Endemic rise in cases of acute kidney injury in children in Indonesia and Gambia: what is the likely culprit and why?

A sudden rise in the cases of acute kidney injury (AKI) has been reported in Indonesia and Gambia that has been linked to the consumption of tainted syrup medications for cough, colds, pain, and fever. Preliminary investigations revealed multiple lapses in quality control during manufacturing including substitution of diethylene glycol (DEG) and ethylene glycol (EG) for the more expensive but non-toxic solvent glycerol. In this editorial report, we shed light upon the current situation and urge the investigating authorities to make those responsible accountable to regain public trust.

Automated summary

A sudden increase in cases of acute kidney injury (AKI) in Indonesia and Gambia has been linked to the consumption of syrup medications contaminated with diethylene glycol (DEG) and ethylene glycol (EG). Preliminary investigations found lapses in quality control during manufacturing, including the substitution of the toxic solvents with the non-toxic solvent glycerol. This editorial report highlights the current situation and calls for accountability from the investigating authorities to restore public trust.