4.7 Article

Marine Sponge and Octocoral-Associated Bacteria Show Versatile Secondary Metabolite Biosynthesis Potential and Antimicrobial Activities against Human Pathogens

Related references

Note: Only part of the references are listed.
Article Biotechnology & Applied Microbiology

Heterologous expression of a cryptic gene cluster from a marine proteobacterium Thalassomonas actiniarum affords new lanthipeptides thalassomonasins A and B

Chanaphat Thetsana et al.

Summary: This study successfully produced new lanthipeptides through heterologous expression using a cryptic biosynthetic gene cluster (BGC) of the marine proteobacterium Thalassomonas actiniarum. This is the first report of heterologous production of lanthipeptides derived from proteobacterial origin, which may lead to the production of new lanthipeptides by utilizing similar BGCs.

JOURNAL OF APPLIED MICROBIOLOGY (2022)

Article Microbiology

Assessing the genomic composition, putative ecological relevance and biotechnological potential of plasmids from sponge bacterial symbionts

Vanessa Oliveira et al.

Summary: This study investigates the genomic and functional characteristics of plasmids from bacterial symbionts of marine sponges and highlights their ecological relevance in the sponge microbiome. The results suggest that plasmids play a significant role in microbial symbiont adaptation, host-microbe and microbe-microbe interactions, and may serve as an untapped resource of genes with biotechnological potential.

MICROBIOLOGICAL RESEARCH (2022)

Article Chemistry, Medicinal

Insights into the Antimicrobial Activities and Metabolomes of Aquimarina (Flavobacteriaceae, Bacteroidetes) Species from the Rare Marine Biosphere

Sandra Godinho Silva et al.

Summary: Two novel natural products, cuniculene and aquimarin, were discovered in the marine bacterial genus Aquimarina. Aquimarina strains showed inhibitory activity against Candida glabrata, marine Vibrio, and Alphaproteobacteria species. Metabolomic and genomic profiling revealed the presence of novel polyketides and peptides. Aquimarina strains were found to have low-abundance distributions worldwide across marine biotopes. This study highlights Aquimarina as a promising source of novel natural products.

MARINE DRUGS (2022)

Review Microbiology

Methods and Strategies to Uncover Coral-Associated Microbial Dark Matter

Junia Schultz et al.

Summary: This study presents the strategies and technologies used to explore cultured coral-associated microbes (CAMs) and discusses the advantages and disadvantages of each strategy. The study highlights the importance of understanding the roles of CAMs in coral health and their potential use in biotechnology.

MSYSTEMS (2022)

Article Microbiology

Metagenomics-resolved genomics provides novel insights into chitin turnover, metabolic specialization, and niche partitioning in the octocoral microbiome

Tina Keller-Costa et al.

Summary: This study is the first to recover metagenome-assembled genomes (MAGs) from dominant symbionts of octocorals, including previously unculturable Endozoicomonadaceae, Ca. Thioglobaceae, and Metamycoplasmataceae symbionts. The study identified a global role for Endozoicomonadaceae symbionts in octocorals in processing chitin, the most abundant natural polysaccharide in the oceans. Niche partitioning, metabolic specialization, and adaptation to low oxygen conditions among prokaryotic symbionts contribute to the plasticity and adaptability of the octocoral holobiont in changing marine environments.

MICROBIOME (2022)

Article Microbiology

Draft Genome Sequence of Vibrio chagasii 18LP, Isolated from Gilthead Seabream (Sparus aurata) Larvae Reared in Aquaculture

Gracinda M. M. Sanches-Fernandes et al.

Summary: The draft genome sequence of Vibrio chagasii strain 18LP, isolated from gilthead seabream larvae in Portugal, reveals various features related to opportunistic behavior, such as genes for toxin biosynthesis and tolerance, host cell invasion, and heavy metal resistance.

MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2021)

Article Biochemistry & Molecular Biology

Characterization of putative circular plasmids in sponge-associated bacterial communities using a selective multiply-primed rolling circle amplification

Vanessa Oliveira et al.

