4.8 Article

Suspended Planar-Array Chips for Molecular Multiplexing at the Microscale

Journal

ADVANCED MATERIALS
Volume 28, Issue 7, Pages 1449-1454

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201504164

Keywords

chip-in-a-cell; suspended-arrays; planar-arrays; silicon chips; single-cell analysis

Funding

  1. EU ERDF (FEDER) funds
  2. Spanish Government [TEC2011-29140-C03-01/02, TEC2014-51940-C2-1/2]
  3. FSE

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CONTENTS A novel suspended planar-array chips technology is described, which effectively allows molecular multiplexing using a single suspended chip to analyze extraordinarily small volumes. The suspended chips are fabricated by combining silicon-based technology and polymer-pen lithography, obtaining increased molecular pattern flexibility, and improving miniaturization and parallel production. The chip miniaturization is so dramatic that it permits the intracellular analysis of living cells.

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