4.8 Article

Rezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE) : a multicentre, double-blind, double-dummy, randomised phase 3 trial

Related references

Note: Only part of the references are listed.
Article Immunology

Rezafungin Versus Caspofungin in a Phase 2, Randomized, Double-blind Study for the Treatment of Candidemia and Invasive Candidiasis: The STRIVE Trial

George R. Thompson et al.

Summary: The study findings demonstrate that Rezafungin is effective and safe for the treatment of candidemia and/or invasive candidiasis, with high cure rates and clinical responses.

CLINICAL INFECTIOUS DISEASES (2021)

Article Immunology

Invasive Candidiasis Species Distribution and Trends, United States, 2009-2017

Emily E. Ricotta et al.

Summary: The study found that the incidence of invasive candidiasis (IC) in the United States is relatively stable, primarily caused by Candida albicans, while nonbloodstream IC is on the rise.

JOURNAL OF INFECTIOUS DISEASES (2021)

Article Microbiology

Rezafungin: a novel antifungal for the treatment of invasive candidiasis

Young Yoon Ham et al.

Summary: Rezafungin is a promising novel echinocandin with exceptional stability, solubility, and a uniquely long half-life, allowing for infrequent dosing. Clinical data demonstrate its comparable efficacy to other echinocandins, with broad-spectrum activity against fungal pathogens. Ongoing trials are evaluating its effectiveness in treating and preventing fungal infections, showing robust safety and promising efficacy in clinical settings.

FUTURE MICROBIOLOGY (2021)

Article Immunology

982. Effect of Hepatic Impairment on the Safety and Pharmacokinetics of Rezafungin

Jade Huguet et al.

Open Forum Infectious Diseases (2021)

Article Microbiology

Population Pharmacokinetics of Rezafungin in Patients with Fungal Infections

Christopher M. Rubino et al.

Summary: A population pharmacokinetic model was developed to characterize the disposition of rezafungin in plasma following IV administration, showing significant relationships between subject descriptors and rezafungin PK parameters. The final model provided a precise and unbiased fit to observed concentrations and can reliably predict rezafungin PK in infected patients.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2021)

Article Immunology

Estimation of Direct Healthcare Costs of Fungal Diseases in the United States

Kaitlin Benedict et al.

CLINICAL INFECTIOUS DISEASES (2019)

Article Infectious Diseases

We can do better: a fresh look at echinocandin dosing

Justin C. Bader et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2018)

Article Medicine, General & Internal

Invasive candidiasis

Peter C. Pappas et al.

NATURE REVIEWS DISEASE PRIMERS (2018)

Article Microbiology

Safety and Pharmacokinetics of CD101 IV, a Novel Echinocandin, in Healthy Adults

Taylor Sandison et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)

Article Microbiology

Pharmacological Basis of CD101 Efficacy: Exposure Shape Matters

Elizabeth A. Lakota et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)

Article Cell Biology

CD101: a novel long-acting echinocandin

Yanan Zhao et al.

CELLULAR MICROBIOLOGY (2016)

Article Microbiology

Abdominal Candidiasis Is a Hidden Reservoir of Echinocandin Resistance

Ryan K. Shields et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)

Review Microbiology

Tissue Penetration of Antifungal Agents

Timothy Felton et al.

CLINICAL MICROBIOLOGY REVIEWS (2014)

Article Immunology

Septic Shock Attributed to Candida Infection: Importance of Empiric Therapy and Source Control

Marin Kollef et al.

CLINICAL INFECTIOUS DISEASES (2012)

Review Infectious Diseases

ESCMID* guideline for the diagnosis and management of Candida diseases 2012: non-neutropenic adult patients

O. A. Cornely et al.

CLINICAL MICROBIOLOGY AND INFECTION (2012)

Article Immunology

Micafungin versus caspofungin for treatment of candidemia and other forms of invasive candidiasis

Peter G. Pappas et al.

CLINICAL INFECTIOUS DISEASES (2007)

Article Medicine, General & Internal

Anidulafungin versus fluconazole for invasive candidiasis

Annette C. Reboli et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Article Infectious Diseases

International, open-label, noncomparative, clinical trial of micafungin alone and in combination for treatment of newly diagnosed and refractory candidemia

L Ostrosky-Zeichner et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2005)

Article Medicine, General & Internal

Comparison of caspofungin and amphotericin B for invasive candidiasis.

J Mora-Duarte et al.

NEW ENGLAND JOURNAL OF MEDICINE (2002)