Summary: The study developed a selective smRCA-HTS method to enrich and characterize circular plasmid DNA from sponge microbial symbionts, identifying plasmids associated with the bacterial symbiont Vibrio sp. CyArs1 in the sponge host, as well as a large number of small and cryptic plasmids. Functional analysis revealed proteins involved in plasmid partitioning, maintenance, and replication, with many plasmids containing unknown genes that could potentially provide new genetic information and replication systems. The developed approach successfully enriched and characterized plasmids from bacterial isolates and sponge host microbial communities, including plasmids larger than 20 kbp.

MOLECULAR ECOLOGY RESOURCES (2021)

Article Biotechnology & Applied Microbiology

A Pseudoalteromonas Clade with Remarkable Biosynthetic Potential

Rocky Chau et al.

Summary: This study highlights the biosynthetic potential of Pseudoalteromonas strain HM-SA03, capable of producing alterochromides and potentially six other specialized metabolites. Through genomic analysis, a novel siderophore biosynthesis gene cluster with unprecedented architecture was identified in the HM-SA03 genome. Phylogenetic analysis revealed a subset of strains with extraordinary biosynthetic potential within the genus Pseudoalteromonas.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2021)

Article Biochemistry & Molecular Biology

Chemical mining of heterotrophic Shewanella algae reveals anti-infective potential of macrocyclic polyketides against multidrug-resistant pathogens

Kajal Chakraborty et al.

Summary: The study of macrocyclic polyketides isolated from Shewanella algae MTCC 12715 revealed their promising antagonistic properties against multidrug-resistant pathogens.

BIOORGANIC CHEMISTRY (2021)

Article Biotechnology & Applied Microbiology

The sponges Hymeniacidon perlevis and Halichondria panicea are reservoirs of antibiotic-producing bacteria against multi-drug resistant Staphylococcus aureus

A. Rodriguez Jimenez et al.

Summary: Cultivable bacteria associated with the marine sponges Hymeniacidon perlevis and Halichondria panicea exhibit promising antibacterial activity against multi-drug-resistant Staphylococcus aureus, indicating their potential as a valuable source of antibacterial compounds with pharmaceutical interest. This study is the first to show the antibacterial potential of these bacteria against MDR bacteria, including vancomycin nonsusceptible and methicillin-resistant strains, highlighting the urgent need for new antibiotics.

JOURNAL OF APPLIED MICROBIOLOGY (2021)

Review Biotechnology & Applied Microbiology

Prevalence and multidrug resistance in Salmonella enterica Typhimurium: an overview in South East Asia

Saumya Darshana Patra et al.

Summary: This review discusses the epidemiology and multidrug resistance of Salmonella Typhimurium in 11 countries of South East Asia. Vietnam ranks top in terms of prevalence and antimicrobial resistance, while some countries such as Brunei and Timor Leste have not conducted studies on the incidence and drug resistance of this pathogen. Despite not being the dominant serovar in the region in the past 20 years, evidence suggests that Salmonella Typhimurium remains a major threat in South East Asia due to infection in humans and contamination in animals and food sources, as well as its resistance to multiple antibiotics.

WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2021)

Article Microbiology

Functional metagenomics reveals differential chitin degradation and utilization features across free-living and host-associated marine microbiomes

I. Raimundo et al.

Summary: This study integrated cultivation-dependent and -independent approaches to uncover the chitin processing potential within marine microbiomes. The results showed differential chitin degradation pathways and utilization across marine micro-niches, as well as potential novel chitinolytic enzymes in the genus Aquimarina with applications in blue biotechnology.

MICROBIOME (2021)

Review Microbiology

Bacteria Cultivated From Sponges and Bacteria Not Yet Cultivated From Sponges-A Review

Ton That Huu Dat et al.

Summary: This review discusses the high diversity and cultivation challenges of bacteria associated with marine sponges, highlighting the need for more efficient cultivation methods and outlining promising strategies for future cultivation. Despite intensive cultivation attempts, there is a pressing need for more effective methods to isolate sponge-associated bacteria.

