
Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients
D Anglicheau et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
Multimeric cyclic RGD peptides as potential tools for tumor targeting: Solid-phase peptide synthesis and chemoselective oxime ligation
G Thumshirn et al.
CHEMISTRY-A EUROPEAN JOURNAL (2003)
Carbohydrate-based mimetics in drug design: Sugar amino acids and carbohydrate scaffolds
SAW Gruner et al.
CHEMICAL REVIEWS (2002)
Involvement of c-Src in carcinoma cell motility and metastasis
M Sakamoto et al.
JAPANESE JOURNAL OF CANCER RESEARCH (2001)
Role of Src expression and activation in human cancer
RB Irby et al.
ONCOGENE (2000)
A peptidomimetic inhibitor of ras functionality markedly suppresses growth of human prostate tumor xenografts in mice.: Prospects for long-term clinical utility
FM Sirotnak et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2000)
New roles for Src kinases in control of cell survival and angiogenesis
J Schlessinger
CELL (2000)