Related references
Note: Only part of the references are listed.Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell-like blasts in KMT2A-rearranged leukemia
Changya Chen et al.
BLOOD (2022)
Identification and characterization of relapse-initiating cells in MLL-rearranged infant ALL by single-cell transcriptomics
Tito Candelli et al.
LEUKEMIA (2022)
Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia
Eleonora Khabirova et al.
NATURE MEDICINE (2022)
Clinical Implications of Minimal Residual Disease Detection in Infants With KMT2A-Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol
Janine Stutterheim et al.
JOURNAL OF CLINICAL ONCOLOGY (2021)
Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production
Jong Bok Lee et al.
BLOOD (2021)
Preclinical Evaluation of Carfilzomib for Infant KMT2A-Rearranged Acute Lymphoblastic Leukemia
Laurence C. Cheung et al.
FRONTIERS IN ONCOLOGY (2021)
Thermal proteome profiling identifies PIP4K2A and ZADH2 as off-targets of Polo-like kinase 1 inhibitor volasertib
Oksana Goroshchuk et al.
FASEB JOURNAL (2021)
Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLL- rearranged B cell acute lymphoblastic leukemia
Juan Ramon Tejedor et al.
JOURNAL OF CLINICAL INVESTIGATION (2021)
Venetoclax-containing regimens in acute myeloid leukemia
Ibrahim Aldoss et al.
THERAPEUTIC ADVANCES IN HEMATOLOGY (2021)
Thermal proteome profiling for interrogating protein interactions
Andre Mateus et al.
MOLECULAR SYSTEMS BIOLOGY (2020)
SynergyFinder 2.0: visual analytics of multi-drug combination synergies
Aleksandr Ianevski et al.
NUCLEIC ACIDS RESEARCH (2020)
Preclinical efficacy of gemcitabine in MLL-rearranged infant acute lymphoblastic leukemia
Priscilla Wander et al.
LEUKEMIA (2020)
Single-center pediatric experience with venetoclax and azacitidine as treatment for myelodysplastic syndrome and acute myeloid leukemia
Amanda C. Winters et al.
PEDIATRIC BLOOD & CANCER (2020)
Romidepsin enhances the efficacy of cytarabine in vivo, revealing histone deacetylase inhibition as a promising therapeutic strategy for KMT2A-rearranged infant acute lymphoblastic leukemia
Laurence C. Cheung et al.
HAEMATOLOGICA (2019)
Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study
Rob Pieters et al.
JOURNAL OF CLINICAL ONCOLOGY (2019)
Reading, writing and erasing mRNA methylation
Sara Zaccara et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Nonparametric Analysis of Thermal Proteome Profiles Reveals Novel Drug-binding Proteins
Dorothee Childs et al.
MOLECULAR & CELLULAR PROTEOMICS (2019)
Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome
Kevin K. Leung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Reading, writing and erasing mRNA methylation
Sara Zaccara et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Decitabine demonstrates antileukemic activity in B cell precursor acute lymphoblastic leukemia with MLL rearrangements
C. Roolf et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia
Daniel A. Pollyea et al.
NATURE MEDICINE (2018)
Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin
M. N. Cruickshank et al.
LEUKEMIA (2017)
DNA methylation profiling of pediatric B-cell lymphoblastic leukemia with KMT2A rearrangement identifies hypomethylation at enhancer sites
Anke K. Bergmann et al.
PEDIATRIC BLOOD & CANCER (2017)
DNA Hypomethylating Drugs in Cancer Therapy
Takahiro Sato et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Venetoclax responses of pediatric ALL xenografts reveal sensitivity of MLL-rearranged leukemia
Seong Lin Khaw et al.
BLOOD (2016)
CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
Helena Almqvist et al.
NATURE COMMUNICATIONS (2016)
Effective Targeting of the P53-MDM2 Axis in Preclinical Models of Infant MLL-Rearranged Acute Lymphoblastic Leukemia
Jennifer Richmond et al.
CLINICAL CANCER RESEARCH (2015)
Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry
Holger Franken et al.
NATURE PROTOCOLS (2015)
Acute Lymphoblastic Leukemia in Children
Stephen P. Hunger et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199
Juliana M. Benito et al.
CELL REPORTS (2015)
Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 against Pediatric Acute Lymphoblastic Leukemia Xenografts
Santi Suryani et al.
CLINICAL CANCER RESEARCH (2014)
Transcriptome-wide target profiling of RNA cytosine methyltransferases using the mechanism-based enrichment procedure Aza-IP
Vahid Khoddami et al.
NATURE PROTOCOLS (2014)
Tracking cancer drugs in living cells by thermal profiling of the proteome
Mikhail M. Savitski et al.
SCIENCE (2014)
The evolution of clinical trials for infant acute lymphoblastic leukemia
R. S. Kotecha et al.
BLOOD CANCER JOURNAL (2014)
Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia
Karen A. Urtishak et al.
BLOOD (2013)
Absence of global hypomethylation in promoter hypermethylated Mixed Lineage Leukaemia-rearranged infant acute lymphoblastic leukaemia
Dominique J. P. M. Stumpel et al.
EUROPEAN JOURNAL OF CANCER (2013)
Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
Daniel Martinez Molina et al.
SCIENCE (2013)
Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale
D. J. P. M. Stumpel et al.
LEUKEMIA (2011)
Cytotoxicity, Drug Combinability, and Biological Correlates of ABT-737 Against Acute Lymphoblastic Leukemia Cells With MLL Rearrangement
Aarthi Jayanthan et al.
PEDIATRIC BLOOD & CANCER (2011)
Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting
Eric Schafer et al.
BLOOD (2010)
Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options
Dominique J. P. M. Stumpel et al.
BLOOD (2009)
Abundant anti-apoptotic BCL-2 is a molecular target in leukaemias with t(4;11) translocation
Blaine W. Robinson et al.
BRITISH JOURNAL OF HAEMATOLOGY (2008)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells
J Worm et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)