FRONTIERS IN MICROBIOLOGY (2021)

Article Biochemistry & Molecular Biology

Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation

Ivica Letunic et al.

Summary: The Interactive Tree Of Life is an online tool for displaying, manipulating, and annotating phylogenetic and other trees. The latest version 5 introduces a new tree display engine and several new features, such as a new dataset type and expanded annotation options. Users can now also manually annotate trees by hand, providing more flexibility and control.

NUCLEIC ACIDS RESEARCH (2021)

Article Biochemistry & Molecular Biology

antiSMASH 6.0: improving cluster detection and comparison capabilities

Kai Blin et al.

Summary: antiSMASH, a tool for detecting biosynthetic gene clusters in microorganisms, has been updated to version 6, which increases the supported cluster types, displays the structure of multi-modular BGCs, adds a new comparison algorithm, allows integration of results from other prediction tools, and improves detection of tailoring enzymes in RiPP clusters.

NUCLEIC ACIDS RESEARCH (2021)

Article Microbiology

Draft Genome Sequence of Vibrio jasicida 20LP, an Opportunistic Bacterium Isolated from Fish Larvae

Gracinda M. M. Sanches-Fernandes et al.

Summary: The genome sequence of V. jasicida 20LP from gilthead seabream larvae reveals multiple genomic features that could potentially support opportunistic associations with diverse marine animals.

MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2021)

Article Microbiology

Metagenomic insights into the taxonomy, function, and dysbiosis of prokaryotic communities in octocorals

T. Keller-Costa et al.

Summary: The study revealed distinct features of the microbiomes in octocorals using comparative metagenomics, including differences between healthy and necrotic tissues, as well as structural changes during the transition to a pathobiome state. The prokaryotic communities of healthy octocoral tissues were specific to host genus, with unique features such as the presence of uncultivated Endozoicomonadaceae and differences from the surrounding environment microbiomes.

MICROBIOME (2021)

Review Food Science & Technology

Acute Hepatopancreatic Necrosis Disease (AHPND): Virulence, Pathogenesis and Mitigation Strategies in Shrimp Aquaculture

Vikash Kumar et al.

Summary: Shrimp, a high-protein animal food commodity, is a fast-growing food producing sector globally. Disease outbreaks, particularly acute hepatopancreatic necrosis disease (AHPND) caused by Vibrio spp., have led to significant production losses and socio-economic and environmental challenges in the shrimp aquaculture industry. Current conventional approaches to mitigate AHPND, such as antibiotics and disinfectants, have shown limited success and have been linked to antibiotic resistance in bacterial pathogens.

TOXINS (2021)

Article Microbiology

Insights into the Cultured Bacterial Fraction of Corals

Michael Sweet et al.

Summary: Our study provides a comprehensive overview of the diversity and function of culturable bacteria isolated from corals across various habitats. Comparative genomic analysis uncovered potential signatures of beneficial bacterium-coral symbioses, with over 400 biosynthetic gene clusters identified. Novel genomic features potentially involved in host interactions were also discovered, suggesting new targets for coral probiotics.

MSYSTEMS (2021)

Article Microbiology

The Roseibium album (Labrenzia alba) Genome Possesses Multiple Symbiosis Factors Possibly Underpinning Host-Microbe Relationships in the Marine Benthos

Joana Fernandes Couceiro et al.

Summary: This study reveals the genomes of eight Roseibium album strains obtained from the octocoral Eunicella labiata, and identifies multiple symbiosis factors that are common to all genomes, such as eukaryotic-like repeat protein and multidrug resistance-encoding genes, which likely play a role in symbiotic relationships with marine invertebrate hosts.

MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2021)

Article Biochemistry & Molecular Biology

The IMG/M data management and analysis system v.6.0: new tools and advanced capabilities

I-Min A. Chen et al.

