4.6 Article

Exploring the potential function of trace elements in human health: a therapeutic perspective

Journal

MOLECULAR AND CELLULAR BIOCHEMISTRY
Volume 478, Issue 10, Pages 2141-2171

Publisher

SPRINGER
DOI: 10.1007/s11010-022-04638-3

Keywords

Health; Micro-nutrients; Body function; Trace elements; Diseases; Enzymes

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Trace elements are chemical elements with low concentrations, divided into essential and non-essential types. Essential trace elements are crucial for physiological and metabolic processes, and their excess or deficiency can lead to severe bodily malfunction or death. They play essential roles in biological, chemical, and molecular cell activities, and their deficits can result in weakened immunity, developmental delays, and decreased productivity. Trace element enzymes participate in various biological and chemical processes, stabilizing protein and enzyme structures and mediating crucial biological functions. Understanding trace elements is vital for maintaining optimal health and preventing disease.
A trace element, known as a minor element, is a chemical element whose concentration is very low. They are divided into essential and non-essential classes. Numerous physiological and metabolic processes in both plants and animals require essential trace elements. These essential trace elements are so directly related to the metabolic and physiologic processes of the organism that either their excess or deficiency can result in severe bodily malfunction or, in the worst situations, death. Elements can be found in nature in various forms and are essential for the body to carry out its varied functions. Trace elements are crucial for biological, chemical, and molecular cell activity. Nutritional deficits can lead to weakened immunity, increased susceptibility to oral and systemic infections, delayed physical and mental development, and lower productivity. Trace element enzymes are involved in many biological and chemical processes. These compounds act as co-factors for a number of enzymes and serve as centers for stabilizing the structures of proteins and enzymes, allowing them to mediate crucial biological processes. Some trace elements control vital biological processes by attaching to molecules on the cell membrane's receptor site or altering the structure of the membrane to prevent specific molecules from entering the cell. Some trace elements are engaged in redox reactions. Trace elements have two purposes. They are required for the regular stability of cellular structures, but when lacking, they might activate alternate routes and induce disorders. Therefore, thoroughly understanding these trace elements is essential for maintaining optimal health and preventing disease.

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