Summary: The Integrated Microbial Genomes & Microbiomes system at the DOE's Joint Genome Institute contains annotated genome datasets and metagenome bins, with advanced search functions and a new statistical analysis tool available in IMG v 6.0. The updated web user interface includes a Help page and webinar tutorials to assist users in understanding and utilizing various IMG functions and tools in their research. New datasets have been processed with an extended prokaryotic annotation pipeline v.5, featuring expanded protein family assignments.

NUCLEIC ACIDS RESEARCH (2021)

Review Biochemistry & Molecular Biology

The manifold roles of microbial ribosomal peptide?based natural products in physiology and ecology

Yanyan Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Article Biochemistry & Molecular Biology

A computational framework to explore large-scale biosynthetic diversity

Jorge C. Navarro-Munoz et al.

NATURE CHEMICAL BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Deletion of CDR1 reveals redox regulation of pleiotropic drug resistance in Candida glabrata

Kseniia Galkina et al.

BIOCHIMIE (2020)

Review Microbiology

List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ

Aidan C. Parte et al.

INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY (2020)

Article Biodiversity Conservation

Microbial insights from Antarctic and Mediterranean shallow-water bone-eating worms

Olivia H. Hewitt et al.

POLAR BIOLOGY (2020)

Review Microbiology

Probiotic Shewanella putrefaciens (SpPdp11) as a Fish Health Modulator: A Review

Maria Camara-Ruiz et al.

MICROORGANISMS (2020)

Review Microbiology

The Shewanella genus: ubiquitous organisms sustaining and preserving aquatic ecosystems

Olivier N. Lemaire et al.

FEMS MICROBIOLOGY REVIEWS (2020)

Review Multidisciplinary Sciences

New pathogens, new tricks: emerging, drug-resistant fungal pathogens and future prospects for antifungal therapeutics

Jennifer Geddes-McAlister et al.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2019)

Review Biochemistry & Molecular Biology

Biosynthesis and chemical diversity of β-lactone natural products

Serina L. Robinson et al.

NATURAL PRODUCT REPORTS (2019)

Article Infectious Diseases

Multidrug-Resistant Bacteria and Alternative Methods to Control Them: An Overview

Roberto Vivas et al.

MICROBIAL DRUG RESISTANCE (2019)

Review Infectious Diseases

Resistance of Candida to azoles and echinocandins worldwide

K. E. Pristov et al.

CLINICAL MICROBIOLOGY AND INFECTION (2019)

Article Biotechnology & Applied Microbiology

Labrenzbactin from a coral-associated bacterium Labrenzia sp.

Amit Raj Sharma et al.

JOURNAL OF ANTIBIOTICS (2019)

Article Biochemistry & Molecular Biology

Automated structure prediction of trans-acyltransferase polyketide synthase products

Eric J. N. Helfrich et al.

NATURE CHEMICAL BIOLOGY (2019)

Review Biotechnology & Applied Microbiology

The global burden and epidemiology of invasive non-typhoidal Salmonella infections

Ruchita Balasubramanian et al.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2019)

Review Genetics & Heredity

Candida auris and multidrug resistance: Defining the new normal

Shawn R. Lockhart

FUNGAL GENETICS AND BIOLOGY (2019)

Article Microbiology

Phylogeny and bioactivity of epiphytic Gram-positive bacteria isolated from three co-occurring antarctic macroalgae

Pamela Alvarado et al.

ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY (2018)

Article Biochemistry & Molecular Biology

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

Sudhir Kumar et al.

MOLECULAR BIOLOGY AND EVOLUTION (2018)

Letter Biotechnology & Applied Microbiology

KBase: The United States Department of Energy Systems Biology Knowledgebase

Adam P. Arkin et al.

NATURE BIOTECHNOLOGY (2018)

Review Microbiology

Host-microbe interactions in octocoral holobionts - recent advances and perspectives

Jeroen A. J. M. van de Water et al.

MICROBIOME (2018)

Review Chemistry, Medicinal

Extending the One Strain Many Compounds (OSMAC) Principle to Marine Microorganisms

Stefano Romano et al.

MARINE DRUGS (2018)

Article Microbiology

Molecular Taxonomic Profiling of Bacterial Communities in a Gilthead Seabream (Sparus aurata) Hatchery

Gianmaria Califano et al.

FRONTIERS IN MICROBIOLOGY (2017)

Review Microbiology

Beneficial Microorganisms for Corals (BMC): Proposed Mechanisms for Coral Health and Resilience

Raquel S. Peixoto et al.

FRONTIERS IN MICROBIOLOGY (2017)

Article Microbiology

The gorgonian coral Eunicella labiata hosts a distinct prokaryotic consortium amenable to cultivation

Tina Keller-Costa et al.

FEMS MICROBIOLOGY ECOLOGY (2017)

Article Biochemistry & Molecular Biology

Sponge-Associated Bacteria Produce Non-cytotoxic Melanin Which Protects Animal Cells from Photo-Toxicity

Vijitha Vijayan et al.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2017)

Review Biochemistry & Molecular Biology

Marine Sponges as a Drug Treasure

Komal Anjum et al.

BIOMOLECULES & THERAPEUTICS (2016)

Article Microbiology

Antimicrobial profile of Arthrobacter kerguelensis VL-RK_09 isolated from Mango orchards

Rajesh Kumar Munaganti et al.

BRAZILIAN JOURNAL OF MICROBIOLOGY (2016)

Article Pharmacology & Pharmacy

Methods for in vitro evaluating antimicrobial activity: A review

Mounyr Balouiri et al.

JOURNAL OF PHARMACEUTICAL ANALYSIS (2016)

Article Microbiology

Broad spectrum antimicrobial compounds from the bacterium Exiguobacterium mexicanum MSSRFS9

S. P. Shanthakumar et al.

MICROBIOLOGICAL RESEARCH (2015)

Article Biotechnology & Applied Microbiology

Application of Diffusion Growth Chambers for the Cultivation of Marine Sponge-Associated Bacteria

Georg Steinert et al.

MARINE BIOTECHNOLOGY (2014)

Article Biochemistry & Molecular Biology

Ribosomal Database Project: data and tools for high throughput rRNA analysis

James R. Cole et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Medicine, Research & Experimental

The Candida Pathogenic Species Complex

Siobhan A. Turner et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2014)

Review Oncology

Eribulin drug review

Nishitha Shetty et al.

SOUTH ASIAN JOURNAL OF CANCER (2014)

Article Microbiology

Deep-sea bacteria enriched by oil and dispersant from the Deepwater Horizon spill

Jacob Baelum et al.

ENVIRONMENTAL MICROBIOLOGY (2012)

Article Biochemical Research Methods

SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing

Anton Bankevich et al.

JOURNAL OF COMPUTATIONAL BIOLOGY (2012)

Article Biochemistry & Molecular Biology

GenBank

Dennis A. Benson et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Multidisciplinary Sciences

FastTree 2-Approximately Maximum-Likelihood Trees for Large Alignments

Morgan N. Price et al.

PLOS ONE (2010)

Review Biochemistry & Molecular Biology

Development of Yondelis (R) (trabectedin, ET-743). A semisynthetic process solves the supply problem

Carmen Cuevas et al.

NATURAL PRODUCT REPORTS (2009)

Article Biotechnology & Applied Microbiology

Stappia alba sp nov., isolated from Mediterranean oysters

MJ Pujalte et al.

SYSTEMATIC AND APPLIED MICROBIOLOGY (2005)

Article Biochemistry & Molecular Biology

Characterization of the mupirocin biosynthesis gene cluster from Pseudomonas fluorescens NCIMB 10586

AK El-Sayed et al.

CHEMISTRY & BIOLOGY (2003)

Article Agriculture, Dairy & Animal Science

Alternatives to antibiotics: Bacteriocins, antimicrobial peptides and bacteriophages

RD Joerger

POULTRY SCIENCE (2003)